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Results for "

Ala-Ala-Ala

" in MedChemExpress (MCE) Product Catalog:

39

Inhibitors & Agonists

50

Peptides

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P3106

    (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-Alanyl-L-arginine amide Rhodamine 110

    Fluorescent Dye Others
    (Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.
    (Z-Ala-Ala-Ala-Ala)2Rh110
  • HY-P4210

    ALRN-6924; MP-4897

    MDM-2/p53 Cancer
    Sulanemadlin (ALRN-6924) is a potent and cell-permeating p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research .
    Sulanemadlin
  • HY-W013460

    Amino Acid Derivatives Others
    Ala-Ala-Ala is an alanine derivative .
    Ala-Ala-Ala
  • HY-P3558

    Amino Acid Derivatives Others
    Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met
    Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met
  • HY-P4350

    Elastase Others
    Suc-Ala-Ala-Ala-AMC is a peptide substrate of elastase or elastase-like .
    Suc-Ala-Ala-Ala-AMC
  • HY-P4353

    Bacterial Others
    D-{Ala-Ala-Ala} is a tripeptide. D-{Ala-Ala-Ala} binds to ristocetin to detect bacteria at low concentrations .
    D-{Ala-Ala-Ala}
  • HY-160714

    ADC Linker Cancer
    Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH (Compound IM-3) is a cleavable ADC linker .
    Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH
  • HY-P10546

    pAla

    Bacterial Infection
    Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research .
    Polyalanine peptide
  • HY-P1100

    HepArrest

    Thrombin Cardiovascular Disease
    PM102 (HepArrest) is a heparin antagonist that can reverses the anticoagulant effect of heparin. PM102 potently binds heparin (Kd = 36 nM) in vitro .
    PM102
  • HY-P3248

    Myelin basic protein (85-99) antagonist

    Biochemical Assay Reagents Inflammation/Immunology
    J5 peptide is an MBP inhibitor that competitively inhibits the binding of MBP85-99 to HLA-DR2. J5 peptide alleviates PLP139-151/MBP85-99-induced experimental autoimmune encephalomyelitis (EAE) in mice. J5 peptide can be used in research on inflammatory and immune diseases .
    J5 peptide
  • HY-P0305

    Prion protein (106-126)

    Prion Protein Infection
    PrP (106-126) is a peptide corresponding to the prion protein (PrP) amyloidogenic region, and its biochemical properties resemble the infectious form of prion protein.
    PrP (106-126)
  • HY-P5559

    PROTACs Cancer
    ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research .
    ND1-YL2
  • HY-145237
    BM213
    2 Publications Verification

    Complement System Apoptosis Reactive Oxygen Species (ROS) Cancer
    BM213 is a selective C5aR agonist, with an EC50 of 59 nM. BM213 specifically activates the C5a-C5aR1 axis, which in turn promotes neutrophil extracellular trap (NET) formation and exacerbates inflammatory responses. BM213 significantly induces ventricular dilationin, promotes myocardial ROS production, and induces cardiomyocyte apoptosis in rats. BM213 can be used for the study of myocardial ischemia/reperfusion (I/R) injury .
    BM213
  • HY-P11303

    MHC Infection
    PADRE peptide is a universal peptidic epitope. PADRE peptide binds to pan HLA-DR receptors, present on specific T cells. PADRE peptide can be inserted into trichodysplasia spinulosa-associated polyomavirus (TSPyV) viral protein 1 (VP1) or hamster polyomavirus (HaPyV)-derived VP1 for construction of chimeric virus-like particles (VLPs), therefore activating dendritic cells and T cells and inducing strong immune responses and. PADRE peptide can be used for the development of vaccines .
    PADRE peptide
  • HY-P1576

    Salt-inducible Kinase (SIK) AMPK Inflammation/Immunology
    AMARA peptide is a substrate for SIK and AMPK.
    AMARA peptide
  • HY-P10183

    Cys-CD36(139-155)

    Transmembrane Glycoprotein Inflammation/Immunology
    CD36 Peptide P (139-155), Cys conjugated is a Cys labelled CD36 Peptide, and can inhibit the immunoadsorption of CD36 by OKM5 .
    CD36 Peptide P (139-155), Cys conjugated
  • HY-P10562

    TMV Others
    BMV Gag-(7?25) is an arginine-rich peptide with cell-penetrating ability. BMV Gag-(7?25) can be used in drug delivery and gene therapy research .
    BMV Gag-(7−25)
  • HY-P6312

    Bacterial Infection
    ESAT6 Epitope is a known CD4+ T cell epitope in early secretory antigen target gene 6 (ESAT6) that binds to major histocompatibility complex MHC class I with nanometer affinity (IC50=180 nM). ESAT6 Epitope can be used to enhance BCG-induced anti-Mycobacterium tuberculosis cellular immunity .
    ESAT6 Epitope
  • HY-P10796

    MAPKAPK2 (MK2) Inflammation/Immunology
    YARA peptide, a cell-penetrating peptide, is a MK2 inhibitor. YARA-loaded nanoparticles decreases the levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α) in an ex vivo skin culture model. YARA peptide is promising for research of atopic dermatitis (AD) .
    YARA peptide
  • HY-P10218A
    MANS peptide TFA
    1 Publications Verification

