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Cephalosporin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (4) Akt (2) Antibiotic (198) Apoptosis (1) Aurora Kinase (6) Bacterial (217) Beta-lactamase (30) Drug Intermediate (6) Drug Metabolite (10) EAAT (5) Endogenous Metabolite (2) GSK-3 (6) Interleukin Related (1) Isotope-Labeled Compounds (23) mTOR (2) NF-κB (1) Orthopoxvirus (1) p38 MAPK (1) Penicillin-binding protein (PBP) (31) PPAR (2) Prostaglandin Receptor (2) PTEN (2) Reactive Oxygen Species (ROS) (1) Reference Standards (61) TNF Receptor (1) TOPK (4)
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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1299

Cephalosporin C 1 Publications Verification	Bacterial	Infection
Cephalosporin C has weak resistance to Gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Hydrolysis and removal of side chains to obtain 7-amino-cefenoic acid (7-ACA) is an important raw material for the preparation of semi-synthetic cephalosporin .

HY-B1299A

Cephalosporin C zinc salt 1 Publications Verification	Bacterial Orthopoxvirus Antibiotic	Infection Inflammation/Immunology
Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC₅₀ of 1.1 μM . Cephalosporin C zinc salt also has moderate anti-orthopoxvirus activity .

HY-W764182

Cephalosporinase,bacillus	Antibiotic	Infection
Cephalosporinase, bacillus are enzymes produced by bacillus, inactivated and degrade the ability of the cephalosporin class of antibiotics. Cephalosporins are a class of β-lactam antibiotics that are widely used to treat bacterial infections .

HY-E70137

*AMG 118 (Immobilized cephalosporin* C acylase)**	Drug Intermediate	Others
AMG 118 Immobilized cephalosporin C acylase is an enzyme that catalyzes in immobilized form and is generally used in industrial catalytic production of the important pharmaceutical intermediate 7-aminocephalosporanic acid (7-ACA). It contains CPC acylase, a highly specialized beta-lactam acylase or peptidase that cleaves the amide bonds between beta-lactams .

HY-177567A

Cephalosporin C analog-1 sodium	Bacterial	Infection
Cephalosporin C analog-1 (sodium) is an analogue of Cephalosporin C (HY-B1299). Cephalosporin C has weak resistance to Gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Hydrolysis and removal of side chains to obtain 7-amino-cefenoic acid (7-ACA) is an important raw material for the preparation of semi-synthetic cephalosporin .

HY-177567

Cephalosporin C analog-1	Bacterial	Infection
Cephalosporin C analog-1 is an analogue of Cephalosporin C (HY-B1299). Cephalosporin C has weak resistance to Gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Hydrolysis and removal of side chains to obtain 7-amino-cefenoic acid (7-ACA) is an important raw material for the preparation of semi-synthetic cephalosporin .

HY-144229

trans-Cephalosporin	Beta-lactamase	Inflammation/Immunology
Trans substituted cephalosporin is an effective NDM-1 inhibitor，with an IC₅₀ value of 0.13 μM.

HY-123271

Ro 23-9424	Bacterial Antibiotic	Infection
Ro 23-9424 is a broad-spectrum cephalosporin composed of a cephalosporin and a quinolone moiety. Ro 23-9424 shows antimicrobial activity in vivo and in vitro .

HY-125455

Ro 41-1879	Bacterial	Infection
Ro 41-1879 is a catechol cephalosporin that has antimicrobial activity .

HY-135889

CPFX2090	Bacterial	Infection
CPFX2090 is a cephalosporin antibacterial compound extracted from patent WO2013052568A1, Compound Example 16g .

HY-108877

Cefepime hydrochloride BMY-28142 hydrochloride	Antibiotic Bacterial	Infection
Cefepime hydrochloride is a cephalosporin antibiotic agent. Cefepime hydrochloride has inhibitory activity against human serum paraoxonase-1 (hPON1) with an IC₅₀ value of 21.115 mM .

