Search Result

Results for "

Ad5

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (2) Atg8/LC3 (1) Bacterial (1) Beclin1 (1) Caspase (1) DNA/RNA Synthesis (1) Drug Derivative (1) EBV (1) Estrogen Receptor/ERR (1) Glycosidase (1) HPV (1) HSV (1) Influenza Virus (1) Isotope-Labeled Compounds (4) JNK (1) mAChR (1) MicroRNA (4) Necroptosis (1) Nucleoside Antimetabolite/Analog (1) TNF Receptor (1)
By Research Areas:	Cancer (7) Infection (3) Neurological Disease (1)
Oligonucleotides:	miRNA mimics (1) miRNA agomirs (1) miRNA antagomirs (1) MicroRNAs (4) miRNA inhibitors (1)

Inhibitors & Agonists

Inhibitory Antibodies

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119098

GSK983	EBV HPV	Infection
GSK983 is a broad-spectrum antiviral agent. GSK983 inhibits the replication of adenovirus-5 (Ad-5) and polyoma virus SV40. GSK983 inhibits the growth of cell lines immortalized by EBV, HTLV1, HPV. GSK983 induces the expression of interferon-stimulated genes .

HY-106777

Cyclopentenylcytosine 1 Publications Verification CPEC; NSC 375575	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Apoptosis Necroptosis Influenza Virus HSV	Infection Cancer
Cyclopentenylcytosine (CPEC), a carbocyclic nucleoside analog of cytosine, is a potent inhibitor of CTP synthetase and causes depletion of CTP and dCTP pools. Cyclopentenylcytosine shows broad-spectrum (both DNA and RNA viruses) antiviral activity. Cyclopentenyl cytosine increases Gemcitabine (HY-17026) radiosensitisation in human pancreatic cancer cells. Cyclopentenylcytosine shows effective antiviral activity in the Ad5/NZW rabbit ocular replication model and shows anti-tumor activity in various tumor xenografts model. Cyclopentenylcytosine can be used for the study of infection and cancer .

HY-P991570

Zaptuzumab Ad5-10	TNF Receptor Apoptosis Caspase Atg8/LC3 Akt Beclin1 JNK	Cancer
Zaptuzumab (AD5-10) is a DR5-specific humanized monoclonal antibody that selectively binds to DR5 with high affinity. Zaptuzumab specifically induces cancer cell death by both caspase-apoptosis and autophagic cell death (ACD). Zaptuzumab activates both ADCC and CDC. Zaptuzumab induces ROS generation and GSH level reduction. Zaptuzumab shows a significant suppression of the tumor growth and good safety in various xenografts mice tumor models ^[5].

HY-13204S2

rel-Biperiden EP impurity A-d5	Isotope-Labeled Compounds mAChR	Neurological Disease
rel-Biperiden EP impurity A-d₅ is deuterium labeled Biperiden (hydrochloride).

HY-132380S

3-epi-Ochratoxin A-d5	Isotope-Labeled Compounds	Others
3-epi-Ochratoxin A-d₅ is the deuterium labeled 3-epi-Ochratoxin A .

HY-111311

NVC-422	Bacterial Drug Derivative	Infection
NVC-422 is a N-chlorotaurine analog, virucidal agent, antibacterial agent. NVC-422 exhibits virucidal activity against Ad5 by the oxidative inactivation of key viral proteins (fiber and hexon), leading to the loss of viral integrity and infectivity. NVC-422 is shown to be highly effective in killing all microbial strains tested, including antibiotic-resistant S. aureus and E. faecium. NVC-422 can be used in the research of adenoviral conjunctivitis .

