Search Result
        
        
            
                Results for "
Angelica
" in MedChemExpress (MCE) Product Catalog:
            
         
        
        
            
                
            
            
            
            
            
            
            
            
                
            
            
            
                
                    1
Isotope-Labeled Compounds
 
                    
                 
            
            
            
            
         
        
            
            
                
                    
                    
                        
                            | Cat. No. | 
                            Product Name | 
                            Target | 
                            Research Areas | 
                            Chemical Structure | 
                        
                    
                    
                        
                            
                            - 
                                
                                    - HY-N0548
 
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                                                        Glutathione S-transferase
                                                    
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                                                        Cancer
                                                    
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                                                    α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes    .
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                                    - HY-N13219
 
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                                                        Others
                                                    
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                                                        Metabolic Disease
                                                    
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                                                | 
                                                    Angelica Extract is an angelica extract, and its components include: Ligustilide. Angelica Extract can effectively inhibit the differentiation of osteoclasts, regulate osteoclastogenesis and/or bone loss. Angelica Extract has the potential to be used in the study of various bone diseases caused by excessive bone resorption. .
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                            - 
                                
                                    - HY-N0548R
 
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                                                        Glutathione S-transferase
                                                    
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                                                        Cancer
                                                    
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                                                | 
                                                    α-Angelica lactone (Standard) is the analytical standard of α-Angelica lactone. This product is intended for research and analytical applications. α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes    .
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                                    - HY-N0401B
 
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                                    - HY-N12069
 
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                                                        Others
                                                    
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                                                        Inflammation/Immunology
                                                    
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                                                    Praeroside IV can be isolated from the roots of Angelica furcijuga. Praeroside IV can be used for research of D-GalN/LPS-induced liver injury .
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                                    - HY-N1527
 
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                                                     Quinovic acid 3-O-α-L-rhamnoside 
                                                 | 
                                                
                                                    
                                                        Others
                                                    
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                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Quinovic acid 3-O-α-L-rhamnopyranoside (Quinovic acid 3-O-α-L-rhamnoside) is glycoside derivative. Quinovic acid 3-O-α-L-rhamnopyranoside can be isolated from the root bark of Guettarda angelica .
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                                    - HY-N9507
 
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                                                        Apoptosis
                                                    
                                                        FGFR
                                                    
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                                                        Cancer
                                                    
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                                                | 
                                                    Picrasidine Q, an alkaloid component extracted from Angelica keiskei species, has the capacity of anti-cell transformation and anti-cancer. Picrasidine Q induces cell apoptosis and G1 phase arrest in human esophageal cancer cell lines, and directly inhibits FGFR2 kinase activity .
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                                    - HY-N12070
 
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                                                        Others
                                                    
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                                                        Cardiovascular Disease
                                                    
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                                                    11-O-β-D-glucopyranosyl thamnosmonin, a coumarin glucosides, can be isolated from the roots of Angelica apaensis. 11-O-β-D-glucopyranosyl thamnosmonin has weak inhibitory activity on the aggregation of rabbit platelets induced by PAF, AA, and ADP .
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                                    - HY-N9535A
 
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                                                        Drug Metabolite
                                                    
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                                                        Metabolic Disease
                                                    
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                                                | 
                                                    (R)-tert-OMe-byakangelicin is a kind of furanocoumarin, which has inhibitory activity to liver drug metabolizing enzyme (DME) activity. (R)-tert-OMe-byakangelicin can be isolated from immature fruits of Angelica sinensis  .
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                                    - HY-N1286
 
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                                                     3-Hydroxysenkyunolide A 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                | 
                                                    Senkyunolide G (3-Hydroxysenkyunolide A) is a natural product that can be isolated from Angelica sinensis .
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                                    - HY-N9364
 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                    Iso-oxypeucedanin is a coumarin found in Angelica dahurica.
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                                    - HY-N4273
 
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                                                     (±)-Heraclenin 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                | 
                                                    Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.
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                                    - HY-N4234
 
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                                    - HY-N3524
 
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                                    - HY-N2272
 
