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Results for "

BE

" in MedChemExpress (MCE) Product Catalog:

20

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

6

Natural
Products

2

Recombinant Proteins

2

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-143259
    BE1218

    		LXR Cancer
    BE1218 is a liver X receptor (LXR) inverse agonist with IC50 values of 9 nM and 7 nM against LXRα and LXRβ, respectively .
    BE1218
  • HY-100685
    MS-444
    2 Publications Verification

    BE-34776

    		 Myosin Cancer
    MS-444 inhibits the activity of purified smooth muscle myosin light chain kinase (MLCK) with an IC50 value of 10 μM.
    MS-444
  • HY-167671
    BE-10988

    		Topoisomerase Cancer
    BE-10988 is a DNA topoisomerase inhibitor. BE-10988 inhibits the growth of Doxorubicin (HY-15142A)-resistant and vincristine-resistant P388 mouse leukemia cell lines by increasing the formation of DNA topoisomerase complexes .
    BE-10988
  • HY-N10155A
    BE-18591

    		Bacterial Cancer
    BE-18591 shows antimicrobial activity against gram-positive and some gram-negative bacteria. BE-18591 inhibited the growth of the MKN-45 cell line (IC50= 0.285 μg/mL) and the P388 cell line (IC50= 0.52 μg/mL) .
    BE-18591
  • HY-121783
    BE2254

    		Adrenergic Receptor Others
    BE2254 is a compound with antipyretic and metabolic activity, which has the activity of regulating the febrile response and metabolism. BE2254 can reduce the metabolic and febrile activity induced by lipopolysaccharide in febrile rabbits, suggesting that it may regulate body temperature by acting on the α1-adrenergic receptor mechanism.
    BE2254
  • HY-138211
    BE-26263

    		Estrogen Receptor/ERR Metabolic Disease Endocrinology
    BE-26263, an antiosteoporotic agent that can be isolated from Scedosporium apiospermum, possesses estrogenic effect .
    BE-26263
  • HY-170571
    BE2647

    		Mitochondrial Metabolism Metabolic Disease Inflammation/Immunology
    BE2647 is a selective inhibitor for mitochondrial pyruvate carrier (MPC) with an EC50 of 70 nM. BE2647 exhibits good metabolic stability in mouse liver microsomes. BE2647 can be used in research of metabolic diseases, non-alcoholic fatty liver disease (MASLD), or non-alcoholic steatohepatitis (MASH) .
    BE2647
  • HY-167860
    BE-12406B

    		Others Cancer
    BE-12406B is an antitumor agent that can be found in the culture broth of a streptomycete. BE-12406B can inhibit the growth of Vincristine (HY-N0488)-resistant or Doxorubicin (HY-15142A)-resistant P388 murine leukemia cell lines as well as their parent sensitive cell line .
    BE-12406B
  • HY-100980
    HEAT hydrochloride

    BE2254 hydrochloride

    		 Adrenergic Receptor Neurological Disease Cancer
    HEAT (BE2254) hydrochloride is a selective alpha 1 adrenergic receptor antagonist. HEAT hydrochloride, a phenethylamine derivative, shows pKis of 9, 9.1, and 8.57 for alpha 1a, alpha 1b and alpha 1c, respectively .
    HEAT hydrochloride
  • HY-W781265
    BE 24566B

    L-755,805

    		 Endothelin Receptor Bacterial Infection
    BE 24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger. It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs=1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/mL, respectively). BE 24566B is an endothelin (ET) receptor antagonist (IC50s=11 and 3.9 μM for ETA and ETB receptors, respectively).
    BE 24566B
  • HY-107301
    Dehydrosoyasaponin I

    Soyasaponin BE; DHS-I

    		 Potassium Channel Neurological Disease
    Dehydrosoyasaponin I (Soyasaponin Be;DHS-I), a triterpene glycoside, is a potent and reversible calcium-activated potassium (maxi-K) channels activator .
    Dehydrosoyasaponin I
  • HY-107300
    Dehydrosoyasaponin I methyl ester

    Soyasaponin BE methyl ester; DHS-I methyl ester

    		 Others Others
    Dehydrosoyasaponin I methyl ester (Soyasaponin Be methyl ester) is a saponin found in Trifolium alexandrinum .
    Dehydrosoyasaponin I methyl ester
  • HY-14789R
    (R)-Elagolix (Standard)

    		GnRH Receptor Nuclear Factor of activated T Cells (NFAT) Endocrinology Cancer
    (R)-Elagolix (Standard) is the analytical standard of (R)-Elagolix. This product is intended for research and analytical applications. Elagolix is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
    (R)-Elagolix (Standard)
  • HY-14789
    (R)-Elagolix

    NBI-56418

    		 GnRH Receptor Nuclear Factor of activated T Cells (NFAT) Endocrinology Cancer
    Elagolix is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
    (R)-Elagolix
  • HY-176783
    GNE-5152

    		Toll-like Receptor (TLR) Neurological Disease
    GNE-5152 is an orthosteric SARM1 base-exchange (BE) inhibitor. GNE-5152 sustainably activates SARM1 at subinhibitory concentrations under mildly activating conditions, and this synergistic adverse effect increases NAD consumption, induces axon degradation and neurodegeneration and releases neurofilament-light (NfL) in cortical neurons. GNE-5152 can be used for neurodegenerative diseases research .
    GNE-5152
  • HY-RS17248
    Pomc Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Pomc Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pomc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Pomc Mouse Pre-designed siRNA Set A
    Pomc Mouse Pre-designed siRNA Set A
  • HY-N8765
    Methyl 2-(5-acetyl-2,3-dihydrobenzofuran-2-yl)propenoate

    		Others Neurological Disease
    Methyl 2-(5-acetyl-2,3-dihydrobenzofuran-2-yl)propenoate can be isolated from roots of Microglossa Pyrifolia. Microglossa Pyrifolia roots has analgesic and hepatic activities .
    Methyl 2-(5-acetyl-2,3-dihydrobenzofuran-2-yl)propenoate
  • HY-P10395
    DP50

    		Opioid Receptor Neuropeptide FF Receptor Neurological Disease
    DP50 is a bifunctional compound that contains an opioid receptor (MOP) agonist and a neuropeptide FF receptor (NPFFR) antagonist. DP50 can be used in analgesia-related research .
    DP50
  • HY-150229
    306-N16B

    		Liposome Cancer
    306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .
    306-N16B
  • HY-120943
    K-111

    BM 17.0744

    		 PPAR Metabolic Disease
    K-111 (BM-170744) is an oral active PPAR alpha agonist. K-111 show efficacy in improving insulin resistance, reducing body weight, and ameliorating atherogenic dyslipidemia. K-111 can be used for study of type 2 diabetes, dyslipidaemia, obesity and the metabolic syndrome .
    K-111

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