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NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p .
Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit(cAK) with an IC50 of 3.5 μM.
Cdk7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdk7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Ddr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ddr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
NG 52 (Standard) is the analytical standard of NG 52. This product is intended for research and analytical applications. NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p .
CCNH Human Pre-designed siRNA Set A contains three designed siRNAs for CCNH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cdk7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdk7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Ddr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ddr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
BS-181 dihydrochloride is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880 nM, 3000 nM and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 dihydrochloride inhibits a panel of cancer cells growth (IC50=11.5 μM-37.3 μM) and induces cell apoptosis. BS-181 dihydrochloride has the potential for the research of cancer therapy .
CDK7 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
DDR1 Human Pre-designed siRNA Set A contains three designed siRNAs for DDR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit(cAK) with an IC50 of 3.5 μM.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. MPF Protein, Human (HEK293, His) is expressed by HEK293 , with C-6*His labeled tag.
Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein, as cells overexpressing mesothelin have altered adhesive properties. Mesothelin is also a Megakaryocyte-potentiating factor (MPF) which potentiates megakaryocyte colony formation in vitro. Mesothelin may be related to cancer metastasis. Mesothelin Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Mesothelin protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.
The DDR1 protein is a fibrillar collagen receptor that coordinates key cellular processes including matrix remodeling, migration, differentiation, survival, and proliferation.Upon collagen binding, DDR1 activates signaling cascades involving SRC and MAP kinases, promoting matrix remodeling through MMP upregulation, promoting cell migration, wound healing, and tumor invasion.DDR1 Protein, Rat (HEK293, His) is the recombinant rat-derived DDR1 protein, expressed by HEK293 , with C-His labeled tag.
The DDR1 protein is a tyrosine kinase and cell surface receptor for fibrillar collagen that tightly regulates cell attachment and affects extracellular matrix processes. Upon collagen binding, DDR1 initiates a signaling cascade involving SRC, activating MAP kinase. DDR1 Protein, Human (HEK293, His) is the recombinant human-derived DDR1 protein, expressed by HEK293 , with C-His labeled tag.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. MPF Protein, Human (HEK293, Fc) is expressed by HEK293 , with C-hFc labeled tag.
Together with its regulatory partners CCNH and MNAT1, CDK7 functions as an important serine/threonine kinase in cell cycle regulation and RNA polymerase II-mediated transcription. As the catalytic subunit of the CDK-activated kinase (CAK) complex, CDK7 plays a key role in activating CDK1/cyclin-B and CDK2/cyclin during cell cycle transitions. CDK7 Protein, Human (Sf9, GST) is the recombinant human-derived CDK7, expressed by Sf9 insect cells, with GST labeled tag. The total length of CDK7 Protein, Human (Sf9, GST) is 346 a.a..
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. MPF Protein, Human (Biotinylated, HEK293, His) is expressed by HEK293 , with C-His labeled tag.
The DDR1 protein is a fibrillar collagen receptor that coordinates key cellular processes including matrix remodeling, migration, differentiation, survival, and proliferation.Upon collagen binding, DDR1 activates signaling cascades involving SRC and MAP kinases, promoting matrix remodeling through MMP upregulation, promoting cell migration, wound healing, and tumor invasion.DDR1 Protein, Rat (HEK293, hFc) is the recombinant rat-derived DDR1 protein, expressed by HEK293 , with C-hFc labeled tag.
The DDR1 protein is a fibrillar collagen receptor that coordinates key cellular processes including matrix remodeling, migration, differentiation, survival, and proliferation. Upon collagen binding, DDR1 activates signaling cascades involving SRC and MAP kinases, promoting matrix remodeling through MMP upregulation, promoting cell migration, wound healing, and tumor invasion. DDR1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived DDR1 protein, expressed by HEK293 , with C-hFc labeled tag.
