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COX-2-IN-59

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-179125
    COX-2-IN-59

    		COX Bcl-2 Family Caspase Cancer
    COX-2-IN-59 is a potent and selective COX-2 inhibitor with an IC50 of 0.052 μM. COX-2-IN-59 exhibits >200-fold selectivity over COX-1 (IC50 = 11.16 μM). COX-2-IN-59 reduces COX-2 levels, induces cell cycle arrest, and triggers apoptosis by increasing Bax expression, decreasing Bcl-2 levels, and activating caspase-3. COX-2-IN-59 can be used for the research of colon cancer .
    COX-2-IN-59

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