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                                    - HY-134573
 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                    Dihydropashanone is a Chalcones product that can be isolated from the roots of Angelica pubescens .
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                                    - HY-N4052A
 
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                                                        Bacterial
                                                    
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                                                        Infection
                                                    
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                                                | 
                                                    (±)-Heraclenol, a coumarin, is isolated from the fruits of Angelica lucida, and exhibits antibacterial activities .
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                                    - HY-N8923
 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                | 
                                                    Angelol H is a natural tcompound isolated from Angelica pubescens MAXIM. (Umbelliferae) .
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                            - 
                                
                                    - HY-N4052
 
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                                                        Bacterial
                                                    
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                                                        Infection
                                                    
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                                                    Heraclenol, a coumarin, is isolated from the fruits of Angelica lucida, and exhibits antibacterial activities .
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                                    - HY-N0947
 
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                                                     (-)-Praeruptorin B 
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                                                        Others
                                                    
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                                                        Inflammation/Immunology
                                                    
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                                                    (-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .
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                                    - HY-N15417
 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                    1,13-Tridecanolide is an odor compound that can be isolated from the angelica root .
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                                    - HY-N1350
 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                    Riligustilide (compound 2) is a kind of phthalide dimer. Riligustilide can be isolated from the radix of Angelica sinensis .
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                                    - HY-126754
 
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                                    - HY-N2623
 
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                                                     Prangenidin 
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                                                        Others
                                                    
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                                                        Cancer
                                                    
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                                                    Alloimperatorin (Prangenidin), a coumarin compound, is extracted from Angelica dahurica. Alloimperatorin (Prangenidin) has antitumor activity  .
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                                    - HY-N7034
 
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                                                        Others
                                                    
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                                                        Neurological Disease
                                                    
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                                                    Magnolioside, isolated from Angelica gigas Nakai (Umbelliferae), exhibits significant neuroprotective activities against glutamate-induced toxicity .
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                                    - HY-N0286
 
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                                    - HY-N0075
 
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                                                        Others
                                                    
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                                                        Metabolic Disease
                                                    
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                                                    (Rac)-Byakangelicin is a racemate of Byakangelicin mainly isolated from the genus Angelica. Byakangelicin is an aldose-reductase inhibitor with an IC50 value of 6.2 μM .
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                                    - HY-N4273R
 
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                                                     (±)-Heraclenin (Standard) 
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                                                        Reference Standards
                                                    
                                                        Others
                                                    
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                                                        Others
                                                    
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                                                    Oxyimperatorin (Standard) is the analytical standard of Oxyimperatorin. This product is intended for research and analytical applications. Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.
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                                    - HY-N0825
 
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                                    - HY-N2276
 
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                                                        Others
                                                    
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                                                        Inflammation/Immunology
                                                    
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                                                    Nodakenetin, isolated from Angelica decursiva, possesses antioxidant anti-inflammatory activities. Nodakenetin has the potential to be an antiarthritic and nerve tonic  .
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                                    - HY-W099617
 
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                                                     1-Decanoyl-rac-glycerol 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                    2,3-Dihydroxypropyl decanoate (1-Decanoyl-rac-glycerol) is a natural product that can be isolated from the root of Angelica dahurica .
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                                    - HY-N4322
 
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                                                        PKC
                                                    
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                                                        Inflammation/Immunology
                                                    
                                                        Cancer
                                                    
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                                                    Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities  .
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                                    - HY-N0947R
 
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                                                     (-)-Praeruptorin B (Standard) 
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                                                        Reference Standards
                                                    
                                                        Others
                                                    
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                                                        Inflammation/Immunology
                                                    
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                                                    (-)-Anomalin (Standard) is the analytical standard of (-)-Anomalin. This product is intended for research and analytical applications. (-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .
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                                    - HY-N4236
 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                | 
                                                    Angelol A is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model .
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                                    - HY-N0401
 
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                                    - HY-N4235
 
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                                                        Others
                                                    
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                                                        Inflammation/Immunology
                                                    
