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BS

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57

Inhibitors & Agonists

2

Fluorescent Dye

2

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1

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8

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4

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8

Isotope-Labeled Compounds

1

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3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14372

    CDK Cancer
    BS-194 is an orally active, selective and potent CDK inhibitor. BS-194 inhibits CDK2, CDK1, CDK5, CDK7, CDK9 (IC50s: 3, 30, 30, 250, and 90 nM respectively). BS-194 potently inhibits cancer cells proliferation. BS-194 can be used in the research of cancers like breast cancer, colon cancer .
    BS-194
  • HY-13266A
    BS-181 hydrochloride
    5 Publications Verification

    CDK Cancer
    BS-181 hydrochloride is a highly selective CDK7 inhibitor with IC50 of 21 nM, and > 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
    BS-181 hydrochloride
  • HY-124329
    BS3 Crosslinker
    1 Publications Verification

    ADC Linker Cancer
    BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    BS3 Crosslinker
  • HY-124329A
    BS3 Crosslinker disodium
    1 Publications Verification

    ADC Linker Cancer
    BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    BS3 Crosslinker disodium
  • HY-110368

    CDK Cancer
    BS-181 dihydrochloride is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880 nM, 3000 nM and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 dihydrochloride inhibits a panel of cancer cells growth (IC50=11.5 μM-37.3 μM) and induces cell apoptosis. BS-181 dihydrochloride has the potential for the research of cancer therapy .
    BS-181 dihydrochloride
  • HY-13266

    CDK Apoptosis Cancer
    BS-181 is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880, 3000 and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 inhibits a panel of cancer cells growth (IC50=11.5 μM-37.3 μM) and induces cell apoptosis. BS-181 has the potential for the research of cancer therapy .
    BS-181
  • HY-172619

    NF-κB Inflammation/Immunology
    BS-153 is a novel synthetic oxazolidinone agent with anti-inflammatory activities by blocking the activation of the NF-κB/PKCθ pathway. BS-153 inhibits the expression levels of iNOS and COX-2 and pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) on LPS-stimulated RAW264.7 cells .
    BS-153
  • HY-163687

    BS-7723 free base

    Biochemical Assay Reagents Cancer
    Tropirine (BS-7723 free base) is a radiosensitizer. Tropirine can be used in cancer research .
    Tropirine
  • HY-164022

    BS 7573a

    Others Others
    Acridorex (BS 7573a) is an anorectic agent .
    Acridorex
  • HY-124329AS

    Isotope-Labeled Compounds Others
    BS3 Crosslinker-d4 (disodium) is the deuterium labeled BS3 Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
    BS3 Crosslinker-d4 disodium
  • HY-130547S

    Isotope-Labeled Compounds Others
    BS2G Crosslinker-d4 (disodium) is the deuterium labeled BS2G Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
    BS2G Crosslinker-d4 disodium
  • HY-130547

    ADC Linker Cancer
    BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    BS2G Crosslinker disodium
  • HY-130547A

    DNA Alkylator/Crosslinker
    BS2G Crosslinker
  • HY-12489A

    Acid Red 112, BS

    Biochemical Assay Reagents Others
    Both Ponceau S and Ponceau BS are synthetic dyes commonly used in biological research. They are commonly used as protein stains to visualize proteins in western blots and other protein detection analyses. Ponceau S is a red dye, while Ponceau BS is a blue shade of the same dye. Both dyes bind to positively charged amino acid residues in proteins for easy visualization. However, Ponceau S is more commonly used due to its higher sensitivity.
    Ponceau S, BS
  • HY-111879

    SNIPERs Cancer
    Biotin-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and biotin, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase .
    Biotin-BS
  • HY-111878

    SNIPERs Cancer
    BzNH-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and benzoyl-amide, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase .
    BzNH-BS
  • HY-145583