HY-B0875B

Cefmenoxime sodium SCE-1365 sodium	Antibiotic Bacterial	Infection
Cefmenoxime sodium is a new semisynthetic cephalosporin antibiotic. Cefmenoxime sodium has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .

HY-135372

Descarbamoyl cefuroxime	Drug Metabolite	Infection
Descarbamoyl cefuroxime is a degradation product of Cefuroxime. Descarbamoyl cefuroxime is also an intermediate for the synthesis of Cephalosporin antibiotics .

HY-B1682

Loracarbef	Antibiotic Bacterial	Infection
Loracarbef, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .

HY-B1682A

Loracarbef hydrate	Antibiotic Bacterial	Infection
Loracarbef hydrate, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .

HY-B0875

Cefmenoxime hydrochloride SCE-1365 hydrochloride	Antibiotic Bacterial	Infection
Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .

HY-B0875A

Cefmenoxime SCE-1365	Antibiotic Bacterial	Infection
Cefmenoxime (SCE-1365) is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .

HY-B1825

Cefoxitin 5+ Cited Publications	Antibiotic Bacterial Beta-lactamase	Infection
Cefoxitin is a cephalosporin-class antibiotic. Cefoxitin is highly stable against β-Lactamase (HY-P2998). Cefoxitin has a broad spectrum of antibacterial activity, including Gram-negative and Gram-positive bacteria .

HY-123137

Ro 24-6778	Bacterial	Infection
Ro 24-6778 is a cephalosporin composed of Desacetylcefotaxime (HY-126129) and Desmethylfleroxacin ester-linked. Ro 24-6778 has high antibacterial activity against a wide range of aerobic bacteria .

HY-B0875R

Cefmenoxime hydrochloride (Standard) SCE-1365 hydrochloride (Standard)	Reference Standards Antibiotic Bacterial	Infection
Cefmenoxime (hydrochloride) (Standard) is the analytical standard of Cefmenoxime (hydrochloride). This product is intended for research and analytical applications. Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria .

HY-B0698

Ceftibuten Sch 39720	Beta-lactamase Bacterial Antibiotic	Infection
Ceftibuten (Sch39720), an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens .

HY-B0698B

Ceftibuten monohydrate Sch 39720 monohydrate	Beta-lactamase Bacterial Antibiotic	Infection
Ceftibuten (Sch39720) monohydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens .

HY-B0698A

Ceftibuten dihydrate 2 Publications Verification Sch-39720 dihydrate	Beta-lactamase Bacterial Antibiotic	Infection
Ceftibuten (Sch-39720) dihydrate, an antibiotic, is an orally active cephalosporin, possesses potent activity in vitro against a wide range of gram-negative and certain gram-positive pathogens .

HY-105049

Ceftaroline 1 Publications Verification T-91825; PPI-0903M	Bacterial	Infection
T-91825 (PPI-0903M), an N-phosphono-type cephalosporin, is the active form of TAK-599. T-91825 is active against both gram-positive and gram-negative bacteria .

HY-105393

LB 10517 sodium Antibiotic LB 10517 sodium	Bacterial	Infection
LB 10517 (sodium) is a type of cephalosporin. LB 10517 (sodium) has broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus, and Streptococcus .

HY-B1825R

Cefoxitin (Standard)	Reference Standards Antibiotic Bacterial Beta-lactamase	Infection
Cefoxitin (Standard) is the analytical standard of Cefoxitin. This product is intended for research and analytical applications. Cefoxitin is a cephalosporin-class antibiotic. Cefoxitin is highly stable against β-Lactamase (HY-P2998). Cefoxitin has a broad spectrum of antibacterial activity, including Gram-negative and Gram-positive bacteria .

HY-106084

Cefteram T-2525; RO 19-5247; Cefterame	Bacterial	Infection
Cefteram (T-2525) is the free acid of Cefteram pivoxil (HY-106571), which is an orally active cephalosporin ester. Cefteram potently targets to the enteropathogenic Enterobacteriaceae and Vibrionaceae .