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                                                    Angelol B is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model .
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                                    - HY-N0708
 
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                                    - HY-N6892
 
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                                                        Others
                                                    
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                                                        Cancer
                                                    
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                                                    3'-O-Acetylhamaudol, isolated from Angelica polymorpha, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation .
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                            - 
                                
                                    - HY-N9532
 
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                                                     Anhydrobyakangelicin 
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                                                        Others
                                                    
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                                                        Cancer
                                                    
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                                                    Isobyakangelicol is a coumarin that can be found in the roots of Angelica dahurica. Isobyakangelicol inhibits the growth of HeLa and HepG2 cells, with IC50s of 70.04 μM and 17.97 μM .
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                                    - HY-N0286R
 
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                                                        Reference Standards
                                                    
                                                        Cholinesterase (ChE)
                                                    
                                                        Bacterial
                                                    
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                                                        Neurological Disease
                                                    
                                                        Cancer
                                                    
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                                                    Isoimperatorin (Standard) is the analytical standard of Isoimperatorin. This product is intended for research and analytical applications. Isoimperatorin is a methanolic extract of the roots of Angelica dahurica shows significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 μM.
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                                    - HY-N8856
 
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                                                        Others
                                                    
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                                                        Others
                                                    
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                                                    Angelol M,isolated from the roots of Angelica gigas Nakai, shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells .
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                                    - HY-N0825R
 
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                                                        Reference Standards
                                                    
                                                        Cholinesterase (ChE)
                                                    
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                                                        Inflammation/Immunology
                                                    
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                                                    Nodakenin (Standard) is the analytical standard of Nodakenin. This product is intended for research and analytical applications. Nodakenin is a major coumarin glucoside in the root of Angelica decusiva. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC50 of 84.7 μM  .
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                                    - HY-111588
 
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                                    - HY-N0377A
 
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                                                     (±)-4',7-Dihydroxyflavanone 
                                                 | 
                                                
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
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                                                        Cardiovascular Disease
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) is isolated from Angelica keiskei, a hardy perennial herb of the Umbelliferae family. (±)-Liquiritigenin promotes cell proliferation, has cytoprotective activity and reduces cytotoxicity, and also has antioxidant stress effects .
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                            - 
                                
                                    - HY-N0075R
 
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                                                        Reference Standards
                                                    
                                                        Others
                                                    
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                                                        Metabolic Disease
                                                    
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                                                | 
                                                    (Rac)-Byakangelicin (Standard) is the analytical standard of (Rac)-Byakangelicin. This product is intended for research and analytical applications. (Rac)-Byakangelicin is a racemate of Byakangelicin mainly isolated from the genus Angelica. Byakangelicin is an aldose-reductase inhibitor with an IC50 value of 6.2 μM .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N8366
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Phosphatase
                                                    
                                                 | 
                                                
                                                    
                                                        Endocrinology
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Alloisoimperatorin (Compound 5) is a phytoestrogen that can be isolated from Angelica dahurica. Alloisoimperatorin can induce alkaline phosphatase (AP) activity with an EC50 of 0.8 μg/mL. Alloisoimperatorin can be used in the study of hormone-dependent cancers and the alleviation of menopausal symptoms .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-148937
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        PI3K
                                                    
                                                        Akt
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Oroselol is a coumarin commonly found in a variety of plants, especially in the roots of angelica plants and the bark of cinnamon trees. Oroselol has potential medicinal properties, including anti-inflammatory, antioxidant and anti-tumor effects. Oroselol can be used in the production of fragrances, flavors and medicines
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N0708R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        NF-κB
                                                    
                                                        Bacterial
                                                    
                                                        Endogenous Metabolite
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Vanillic acid (Standard) is the analytical standard of Vanillic acid. This product is intended for research and analytical applications. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N8414
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            - 
                                
                                    - HY-N4322R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        PKC
                                                    
                                                 | 
                                                
                                                    
                                                        Inflammation/Immunology
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Decursinol angelate (Standard) is the analytical standard of Decursinol angelate. This product is intended for research and analytical applications. Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities  .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                            
                            