    Hemay005

    Phosphodiesterase (PDE) Others Inflammation/Immunology
    Mufemilast (Heymay005) is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor (IC50 = 80-120 nM). Mufemilast modulates cytokines upregulated in Behςet’s syndrome (BS). Mufemilast displays a significant inhibitory effect on TNF-α, which is an important proinflammatory cytokine target in the disease process of psoriasis. Mufemilast can be studied in research for diseases such as rheumatoid arthritis, psoriasis and BS .
    Mufemilast
  • HY-A0095
    Flibanserin
    2 Publications Verification

    BIMT-17; BIMT-17BS

    5-HT Receptor Neurological Disease Cancer
    Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
    Flibanserin
  • HY-123360

    BIBW22BS

    Others Cancer
    BIBW 22 (BIBW22BS) is a dipyridamole analogue. BIBW 22 is a potent bifunctional modulator that affects p-glycoprotein and nucleoside transport in tumor cells .
    BIBW 22
  • HY-Z2775R

    Reference Standards
    (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity) (Standard) is the analytical standard of (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity). This product is intended for research and analytical applications.
    (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity) (Standard)
  • HY-N15332

    Bellissaponin BS2

    Others Cancer
    Virgaureasaponin 1 (Bellissaponin BS2) is a saponin that can be isolated from Bellis perennis. Virgaureasaponin 1 is cytotoxic against tumor cells (IC50: 4.6 μM for HL-60 cells) .
    Virgaureasaponin 1
  • HY-A0095R

    BIMT-17 (Standard); BIMT-17BS (Standard)

    Reference Standards 5-HT Receptor Neurological Disease Cancer
    Flibanserin (Standard) is the analytical standard of Flibanserin. This product is intended for research and analytical applications. Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
    Flibanserin (Standard)
  • HY-W753222

    Bedaquiline fumarate impurity 8-d6

    Isotope-Labeled Compounds Others
    (aS,bS)-rel-Bedaquiline-d6 (Bedaquiline fumarate impurity 8-d6) is the deuterium labeled (1S,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol (HY-14881E).
    (aS,bS)-rel-Bedaquiline-d6
  • HY-N14615

    Antibiotic Bacterial Infection
    Pyrisulfoxin A is an antibiotic found in Streptomyces callfornicus BS-75 .
    Pyrisulfoxin A
  • HY-N14951

    Antibiotic Bacterial Infection
    Pyrisulfoxin B is an antibiotic found in Streptomyces callfornicus BS-75 .
    Pyrisulfoxin B
  • HY-N10906

    Others Others
    (4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone .
    (4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one
  • HY-Z3061R

    Reference Standards
    (6aR,6bS,8aS,8bS,11aR,12aS,12bS)-8b-(2-Hydroxyacetyl)-6a,8a-dimethyl-10-propyl-6b,8,8a,8b,11a,12,12a,12b-octahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxole-4,7(2H,6aH)-dione (Budesonide Impurity) (Standard) is the analytical standard of (6aR,6bS,8aS,8bS,11aR,12aS,12bS)-8b-(2-Hydroxyacetyl)-6a,8a-dimethyl-10-propyl-6b,8,8a,8b,11a,12,12a,12b-octahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxole-4,7(2H,6aH)-dione (Budesonide Impurity). This product is intended for research and analytical applications.
    11-Keto Budesonide (Standard)
  • HY-Z8110R

    Reference Standards
    2-Oxo-2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-4a,6a,8-trimethyl-2-oxo-7-(propionyloxy)-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)ethyl propionate (Betamethasone Dipropionate Impurity) (Standard) is the analytical standard of 2-Oxo-2-((4aS,4bS,5aS,6aS,7R,8S,9aS,9bS)-4a,6a,8-trimethyl-2-oxo-7-(propionyloxy)-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)ethyl propionate (Betamethasone Dipropionate Impurity). This product is intended for research and analytical applications.
    Betamethasone dipropionate impurity 3 (Standard)
  • HY-B0590D