The DDR1 protein is a fibrillar collagen receptor that coordinates key cellular processes including matrix remodeling, migration, differentiation, survival, and proliferation. Upon collagen binding, DDR1 activates signaling cascades involving SRC and MAP kinases, promoting matrix remodeling through MMP upregulation, promoting cell migration, wound healing, and tumor invasion. DDR1 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived DDR1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
The DDR1 protein is a fibrillar collagen receptor that coordinates key cellular processes including matrix remodeling, migration, differentiation, survival, and proliferation. Upon collagen binding, DDR1 activates signaling cascades involving SRC and MAP kinases, promoting matrix remodeling through MMP upregulation, promoting cell migration, wound healing, and tumor invasion. DDR1 Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived DDR1 protein, expressed by HEK293 , with C-His labeled tag.
The DDR1 protein is a tyrosine kinase and cell surface receptor for fibrillar collagen that tightly regulates cell attachment and affects extracellular matrix processes. Upon collagen binding, DDR1 initiates a signaling cascade involving SRC, activating MAP kinase. DDR1 Protein, Human (sf9, His-GST) is the recombinant human-derived DDR1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein, as cells overexpressing mesothelin have altered adhesive properties. Mesothelin is also a Megakaryocyte-potentiating factor (MPF) which potentiates megakaryocyte colony formation in vitro. Mesothelin may be related to cancer metastasis. Mesothelin Protein, Human (303a.a, HEK293, His) is the recombinant human-derived Mesothelin protein, expressed by HEK293 , with C-6*His labeled tag.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. Mesothelin Protein, Human (HEK293, hFc) is the recombinant human-derived Mesothelin, expressed by HEK293 , with C-hFc labeled tag.
Mesothelin Protein, in its membrane-anchored forms, is implicated in cellular adhesion, suggesting a potential role in mediating cell interactions. Additionally, Megakaryocyte-potentiating factor (MPF) enhances megakaryocyte colony formation, indicating its involvement in the development of these specialized blood cell colonies. Mesothelin Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Mesothelin protein, expressed by HEK293 , with C-His labeled tag.
Mesothelin Protein, in its membrane-anchored forms, is implicated in cellular adhesion, suggesting a potential role in mediating cell interactions. Additionally, Megakaryocyte-potentiating factor (MPF) enhances megakaryocyte colony formation, indicating its involvement in the development of these specialized blood cell colonies. Mesothelin Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived Mesothelin protein, expressed by HEK293 , with C-hFc labeled tag.
Mesothelin Protein, in its membrane-anchored forms, is implicated in cellular adhesion, suggesting a potential role in mediating cell interactions. Additionally, Megakaryocyte-potentiating factor (MPF) enhances megakaryocyte colony formation, indicating its involvement in the development of these specialized blood cell colonies. Mesothelin Protein, Cynomolgus (Biotinylated, HEK293, His) is the recombinant cynomolgus-derived Mesothelin protein, expressed by HEK293 , with C-His labeled tag.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. Mesothelin Protein, Human (HEK293, His-Avi) is the recombinant human-derived Mesothelin protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. Mesothelin Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived Mesothelin protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. FITC-Labeled Mesothelin Protein, Human (HEK293, Fc) is the recombinant human-derived FITC-Labeled Mesothelin protein, expressed by HEK293 , with C-hFc labeled tag.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. Mesothelin Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived Mesothelin protein, expressed by HEK293 , with C-hFc labeled tag.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. FITC-Labeled Mesothelin Protein, Human (HEK293, His-Avi) is the recombinant human-derived FITC-Labeled Mesothelin protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Mesothelin Protein, in its membrane-anchored forms, is implicated in cellular adhesion, suggesting a potential role in mediating cell interactions. Additionally, Megakaryocyte-potentiating factor (MPF) enhances megakaryocyte colony formation, indicating its involvement in the development of these specialized blood cell colonies. Mesothelin Protein, Mouse (Biotinylated, 303a.a, HEK293, His) is the recombinant mouse-derived Mesothelin protein, expressed by HEK293 , with C-His labeled tag.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. Mesothelin Protein, Human (285a.a, HEK293, Fc) is the recombinant human-derived Mesothelin protein, expressed by HEK293 , with N-hFc labeled tag.
