Chitosan oligosaccharide

By Targets:	AMPK (1) Biochemical Assay Reagents (1) Endogenous Metabolite (2) Reactive Oxygen Species (ROS) (1) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Inflammation/Immunology (5) Metabolic Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112108

**Chitosan oligosaccharide** 4 Publications Verification COS	AMPK Endogenous Metabolite	Metabolic Disease Cancer
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activates AMPK and inhibits inflammatory signaling pathways including NF-κB and MAPK pathways.

HY-P2859

Chitosanase	Endogenous Metabolite	Metabolic Disease
Chitosanase is a glycosyl hydrolase that catalyzes the endo hydrolysis of β-1,4-glycosidic bonds of partially acetylated chitosan to release chitosan oligosaccharides (COS). Chitosanases can convert high molecular weight chitosan into functional chitooligosaccharides with low molecular weight .

HY-N7697B

Chitobiose dihydrochloride	Others	Others
Chitobiose dihydrochloride, a chitosan oligosaccharide, is a dimer of β-1,4-linked glucosamine units .

HY-N7697A

Chitopentaose pentahydrochloride	Others	Inflammation/Immunology
Chitopentaose pentahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitopentaose pentahydrochloride is a substrate of gene encoding chitinase B (FjchiB) .

HY-N7697C

Chitohexaose hexahydrochloride	Toll-like Receptor (TLR)	Inflammation/Immunology
Chitohexaose hexahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitohexaose hexahydrochloride binds to the active sites of TLR4 and inhibits LPS induced inflammation .

HY-N7697D

Chitoheptaose heptahydrochloride	Reactive Oxygen Species (ROS)	Cardiovascular Disease Inflammation/Immunology
Chitoheptaose heptahydrochloride is a chitosan oligosaccharide with antioxidant, anti-inflammatory, antiapoptotic and cardioprotective activities. Chitoheptaose heptahydrochloride significantly enhances the growth and photosynthesis parameters of wheat seedlings .

HY-N7697F

Chitobiose	Others	Others
Chitobiose, a chitosan oligosaccharide, is a dimer of β-1,4-linked glucosamine units . Chitobiose has orally activity and high antioxidant activity .

HY-W145695

Chitoheptaose	Biochemical Assay Reagents	Inflammation/Immunology
Chitoheptaose is a chitosan oligosaccharide. Chitoheptaose is capable of extracting exoskeletons from crustaceans, such as the shells of crabs, shrimp and lobsters. Chitoheptaose has antioxidant, anti-inflammatory and anti-apoptotic activities and can be used in the study of myocarditis. Chitoheptaose has cardioprotective effects and improves cardiac parameters (left ventricular internal size, end-systolic and end-diastolic, ejection fraction and shortening fraction), inflammatory cytokines (IL-1β) in vanishing models .

HY-D1056B1

Lipopolysaccharides, from Proteus vulgaris LPS, from bacterial (Proteus vulgaris)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides, from Proteus vulgaris are lipopolysaccharide endotoxins and TLR-4 activators derived from Proteus vulgaris, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from Proteus vulgaris exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from Proteus vulgaris possess a unique molecular structure and chitosan affinity (K_b=2.72 μM), surpassing that of Yersinia pseudotuberculosis (K_b=6.06 μM) and Escherichia coli (K_b=79.50 μM) . It is recommended to prepare a stock solution of ≥2 mg/mL and ensure that it is fully mixed and dissolved. Due to the adsorption characteristics of LPS, low adsorption centrifuge tubes should be used for aliquoting and storage.

Cat. No.	Product Name	Type

HY-W145695

Chitoheptaose	Biochemical Assay Reagents
Chitoheptaose is a chitosan oligosaccharide. Chitoheptaose is capable of extracting exoskeletons from crustaceans, such as the shells of crabs, shrimp and lobsters. Chitoheptaose has antioxidant, anti-inflammatory and anti-apoptotic activities and can be used in the study of myocarditis. Chitoheptaose has cardioprotective effects and improves cardiac parameters (left ventricular internal size, end-systolic and end-diastolic, ejection fraction and shortening fraction), inflammatory cytokines (IL-1β) in vanishing models .