    (-)-TBZ; (3S,11BS)-TBZ; (3S,11BS)-Tetrabenazine

    Monoamine Transporter Neurological Disease
    (-)-Tetrabenazine ((-)-TBZ; compound 13) is an enantiomer of Tetrabenazine (HY-B0590). (+)-Tetrabenazine proves 3-fold more active than (-)-Tetrabenazine in inhibiting vesicular monoamine transporter 2 (VMAT2) .
    (-)-Tetrabenazine
  • HY-121525

    Ponceau BS

    Biochemical Assay Reagents Others
    Biebrich scarlet is an azo organosulfur dyes.
    Biebrich scarlet
  • HY-Z3488R

    Reference Standards
    (6aR,6bS,7S,8aS,8bS,11aR,12bR)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-6a,6b,7,8,8a,8b,11a,12b-octahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity) (Standard) is the analytical standard of (6aR,6bS,7S,8aS,8bS,11aR,12bR)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-6a,6b,7,8,8a,8b,11a,12b-octahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity). This product is intended for research and analytical applications.
    14,15-Dehydro budesonide (Standard)
  • HY-125131

    NO Synthase COX Inflammation/Immunology Cancer
    Buddlejasaponin IV (BS‐IV) exerts anti-inflammatory and cytotoxic effects against cancer cells .
    Buddlejasaponin IV
  • HY-W741425

    Isotope-Labeled Compounds Others
    21-O-Acetyl dexamethasone 9,11-epoxide-d5 is the deuterium labeled 2-((4aS,4bS,5aS,6aS,7R,8R,9aS,9bS)-7-Hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl acetate (Dexamethasone Acetate Impurity) (HY-Z8003).
    21-O-Acetyl dexamethasone 9,11-epoxide-d5
  • HY-75405R

    Reference Standards
    rel-(3aR,12bS)-11-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one (Standard) is the analytical standard of rel-(3aR,12bS)-11-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one. This product is intended for research and analytical applications.
    Asenapine impurity 1 (Standard)
  • HY-A0095B

    BIMT-17 hydrochloride; BIMT-17BS hydrochloride

    5-HT Receptor Dopamine Receptor Neurological Disease
    Flibanserin hydrochloride (BIMT-17 hydrochloride) is an orally active 5-HT1A receptor agonist and 5-HT2A receptor antagonist with binding affinities Ki of 1 nM and 49 nM, respectively. Flibanserin hydrochloride also binds to dopamine D4 receptors with a Ki of 4-24 nM. Flibanserin hydrochloride has antidepressant and anxiolytic effects and can be used in the study of hypoactive sexual desire disorder (HSDD) .
    Flibanserin hydrochloride
  • HY-10095A
    Olcegepant hydrochloride
    Maximum Cited Publications
    37 Publications Verification

    BIBN-4096 hydrochloride; BIBN4096BS hydrochloride

    CGRP Receptor Neurological Disease
    Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP .
    Olcegepant hydrochloride
  • HY-10095
    Olcegepant
    Maximum Cited Publications
    37 Publications Verification

    BIBN-4096; BIBN 4096BS

    CGRP Receptor Neurological Disease
    Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP .
    Olcegepant
  • HY-105000S1

    Isotope-Labeled Compounds Others
    trans-Dihydro Tetrabenazine-d7 is deuterium labeled (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol.
    trans-Dihydro Tetrabenazine-d7
  • HY-W016510

    Biochemical Assay Reagents Drug Intermediate Others
    Benzenesulfonate sodium is the sodium salt of Benzenesulfonic acid. Benzenesulfonate sodium facilitates the identification of -SO3H and -SO3 - vibrational bands in compounds in Raman spectroscopy. Benzenesulfonate sodium was used in the synthesis of 1-Butyl-3-propanenitrile imidazolium benzenesulfonate [C2CN Bim]BS .
    Benzenesulfonate sodium
  • HY-N2203

    Others Others
    Vitexin2''-O-p-coumarate is isolated from fenugreek seeds. Vitexin2''-O-p-coumarate strongly promotes 2BS cell proliferation induced by H2O2 .
    Vitexin2''-O-p-coumarate
  • HY-163882