HY-A0111B

Cefetamet hydrochloride Ro 15-8074 hydrochloride; Deacetoxycefotaxime hydrochloride	Antibiotic Bacterial Penicillin-binding protein (PBP) Drug Metabolite	Infection
Cefetamet (Ro 15-8074) hydrochloride is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet hydrochloride binds to bacterial penicillin-binding protein (PBP) (IC₅₀ for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet hydrochloride has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet hydrochloride kills and lyses Treponema pallidum. Cefetamet hydrochloride can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis .

HY-B0734B

Cefotiam dihydrochloride hydrate SCE-963 dihydrochloride hydrate	Antibiotic Bacterial	Infection
Cefotiam (SCE-963) dihydrochloride hydrate is a parenteral cephalosporin antibiotic. Cefotiam dihydrochloride hydrate has broad-spectrum activity against Gram-positive and Gram-negative bacteria .

HY-B0734A

Cefotiam hydrochloride SCE-963 hydrochloride	Antibiotic Bacterial	Infection
Cefotiam (SCE-963) hydrochloride is a parenteral cephalosporin antibiotic. Cefotiam hydrochloride has broad-spectrum activity against Gram-positive and Gram-negative bacteria .

HY-B0734

Cefotiam SCE-963; Cefotiam Dihydrochloride	Antibiotic Bacterial	Infection
Cefotiam (SCE-963) is a parenteral cephalosporin antibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria .

HY-B0136

Cefdinir 3 Publications Verification FK-482; CI-983	Bacterial Antibiotic	Infection
Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-N7101

Cefpodoxime Proxetil U-76,252; CS-807	Bacterial Antibiotic Penicillin-binding protein (PBP)	Infection
Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .

HY-P3519

ACV Tripeptide	Drug Intermediate	Others
ACV Tripeptide is a key biosynthetic precursor of penicillin and cephalosporins and is found in Penicillium chrysogenum and Acremonium chrysogenum. ACV Tripeptide is synthesized by a large non-ribosomal peptide synthase called ACV synthase, which is encoded by the 11 kb The pchAB gene encodes this enzyme .

HY-113590

FR295389	Bacterial	Infection
FR295389 is a dihydroimidazopyrazolium cephalosporin with antibacterial activity. FR295389 shows activity against IMP-type metallo-β-lactamases (MBL)-producing Klebsiella pneumoniae, Acinetobacter baumanii and Pseudomonas putida with MIC values ranging from 4 to 32 mg/mL .

HY-N7101R

Cefpodoxime Proxetil (Standard) U-76,252 (Standard); CS-807 (Standard)	Reference Standards Bacterial Antibiotic Penicillin-binding protein (PBP)	Infection
Cefpodoxime Proxetil (Standard) is the analytical standard of Cefpodoxime Proxetil. This product is intended for research and analytical applications. Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .

HY-B0186A

Cefoselis hydrochloride	Bacterial Antibiotic	Infection
Cefoselis hydrochloride, the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis hydrochloride exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis hydrochloride penetrates the blood-brain barrier .

HY-B0186

Cefoselis	Bacterial Antibiotic	Infection
Cefoselis, the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis penetrates the blood-brain barrier .

HY-106574

Ceftobiprole medocaril BAL5788	Bacterial	Infection Inflammation/Immunology
Ceftobiprole medocaril (BAL5788) is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

HY-106574A

Ceftobiprole medocaril sodium BAL5788 sodium	Bacterial	Infection Inflammation/Immunology
Ceftobiprole medocaril (BAL5788) sodium is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens .

HY-B0692A

Cefepime chloride BMY-28142 chloride	Penicillin-binding protein (PBP) Antibiotic Bacterial	Infection Cancer
Cefepime (BMY-28142) chloride is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime chloride shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime chloride induces neurotoxicity .

HY-B0692

Cefepime 10+ Cited Publications BMY-28142	Penicillin-binding protein (PBP) Antibiotic Bacterial	Infection Cancer
Cefepime (BMY-28142) is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime induces neurotoxicity .