Chitoheptaose

Biochemical Assay Reagents

Chitoheptaose is a chitosan oligosaccharide. Chitoheptaose is capable of extracting exoskeletons from crustaceans, such as the shells of crabs, shrimp and lobsters. Chitoheptaose has antioxidant, anti-inflammatory and anti-apoptotic activities and can be used in the study of myocarditis. Chitoheptaose has cardioprotective effects and improves cardiac parameters (left ventricular internal size, end-systolic and end-diastolic, ejection fraction and shortening fraction), inflammatory cytokines (IL-1β) in vanishing models .

HY-D1056B1

Lipopolysaccharides, from Proteus vulgaris LPS, from bacterial (Proteus vulgaris)	Carbohydrates
Lipopolysaccharides, from Proteus vulgaris are lipopolysaccharide endotoxins and TLR-4 activators derived from Proteus vulgaris, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from Proteus vulgaris exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from Proteus vulgaris possess a unique molecular structure and chitosan affinity (K_b=2.72 μM), surpassing that of Yersinia pseudotuberculosis (K_b=6.06 μM) and Escherichia coli (K_b=79.50 μM) . It is recommended to prepare a stock solution of ≥2 mg/mL and ensure that it is fully mixed and dissolved. Due to the adsorption characteristics of LPS, low adsorption centrifuge tubes should be used for aliquoting and storage.

Lipopolysaccharides, from Proteus vulgaris

LPS, from bacterial (Proteus vulgaris)

Carbohydrates

Lipopolysaccharides, from Proteus vulgaris are lipopolysaccharide endotoxins and TLR-4 activators derived from Proteus vulgaris, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from Proteus vulgaris exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from Proteus vulgaris possess a unique molecular structure and chitosan affinity (K_b=2.72 μM), surpassing that of Yersinia pseudotuberculosis (K_b=6.06 μM) and Escherichia coli (K_b=79.50 μM) .
It is recommended to prepare a stock solution of ≥2 mg/mL and ensure that it is fully mixed and dissolved. Due to the adsorption characteristics of LPS, low adsorption centrifuge tubes should be used for aliquoting and storage.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-112108

**Chitosan oligosaccharide** 4 Publications Verification COS	Structural Classification Polysaccharides Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Cancer	AMPK Endogenous Metabolite
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activates AMPK and inhibits inflammatory signaling pathways including NF-κB and MAPK pathways.

HY-N7697B

Chitobiose dihydrochloride	Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields Saccharides	Others
Chitobiose dihydrochloride, a chitosan oligosaccharide, is a dimer of β-1,4-linked glucosamine units .

HY-N7697A

Chitopentaose pentahydrochloride	Microorganisms Classification of Application Fields Source classification Disease Research Fields Inflammation/Immunology Saccharides	Others
Chitopentaose pentahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitopentaose pentahydrochloride is a substrate of gene encoding chitinase B (FjchiB) .

HY-N7697C

Chitohexaose hexahydrochloride	Classification of Application Fields Animals Source classification Disease Research Fields Inflammation/Immunology Saccharides	Toll-like Receptor (TLR)
Chitohexaose hexahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitohexaose hexahydrochloride binds to the active sites of TLR4 and inhibits LPS induced inflammation .

HY-N7697D

Chitoheptaose heptahydrochloride	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Reactive Oxygen Species (ROS)
Chitoheptaose heptahydrochloride is a chitosan oligosaccharide with antioxidant, anti-inflammatory, antiapoptotic and cardioprotective activities. Chitoheptaose heptahydrochloride significantly enhances the growth and photosynthesis parameters of wheat seedlings .

HY-N7697F

Chitobiose	Polysaccharides Microorganisms Classification of Application Fields Animals Source classification Other Diseases Disease Research Fields Saccharides	Others
Chitobiose, a chitosan oligosaccharide, is a dimer of β-1,4-linked glucosamine units . Chitobiose has orally activity and high antioxidant activity .

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Chitosan oligosaccharide

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Biochemical Assay Reagents

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