    Bacterial DNA/RNA Synthesis Infection
    CUHK242 is a bacterial transcription inhibitor, with a MIC of 2 μg/mL for B. subtilis reporter strain BS2019. CUHK242 has antimicrobial activity against Staphylococcus aureus. CUHK242 can inhibit RNA synthesis in cells, thereby simultaneously reducing protein synthesis .
    CUHK242
  • HY-N12164

    Bacterial Fungal Infection
    Linearmycin B is an antibacterial and antifungal agent. Linearmycin B shows activity against Bacillus subtilis (Bs), Staphylococcus aureus (Sa). Candida albicans (Ca), and Saccharomyces cerevisiae (Sc), with MIC values of 0.097, 1.5, 0.0008, and 0.0002 μg/mL, respectively .
    Linearmycin B
  • HY-119022

    Bacterial Infection
    MAC-0547630 is a potent inhibitor of undecaprenyl diphosphate synthase (UppS), with IC50s of 0.05 μM and 1.6 μM for UppS BS and UppS BA, respectively. MAC-0547630 is active against B. subtilis in vitro (MIC 0.1 ng/mL) .
    MAC-0547630
  • HY-P5790

    Sodium Channel Neurological Disease
    μ-TRTX-Hd1a, a spider venom, is a selective NaV 1.7 inhibitor. μ-TRTX-Hd1a is a gating modifier that inhibits human NaV 1.7 by interacting with the S3b-S4 paddle motif in channel domain II .
    μ-TRTX-Hd1a
  • HY-RS05608

    Small Interfering RNA (siRNA) Others

    GP1BB Human Pre-designed siRNA Set A contains three designed siRNAs for GP1BB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GP1BB Human Pre-designed siRNA Set A
    GP1BB Human Pre-designed siRNA Set A
  • HY-RS01520

    Small Interfering RNA (siRNA) Others

    BLM Human Pre-designed siRNA Set A contains three designed siRNAs for BLM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    BLM Human Pre-designed siRNA Set A
    BLM Human Pre-designed siRNA Set A
  • HY-163523

    Microtubule/Tubulin Cancer
    PYRIB-SO 2 is a potent antimitotic agent. PYRIB-SO 2 shows antiproliferative activity and induces cell cycle arrest at G2/M phase. PYRIB-SO 2 reduces and disruptes microtubule structures. PYRIB-SO 2 binds to the colchicine-binding site (C-BS) of α, β-tubulin .
    PYRIB-SO 2
  • HY-W016510R

    Reference Standards Biochemical Assay Reagents Drug Intermediate Others
    Benzenesulfonate (sodium) (Standard) is an analytical standard for Benzenesulfonate sodium (HY-W016510). This product is intended for research and analytical applications. Benzenesulfonate sodium is the sodium salt of Benzenesulfonic acid. Benzenesulfonate sodium facilitates the identification of -SO3H and -SO3 - vibrational bands in compounds in Raman spectroscopy. Benzenesulfonate sodium was used in the synthesis of 1-Butyl-3-propanenitrile imidazolium benzenesulfonate [C2CN Bim]BS .
    Benzenesulfonate sodium (Standard)
  • HY-N2203A

    Others Others
    Vitexin2''-O-p-trans-coumarate is a flavonoid, can be isolated from the Et acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum. Vitexin2''-O-p-trans-coumarate strongly promotes 2BS cell proliferation induced by H2O2 .
    Vitexin2''-O-p-trans-coumarate
  • HY-A0095A

    BIMT-17 hydrochloride (propan-2-ol) hydrate; BIMT-17BS hydrochloride (propan-2-ol) hydrate

    5-HT Receptor Neurological Disease Cancer
    Flibanserin (BIMT-17) hydrochloride (propan-2-ol) hydrate is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin hydrochloride (propan-2-ol) hydrate binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin hydrochloride (propan-2-ol) hydrate shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
    Flibanserin hydrochloride (propan-2-ol) hydrate

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