HY-B1252

Cefalonium	Antibiotic Bacterial	Infection Inflammation/Immunology
Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-B1252A

Cefalonium hydrate	Antibiotic Bacterial	Infection Inflammation/Immunology
Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-B0136R

Cefdinir (Standard) FK-482 (Standard); CI-983 (Standard)	Reference Standards Bacterial Antibiotic	Infection
Cefdinir (Standard) is the analytical standard of Cefdinir. This product is intended for research and analytical applications. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-16137

Cefaloglycin Cephaloglycin	Bacterial	Infection
Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration .

HY-B0771

Cefozopran SCE-2787	Bacterial Antibiotic	Infection
Cefozopran (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .

HY-B0771A

Cefozopran hydrochloride SCE-2787 hydrochloride	Bacterial Antibiotic	Infection
Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran hydrochloride, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .

HY-B0186B

Cefoselis sulfate FK-037	Bacterial Antibiotic	Infection
Cefoselis sulfate (FK-037), the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis sulfate exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis sulfate penetrates the blood-brain barrier .

HY-19071

BK-218	Antibiotic Bacterial	Infection
BK-218 is an orally active cephalosporin antibiotic that binds to penicillin-binding proteins (PBPs) and has a greater inhibitory effect than Cephalexin (HY-B0200) and Cefoxitin (HY-B1825). BK-218 has similar antibacterial activity to Cefamandole (HY-B1128) and can be used in the development of antibacterial drugs .

Cat. No.	Product Name

HY-L067

Antibiotics Library

745 compounds

Antibiotics are types of antimicrobial products used for the treatment and prevention of bacterial infections. Antibiotics can kill or inhibit bacterial growth. Although the target of an antibiotic is bacteria, some antibiotics also attack fungi and protozoans. However, antibiotics rarely have an effect on viruses. The major mechanism underlying antibiotics is the inhibition or regulation of enzymes involved in cell wall biosynthesis, nucleic acid metabolism and repair, protein synthesis, or disruption of membrane structure. Many of these cellular functions targeted by antibiotics are most active in multiplying cells. Since there is often overlap in these functions between prokaryotic bacterial cells and eukaryotic mammalian cells, it is not surprising that some antibiotics have also been found to be useful as anticancer agents.

MCE supplies a unique collection of 745 antibiotics, including penicillins, cephalosporins, tetracyclines, macrolides, etc. MCE Antibiotics Library is a useful tool for anti-bacterial or anti-cancer drugs discovery.

Cat. No.	Product Name	Type

HY-121694

CENTA	Dyes
CENTA is a colorimetric cephalosporin substrate for β-lactamases. Upon hydrolysis by β-lacatamases, CENTA turns from light yellow to chrome yellow, which can be quantified by colorimetric detection at 405 nm as a measure of β-lactamase activity.

Cat. No.	Product Name	Target	Research Area

HY-P3519

ACV Tripeptide	Drug Intermediate	Others
ACV Tripeptide is a key biosynthetic precursor of penicillin and cephalosporins and is found in Penicillium chrysogenum and Acremonium chrysogenum. ACV Tripeptide is synthesized by a large non-ribosomal peptide synthase called ACV synthase, which is encoded by the 11 kb The pchAB gene encodes this enzyme .

HY-P3519A

ACV Tripeptide TFA	Drug Intermediate	Others
ACV Tripeptide TFA is the TFA form of ACV Tripeptide (HY-P3519). ACV Tripeptide TFA is a key biosynthetic precursor of penicillin and cephalosporins and is found in Penicillium chrysogenum and Acremonium chrysogenum. ACV Tripeptide TFA is synthesized by a large non-ribosomal peptide synthase called ACV synthase .

HY-P2011

Cephabacin M4	Bacterial	Infection
Cephabacin M4 is a cephalosporin component, a 7-methoxydesacetylcephalosporin. Cephabacin M4 can be isolated from the culture filtrate of Xanthomonas lactamica.