                                
                                    - HY-N10856
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy- can be isolated from Angelica dahurica stem, for the first time from a plant source .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-W778225
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Isotope-Labeled Compounds
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Vanillic acid- 13C6 is the  13C labeled isotope of Vanillic acid- 13C6(HY-N0708 ).Vanillic acid is a flavoring agent found in edible plants and fruits, and in the root of angelica. Vanillic acid inhibits NF-κB activation. It has anti-inflammatory and antimicrobial activities.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-W087444A
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol is an active constituent of the aerial parts of Angelica sinensis. (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol significantly inhibits the growth of Aeromonas hydrophila. Anticoagulative and antibiotic activities .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-165044
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     DG(18:3/0:0/18:3);  1,3-Dilinolenin 
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    1,3-Di-α-linolenoyl glycerol (DG(18:3/0:0/18:3)) is a compound mentioned in the study of the chemical composition of Angelica acutiloba root. A variety of compounds have been isolated from the root, some of which have affinity for 5-HT(7) receptors.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N2488
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                     7-Demethylsuberosin 
                                                 | 
                                                
                                                    
                                                        Calcium Channel
                                                    
                                                        NO Synthase
                                                    
                                                 | 
                                                
                                                    
                                                        Cardiovascular Disease
                                                    
                                                        Neurological Disease
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound found in Angelica gigas Nakai. Demethylsuberosin exerts antihypertensive effects by inhibiting the L-type CaV1.2 channel. Demethylsuberosin has antioxidant and anti-inflammatory activities. Demethylsuberosin also exhibits neuroprotective activities against glutamate-induced toxicity in primary cultured rat cortical cells   .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0747
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0074
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        COX
                                                    
                                                 | 
                                                
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory agent on airway inflammation .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N6022
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Others
                                                    
                                                 | 
                                                
                                                    
                                                        Metabolic Disease
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Byakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects . Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of agent-agent interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0747R
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N7204
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Monoamine Oxidase
                                                    
                                                        Dopamine β-hydroxylase
                                                    
                                                        Apoptosis
                                                    
                                                 | 
                                                
                                                    
                                                        Neurological Disease
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation . 4-Hydroxyderricin is promising for research of inflammatory diseases     .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N2110
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Akt
                                                    
                                                        Sirtuin
                                                    
                                                        Integrin
                                                    
                                                        STAT
                                                    
                                                        PI3K
                                                    
                                                        Apoptosis
                                                    
                                                        ERK
                                                    
                                                        PPAR
                                                    
                                                        PKC
                                                    
                                                        Toll-like Receptor (TLR)
                                                    
                                                        HIV
                                                    
                                                 | 
                                                
                                                    
                                                        Inflammation/Immunology
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus        .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N2110R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Akt
                                                    
                                                        Sirtuin
                                                    
                                                        Integrin
                                                    
                                                        STAT
                                                    
                                                        PI3K
                                                    
                                                        Apoptosis
                                                    
                                                        ERK
                                                    
                                                        PPAR
                                                    
                                                        PKC
                                                    
                                                        Toll-like Receptor (TLR)
                                                    
                                                        HIV
                                                    
                                                 | 
                                                
                                                    
                                                        Infection
                                                    
                                                        Cardiovascular Disease
                                                    
                                                        Neurological Disease
                                                    
                                                        Metabolic Disease
                                                    
                                                        Inflammation/Immunology
                                                    
                                                        Cancer
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Phellopterin (Standard) is the analytical standard of Phellopterin. Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                        
                 
            
            
            
            
            
            
            
            
            
            
            
            
            
            
            
                
                    
                        
                            | Cat. No. | 
                            Product Name | 
                            Category | 
                            Target | 
                            Chemical Structure | 
                        
                    
                    
                            
                                
                                    - HY-N2488
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0747
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0074
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N6022
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N0747R
 
                                    - 
                                        
                                    
 
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N7204
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Chalcones
                                                            
                                                        
                                                            
                                                            
                                                                Monophenols
                                                            
                                                        
                                                            