    MARCKS PKC Inflammation/Immunology Cancer
    MANS peptide TFA is the TFA salt form of MANS peptide (HY-P10218). MANS peptide TFA is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .
    MANS peptide TFA
  • HY-P10218
    MANS peptide
    1 Publications Verification

    MARCKS PKC Inflammation/Immunology Cancer
    MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .
    MANS peptide
  • HY-P5588

    Fungal Infection
    Dermaseptin-S4 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S4
  • HY-P5587

    Fungal Infection
    Dermaseptin-S5 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S5
  • HY-P4977

    Tau Protein Neurological Disease
    Tau Peptide (74-102) (Exon 3/Insert 2 Domain) is aTau fragment.
    Tau Peptide (74-102) (Exon 3/Insert 2 Domain)
  • HY-P5708

    Dermaseptin b2

    Antibiotic Fungal Bacterial Infection
    Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .
    Adenoregulin
  • HY-P5594

    Fungal Infection
    Dermaseptin-S1 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S1
  • HY-P0263A

    Bacterial Fungal Infection
    Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .
    Dermaseptin TFA
  • HY-P5593

    Fungal Infection
    Dermaseptin-S2 is an antimicrobial peptide derived from frog skin against filamentous fungi .
    Dermaseptin-S2
  • HY-P0263

    Bacterial Fungal Antibiotic Infection
    Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration .
    Dermaseptin
  • HY-P4704A

    α-synuclein Neurological Disease
    α-Synuclein (61-95) (human) TFA is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) TFA can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD) .
    α-Synuclein (61-95) (human) TFA
  • HY-P4704

    α-synuclein Neurological Disease
    α-Synuclein (61-95) (human) is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD) .
    α-Synuclein (61-95) (human)
  • HY-P11219

    YAP Cancer
    TAT-PDHPS1 is a YAP inhibitor composed of the endogenous peptide PDHPS1 and the cell-penetrating peptide sequence TAT. PDHPS1 binds to protein phosphatase 2 phosphatase activator (PTPA), an essential activator of protein phosphatase 2A (PP2A), leading to increased YAP phosphorylation, which inactivates YAP and suppresses the expression of its downstream target genes. TAT-PDHPS1 is potentially useful in ovarian cancer research .
    TAT-PDHPS1
  • HY-P1858A

    CRFR Cardiovascular Disease Neurological Disease Endocrinology
    Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2 . Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in the medial amygdala regulate complex social dynamics .
    Urocortin III, mouse TFA
  • HY-P1858

    CRFR Cardiovascular Disease Neurological Disease Endocrinology
    Urocortin III, mouse is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2 . Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in the medial amygdala regulate complex social dynamics .
    Urocortin III, mouse
  • HY-P3019

    CRFR Cardiovascular Disease Neurological Disease Endocrinology
    Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III (human) preferentially binds and activates CRF-R2 and has a discrete central nervous system and peripheral distribution. Urocortin III (human) selectively binds to type 2 CRF receptors with Ki values of 13.5, 21.7, and >100 nM for mCRF2β, rCRF2α, and hCRF1, respectively. Urocortin III (human) mediates somatostatin-dependent negative feedback control of Insulin (human) (HY-P0035) secretion .
    Urocortin III (human)
  • HY-P2829

    CRFR Endocrinology
    Stresscopin (human) is a selective ligand of type 2 adrenocorticotropin-releasing hormone (CRH) receptors and can be used in the research of stress-related diseases .
    Stresscopin (human)
  • HY-P5917

    Vaejovis mexicanus peptide 24

    Potassium Channel Inflammation/Immunology Cancer
    Vm24-toxin (Vaejovis mexicanus peptide 24), a 36-residue peptide, is a potent and selective Kv1.3 blocker with a Kd of ~3 pM in lymphocytes. Vm24-toxin shows >1500-fold affinity for Kv1.3 over other assayed potassium channels. Vm24-toxin folds into a distorted cystine-stabilized α/β motif consisting of a single-turn α-helix and a three-stranded antiparallel β-sheet, stabilized by four disulfide bridges. Vm24-toxin attenuates the CD4 + effector memory T cell response to T cell receptor (TCR) stimulation .
    Vm24-toxin
  • HY-P11074

    Bacterial Infection
    Sakacin P is an antimicrobial peptide that targets Gram-positive bacteria (such as Listeria monocytogenes) and belongs to Class IIa bacteriocin. Sakacin P has almost no antimicrobial activity against Gram-negative bacteria. Sakacin P exerts its antimicrobial activity by interacting with bacterial cell membranes and destroying membrane integrity. Sakacin P can be used for the study of Listeria contamination and antimicrobial drugs in the food industry.
    Sakacin P
  • HY-P5917A

    Vaejovis mexicanus peptide 24 TFA

    Potassium Channel Inflammation/Immunology Cancer
    Vm24-toxin (Vaejovis mexicanus peptide 24) TFA, a 36-residue peptide, is a potent and selective Kv1.3 blocker with a Kd of ~3 pM in lymphocytes. Vm24-toxin TFA shows >1500-fold affinity for Kv1.3 over other assayed potassium channels. Vm24-toxin TFA folds into a distorted cystine-stabilized α/β motif consisting of a single-turn α-helix and a three-stranded antiparallel β-sheet, stabilized by four disulfide bridges. Vm24-toxin TFA attenuates the CD4 + effector memory T cell response to T cell receptor (TCR) stimulation .
    Vm24-toxin TFA

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