HY-P2038

Cephabacin M6	Bacterial	Infection
Cephabacin M6 is a cephalosporin component, a 7-methoxydesacetylcephalosporin. Cephabacin M6 can be isolated from the culture filtrate of Xanthomonas lactamica.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121144

Cefazedone Refosporen	Infection Animals Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria .

HY-B1434

7-Aminocephalosporanic acid 2 Publications Verification 7-ACA	Infection Classification of Application Fields Disease Research Fields	Beta-lactamase Bacterial Antibiotic
7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor .

HY-D0184R

2'-Deoxycytidine (Standard) Deoxycytidine (Standard); Cytosine deoxyriboside (Standard); Deoxyribose cytidine (Standard)	Natural Products Microorganisms Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .

HY-N14528

Oganomycin A	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Oganomycin A is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .

HY-N14529

Oganomycin B	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Oganomycin B is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria .

HY-113629R

2-Keto-D-Glucose (Standard) D-Glucosone (Standard); D-Arabino-hexos-2-ulose (Standard)	Source classification Endogenous metabolite Saccharides	Drug Metabolite Reference Standards
Cefixime (trihydrate) (Standard) is the analytical standard of Cefixime (trihydrate). This product is intended for research and analytical applications. Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections .

HY-121144R

Cefazedone (Standard) Refosporen (Standard)	Animals Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Reference Standards Antibiotic Bacterial
Cefazedone (Standard) (Refosporen (Standard)) is the analytical standard of Cefazedone (HY-121144). This product is intended for research and analytical applications. Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria .

HY-N14918

N-(2,6-Diamino-6-hydroxymethylpimelyl)-L-alanine	Natural Products Microorganisms Source classification	Bacterial
N-(2,6-Diamino-6-hydroxymethylpimelyl)-L-alanine shows anti-Escherichia coli activity, and is combined with several cell wall synthesis inhibitors such as Fosfomycin, Cycloserine, Penicillin, and Cephalosporin, the combination of sporozoin has obvious synergistic antibacterial effect .

Cat. No.	Compare	Product Name	Species	Source

HY-P701944

	Cephalosporin C deacetylase Protein, Bacillus subtilis cah; Cephalosporin-C deacetylase; Acetylxylan esterase	Others	E. coli
	Cephalosporin C deacetylase Protein, an esterase, selectively removes acetyl groups from substrates like acetylated xylose and cephalosporin C. Its catalytic activity excludes polymeric acetylated xylan and amide linkages, highlighting its nuanced, targeted deacetylation function. Cephalosporin C deacetylase Protein, Bacillus subtilis is the recombinant Cephalosporin C deacetylase protein, expressed by E. coli , with tag free.

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Cat. No.	Product Name	Chemical Structure

HY-B1252AS

Cefalonium-d4 hydrate
Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-W654101

Cefotaxime-d3
Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-B0210S

Cefoperazone-d5
Cefoperazone-d₅ is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-A0088S

Cefotaxime-d3 sodium
Cefotaxime-d₃ (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-B1256S

Cefuroxime-d3
Cefuroxime-d₃ is deuterium labeled Cefuroxime (sodium). Cefuroxime sodium is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime sodium has a broad spectrum activity against Gram-positive and Gram-negative bacteria .

HY-B0712S

Ceftriaxone-d3 disodium
Ceftriaxone-d₃ (disodium) is the deuterium labeled Ceftriaxone. Ceftriaxone is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics .

HY-106257S

Ceftolozane-d6 TFA
Ceftolozane-d₆ TFA is a deuterated labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer .

HY-W654098

Cefazolin-13C2,15N sodium
Cefazolin- ¹³C₂, ¹⁵N (sodium) is ¹³C and ¹⁵N labeled Cefazolin (sodium). Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).

HY-17628S1

Cefiderocol-d6
Cefiderocol-d₆ (S-649266-d₆) is a deuterated labeled Cefiderocol (HY-17628). Cefiderocol is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less .

