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Results for "

Cefotaxime

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

2

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-A0088A
    Cefotaxime
    5+ Cited Publications

    Cefotaxim; HR-756

    		 Beta-lactamase Bacterial Antibiotic Infection Inflammation/Immunology
    Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime
  • HY-W654101
    Cefotaxime-d3

    Cefotaxim-d3; HR-756-d3

    		 Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime-d3
  • HY-A0088
    Cefotaxime sodium
    5+ Cited Publications

    Cefotaxim sodium; HR-756 sodium

    		 Beta-lactamase Bacterial Antibiotic Infection
    Cefotaxime (Cefotaxim) sodium, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime sodium
  • HY-135394
    3-Desacetyl Cefotaxime lactone

    		Drug Metabolite Antibiotic Infection
    3-Desacetyl Cefotaxime lactone is the active metabolite of Cefotaxime. Cefotaxime sodium salt is a third-generation cephalosporin antibiotic.
    3-Desacetyl Cefotaxime lactone
  • HY-126129
    Desacetylcefotaxime

    		Bacterial Infection
    Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria .
    Desacetylcefotaxime
  • HY-A0088AR
    Cefotaxime (Standard)

    Cefotaxim (Standard); HR-756 (Standard)

    		 Beta-lactamase Reference Standards Bacterial Antibiotic Infection Inflammation/Immunology
    Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime (Standard)
  • HY-A0088R
    Cefotaxime sodium (Standard)

    Cefotaxim sodium (Standard); HR-756 sodium (Standard)

    		 Beta-lactamase Reference Standards Bacterial Antibiotic Infection
    Cefotaxime (sodium) (Standard) is the analytical standard of Cefotaxime (sodium). This product is intended for research and analytical applications. Cefotaxime (Cefotaxim) sodium, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime sodium (Standard)
  • HY-A0088S
    Cefotaxime-d3 sodium

    Cefotaxim-d3 sodium; HR-756-d3 sodium

    		 Isotope-Labeled Compounds Beta-lactamase Bacterial Antibiotic Infection
    Cefotaxime-d3 (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime-d3 sodium
  • HY-135394R
    3-Desacetyl Cefotaxime lactone (Standard)

    		Reference Standards Drug Metabolite Antibiotic Infection
    3-Desacetyl Cefotaxime lactone (Standard) is the analytical standard of 3-Desacetyl Cefotaxime lactone. This product is intended for research and analytical applications. 3-Desacetyl Cefotaxime lactone is the active metabolite of Cefotaxime. Cefotaxime sodium salt is a third-generation cephalosporin antibiotic.
    3-Desacetyl Cefotaxime lactone (Standard)
  • HY-116617R
    15-Keto Travoprost (Standard)

    15-Keto Fluprostenol isopropyl ester (Standard)

    		 Drug Metabolite Reference Standards Others
    Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    15-Keto Travoprost (Standard)
  • HY-126129R
    Desacetylcefotaxime (Standard)

    		Drug Metabolite Reference Standards Bacterial Infection
    Desacetylcefotaxime (Standard) is the analytical standard of Desacetylcefotaxime. This product is intended for research and analytical applications. Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria .
    Desacetylcefotaxime (Standard)
  • HY-150767
    KPC-2-IN-2

    		Bacterial Infection
    KPC-2-IN-2 (Compound 6c) is a potent Klebsiella pneumoniae carbapenemase (KPC-2) inhibitor (Ki=0.038 μM). KPC-2-IN-2 can enhance the activity of cefotaxime in KPC-2 expressing Escherichia coli .
    KPC-2-IN-2
  • HY-150766
    KPC-2-IN-1

    		Bacterial Infection
    KPC-2-IN-1, boronic acid derivative, is a potent KPC-2 inhibitor with Ki of 0.032 μM. KPC-2-IN-1 enhances the activity of cefotaxime in KPC-2 expressing E. coli. KPC-2-IN-1 exhibits well tolerated in human HEK-293 cells, which can be used for the study of E. coli resistance to β-lactam antibiotics .
    KPC-2-IN-1
  • HY-N7368
    Hibifolin

    		Adenosine Deaminase Bacterial Caspase Infection Neurological Disease Inflammation/Immunology Cancer
    Hibifolin is a flavonol glycoside that can be isolated from Helicteres isora. Hibifolin is an inhibitor of adenosine deaminase (ADA) (Ki = 49.92 μM). Hibifolin protects neurons against β-amyloid-induced neurotoxicity. Hibifolin possesses a potent protective activity against cell death induced by aggregated Aβ. Hibifolin can abolish Aβ-induced caspase-3 and caspase-7 activation. Hibifolin induces Akt phosphorylation in cortical neurons. Hibifolin is also a natural sortase A (SrtA) inhibitor (IC50 = 31.2 μM) through direct binding to SrtA protein. Hibifolin attenuates the pathogenic behavior of Staphylococcus aureus including adhesion, invasion, and biofilm formation. Hibifolin improves the survival of pneumonia induced by Staphylococcus aureus in mouse model and alleviates pathological damage. Hibifolin shows a synergistic antibacterial effect with Cefotaxime (HY-A0088A) .
    Hibifolin
  • HY-N7368R
    Hibifolin (Standard)

    		Reference Standards Adenosine Deaminase Bacterial Caspase Neurological Disease Inflammation/Immunology Cancer
    Hibifolin (Standard) is the analytical standard of Hibifolin. This product is intended for research and analytical applications. Hibifolin is a flavonol glycoside that can be isolated from Helicteres isora. Hibifolin is an inhibitor of adenosine deaminase (ADA) (Ki = 49.92 μM). Hibifolin protects neurons against β-amyloid-induced neurotoxicity. Hibifolin possesses a potent protective activity against cell death induced by aggregated Aβ. Hibifolin can abolish Aβ-induced caspase-3 and caspase-7 activation. Hibifolin induces Akt phosphorylation in cortical neurons. Hibifolin is also a natural sortase A (SrtA) inhibitor (IC50 = 31.2 μM) through direct binding to SrtA protein. Hibifolin attenuates the pathogenic behavior of Staphylococcus aureus including adhesion, invasion, and biofilm formation. Hibifolin improves the survival of pneumonia induced by Staphylococcus aureus in mouse model and alleviates pathological damage. Hibifolin shows a synergistic antibacterial effect with Cefotaxime (HY-A0088A) .
    Hibifolin (Standard)

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