                                                            
                                                                Flavonoids
                                                            
                                                        
                                                            
                                                            
                                                                Phenols
                                                            
                                                        
                                                            
                                                            
                                                                Umbelliferae
                                                            
                                                        
                                                            
                                                            
                                                                Plants
                                                            
                                                        
                                                            
                                                            
                                                                Ondetia linearis Benth.
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Monoamine Oxidase
                                                    
                                                        Dopamine β-hydroxylase
                                                    
                                                        Apoptosis
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is an orally active, potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits dopamine β (DBH)-hydroxylase activity. 4-Hydroxyderricin has antidepressant activity, anti-allergic, anti-diabetic, anti-oxidant, and antitumor effects. 4-Hydroxyderricin promotes apoptosis and cell cycle arrest through regulating PI3K/AKT/mTOR pathway in hepatocellular cells. 4-Hydroxyderricin inhibits osteoclast formation and accelerates osteoblast differentiation . 4-Hydroxyderricin is promising for research of inflammatory diseases     .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N2110
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Classification of Application Fields
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Coumarins
                                                            
                                                        
                                                            
                                                            
                                                                Phenylpropanoids
                                                            
                                                        
                                                            
                                                            
                                                                Umbelliferae
                                                            
                                                        
                                                            
                                                            
                                                                Helogyne apaloidea Nutt.
                                                            
                                                        
                                                            
                                                            
                                                                Plants
                                                            
                                                        
                                                            
                                                            
                                                                Inflammation/Immunology
                                                            
                                                        
                                                            
                                                            
                                                                Disease Research Fields
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Akt
                                                    
                                                        Sirtuin
                                                    
                                                        Integrin
                                                    
                                                        STAT
                                                    
                                                        PI3K
                                                    
                                                        Apoptosis
                                                    
                                                        ERK
                                                    
                                                        PPAR
                                                    
                                                        PKC
                                                    
                                                        Toll-like Receptor (TLR)
                                                    
                                                        HIV
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus        .
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                            
                            
                                
                                    - HY-N2110R
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                    
                                                 | 
                                                
                                                    
                                                    
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Coumarins
                                                            
                                                        
                                                            
                                                            
                                                                Phenylpropanoids
                                                            
                                                        
                                                            
                                                            
                                                                Umbelliferae
                                                            
                                                        
                                                            
                                                            
                                                                Helogyne apaloidea Nutt.
                                                            
                                                        
                                                            
                                                            
                                                                Plants
                                                            
                                                        
                                                    
                                                     
                                                        
                                                     
                                                 | 
                                                
                                                    
                                                        Reference Standards
                                                    
                                                        Akt
                                                    
                                                        Sirtuin
                                                    
                                                        Integrin
                                                    
                                                        STAT
                                                    
                                                        PI3K
                                                    
                                                        Apoptosis
                                                    
                                                        ERK
                                                    
                                                        PPAR
                                                    
                                                        PKC
                                                    
                                                        Toll-like Receptor (TLR)
                                                    
                                                        HIV
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Phellopterin (Standard) is the analytical standard of Phellopterin. Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                            
                        
                        
                 
            
            
            
            
            
                
                    
                        
                            | Cat. No. | 
                            Product Name | 
                            Chemical Structure | 
                        
                    
                    
                        
                            
                            - 
                                
                                    - HY-W778225
 
                                    - 
                                        
                                            
                                                | 
                                                    
                                                 | 
                                            
                                            
                                                | 
                                                    Vanillic acid- 13C6 is the  13C labeled isotope of Vanillic acid- 13C6(HY-N0708 ).Vanillic acid is a flavoring agent found in edible plants and fruits, and in the root of angelica. Vanillic acid inhibits NF-κB activation. It has anti-inflammatory and antimicrobial activities.
                                                 | 
                                            
                                        
                                     
                                    - 
                                        
                                        
                                            
                                        
                                     
                                
                             
                        
                        
                    
                 
            
            
            
            
            
                
                
         
        
        
        
        
        
        
            
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