HY-B0458AS

Cefprozil-d4
Cefprozil-d₄ is the deuterium labeled Cefprozi (HY-B0458A) . Cefprozil is a second-generation cephalosporin type antibiotic. Cefprozil exhibits broad-spectrum antibacterial activity, and is orally active. Cefprozil can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections .

HY-B0200BS

Cephalexin-d5 monohydrate

Cephalexin-d₅ (monohydrate) is the deuterium labeled Cephalexin monohydrate. Cephalexin monohydrate is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin monohydrate kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-B0200S

Cephalexin-d5
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation?cephalosporin antibiotic. Cephalexin kills?gram-positive?and some?gram-negative bacteria?by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of?pneumonia,?strep throat, and bacterial endocarditis, et al .

HY-B1892S1

Cefazolin-13C2,15N
Cefazolin- ¹³C₂, ¹⁵N (Cephazolin- ¹³C₂, ¹⁵N) is ¹³C and ¹⁵N labeled Cefazolin. Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .

HY-W770956

Cefotiam-13C,15N2
Cefotiam- ¹³C, ¹⁵N₂ (SCE-963- ¹³C, ¹⁵N₂) is the ¹³C- and ¹⁵N-labeled Cefotiam (HY-B0734). Cefotiam (SCE-963) is a parenteral cephalosporin antibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria .

HY-N7101S1

Cefpodoxime Proxetil-d6

Cefpodoxime Proxetil-d₆ (U-76,252-d₆) is deuterium labeled Cefpodoxime Proxetil. Cefpodoxime proxetil is an orally administered broad spectrum third-generation cephalosporin. Cefpodoxime proxetil has anti-bacterial activity. Cefpodoxime proxetil binds to penicillin binding proteins (PBPs) which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis .

HY-19806S1

Ceftolozane-15N2,d4 TFA
Ceftolozane- ¹⁵N₂,d₄ (CXA-101- ¹⁵N₂,d₄) TFA is the ¹⁵N- and deuterium-labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer .

HY-W653936

Cephalexin-d5 hydrate

Cephalexin-d₅ (hydrate) is deuterium labeled Cephalexin (monohydrate). Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

HY-B0136S

Cefdinir-13C,15N2

Cefdinir- ¹³C, ¹⁵N₂ (FK-482- ¹³C, ¹⁵N₂) is ¹³C and ¹⁵N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-B1190S

Cefadroxil-d4 hydrate

Cefadroxil-d₄ (hydrate) is the deuterium labeled Cefadroxil hydrate (HY-B1190A). Cefadroxil hydrate is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil hydrate inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil hydrate is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil hydrate has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain .

HY-W740028

Cefditoren-d3 sodium

Cefditoren-d₃ (sodium) (ME 1206-d₃) is deuterium labeled Cefditoren (sodium). Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .

HY-17452AS

Cefditoren Pivoxil-d3

Cefditoren Pivoxil-d₃ (Cefditoren pivoxyl-d₃) is deuterium labeled Cefditoren Pivoxil. Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .

HY-B1190S2

Cefadroxil-13C6

Cefadroxil- ¹³C₆ (BL-S 578- ¹³C₆) is ¹³C labeled Cefadroxil (HY-B1190). Cefadroxil is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain .

HY-B0712S1

Ceftriaxone-13C2,d3 triethylammonium salt

Ceftriaxone- ¹³C₂,d₃ triethylammonium salt is ¹³C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .

HY-W743473

Cefetamet-d3

Cefetamet-d₃ (Ro 15-8074-d₃; Deacetoxycefotaxime-d₃) is the deuterium labeled Cefetamet (HY-A0111). Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC₅₀ for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis .

HY-N7101S

Cefpodoxime proxetil-d7

Cefpodoxime proxetil-d₇ (U-76-d₇,252-d₇; CS-807-d₇) is the deuterium labeled Cefpodoxime Proxetil (HY-N7101). Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .

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