Mesothelin Protein, especially in its membrane-anchored forms, potentially mediates cellular adhesion, implicating its role in cell interactions. Furthermore, the associated Megakaryocyte-potentiating factor (MPF) actively enhances in vitro megakaryocyte colony formation, indicating its participation in fostering specialized blood cell colonies' development. Mesothelin Protein, Human (112a.a, Biotinylated, HEK293, His, Avi) is the recombinant human-derived Mesothelin protein, expressed by HEK293, with C-Avi and C-His labeled tag.
The DDR1 protein is a tyrosine kinase and cell surface receptor for fibrillar collagen that tightly regulates cell attachment and affects extracellular matrix processes. Upon collagen binding, DDR1 initiates a signaling cascade involving SRC, activating MAP kinase. DDR1 Protein, Human (HEK293, Fc) is the recombinant human-derived DDR1 protein, expressed by HEK293, with C-hFc labeled tag.
Together with its regulatory partners CCNH and MNAT1, CDK7 functions as an important serine/threonine kinase in cell cycle regulation and RNA polymerase II-mediated transcription. As the catalytic subunit of the CDK-activated kinase (CAK) complex, CDK7 plays a key role in activating CDK1/cyclin-B and CDK2/cyclin during cell cycle transitions. CDK7-CCNH-MNAT1 Protein, Human (sf9, His) is the recombinant human-derived CDK7-CCNH-MNAT1 protein, expressed by Sf9 insect cells , with N-His labeled tag. CDK7-CCNH-MNAT1 Protein, Human (sf9, His), has molecular weight of ~25 & 38 & 44 kDa, respectively.
Together with its regulatory partners CCNH and MNAT1, CDK7 functions as an important serine/threonine kinase in cell cycle regulation and RNA polymerase II-mediated transcription. As the catalytic subunit of the CDK-activated kinase (CAK) complex, CDK7 plays a key role in activating CDK1/cyclin-B and CDK2/cyclin during cell cycle transitions. CDK7-CCNH-MNAT1 Protein, Human (sf9, GST, His, Flag) is the recombinant human-derived CDK7-CCNH-MNAT1, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.
The DDR1 protein is a fibrillar collagen receptor that coordinates key cellular processes including matrix remodeling, migration, differentiation, survival, and proliferation. Upon collagen binding, DDR1 activates signaling cascades involving SRC and MAP kinases, promoting matrix remodeling through MMP upregulation, promoting cell migration, wound healing, and tumor invasion. DDR1 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived DDR1, expressed by HEK293, with C-6*His labeled tag. The total length of DDR1 Protein, Mouse (HEK293, C-His) is 395 a.a..
Mesothelin Antibody (YA1157) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1157), targeting Mesothelin. Mesothelin Antibody (YA1157) can be used for IHC-P experiment in human background.
Cyclin H Antibody (YA5224) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Cyclin H. It can be applicated for WB, IP assays, in the background of human.
Cdk7 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 39 kDa, targeting to Cdk7. It can be used for WB assays with tag free, in the background of Human.
PYK2 Antibody (YA682) is a non-conjugated and Mouse origined monoclonal antibody about 116 kDa, targeting to PYK2 (4B4). It can be used for WB,IHC-P assays with tag free, in the background of Human.
Mesothelin Antibody (YA5652) is a mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Mesothelin. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human.
PYK2 Antibody (YA5033) is a mouse-derived and non-conjugated monoclonal antibody, targeting to PYK2. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human.
PYK2 Antibody (YA5154) is a mouse-derived and non-conjugated monoclonal antibody, targeting to PYK2. It can be applicated for WB assays, in the background of human, mouse, dog, pig, rabbit.
PYK2 Antibody (YA5832) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PYK2. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.
DDR1 Antibody (YA4811) is a mouse-derived and non-conjugated monoclonal antibody, targeting to DDR1. It can be applicated for WB, ELISA assays, in the background of human.
Cdk7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdk7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Ddr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ddr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
CCNH Human Pre-designed siRNA Set A contains three designed siRNAs for CCNH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cdk7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdk7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Ddr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ddr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
CDK7 Human Pre-designed siRNA Set A contains three designed siRNAs for CDK7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
DDR1 Human Pre-designed siRNA Set A contains three designed siRNAs for DDR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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