HY-R01637

hsa-miR-548ad-5p mimic	MicroRNA	Cancer
hsa-miR-548ad-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-548ad-5p mimic hsa-miR-548ad-5p mimic

HY-RI01637

hsa-miR-548ad-5p inhibitor	MicroRNA	Cancer
hsa-miR-548ad-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-548ad-5p inhibitor hsa-miR-548ad-5p inhibitor

HY-R01637A

hsa-miR-548ad-5p agomir	MicroRNA	Cancer
hsa-miR-548ad-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-548ad-5p agomir hsa-miR-548ad-5p agomir

HY-RI01637A

hsa-miR-548ad-5p antagomir	MicroRNA	Cancer
hsa-miR-548ad-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-548ad-5p antagomir hsa-miR-548ad-5p antagomir

HY-B0723S2

Ospemifene-d5 FC-1271a-d₅	Isotope-Labeled Compounds Estrogen Receptor/ERR	Cancer
Ospemifene-d₅ (FC-1271a-d₅) is deuterium labeled Ospemifene. Ospemifene is a non-estrogen selective estrogen receptor modulator (SERM), with K_is of 380 and 410 nM for estrogen receptor α (ERα) and ERβ, respectively. Ospemifene can be used for the research of vaginal atrophy and breast cancer .

HY-W728096

Migalastat-d5 GR181413A-d₅ free base	Isotope-Labeled Compounds Glycosidase	Others
Migalastat-d₅ (GR181413A-d₅ (free base)) is deuterium labeled Migalastat. Migalastat (GR181413A free base) is an orally active α-galactosidase A molecular chaperone, with an IC₅₀ value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .

Cat. No.	Product Name	Target	Research Area

HY-P991570

Zaptuzumab Ad5-10	TNF Receptor Apoptosis Caspase Atg8/LC3 Akt Beclin1 JNK	Cancer
Zaptuzumab (AD5-10) is a DR5-specific humanized monoclonal antibody that selectively binds to DR5 with high affinity. Zaptuzumab specifically induces cancer cell death by both caspase-apoptosis and autophagic cell death (ACD). Zaptuzumab activates both ADCC and CDC. Zaptuzumab induces ROS generation and GSH level reduction. Zaptuzumab shows a significant suppression of the tumor growth and good safety in various xenografts mice tumor models ^[5].

Cat. No.	Product Name	Chemical Structure

HY-13204S2

rel-Biperiden EP impurity A-d5
rel-Biperiden EP impurity A-d₅ is deuterium labeled Biperiden (hydrochloride).

HY-132380S

3-epi-Ochratoxin A-d5
3-epi-Ochratoxin A-d₅ is the deuterium labeled 3-epi-Ochratoxin A .

HY-B0723S2

Ospemifene-d5
Ospemifene-d₅ (FC-1271a-d₅) is deuterium labeled Ospemifene. Ospemifene is a non-estrogen selective estrogen receptor modulator (SERM), with K_is of 380 and 410 nM for estrogen receptor α (ERα) and ERβ, respectively. Ospemifene can be used for the research of vaginal atrophy and breast cancer .

HY-W728096

Migalastat-d5
Migalastat-d₅ (GR181413A-d₅ (free base)) is deuterium labeled Migalastat. Migalastat (GR181413A free base) is an orally active α-galactosidase A molecular chaperone, with an IC₅₀ value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .

Migalastat-d5

Migalastat-d₅ (GR181413A-d₅ (free base)) is deuterium labeled Migalastat. Migalastat (GR181413A free base) is an orally active α-galactosidase A molecular chaperone, with an IC₅₀ value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81860

	Presenilin 2 Antibody (YA1605) Ad3LP; Ad5; E5-1; STM-2	WB, IP	Human, Mouse, Rat
	Presenilin 2 Antibody (YA1605) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Presenilin 2.

HY-P82133

	Phospho-Presenilin 2 (Ser330) Antibody (YA1878) Ad3LP; Ad5; E5-1; STM-2	WB	Human, Mouse, Rat
	Phospho-Presenilin 2 (Ser330) Antibody (YA1878) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Presenilin 2 (Ser330).

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-R01637

hsa-miR-548ad-5p mimic		MicroRNAs miRNA mimics
hsa-miR-548ad-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI01637

hsa-miR-548ad-5p inhibitor		MicroRNAs miRNA inhibitors
hsa-miR-548ad-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01637A

hsa-miR-548ad-5p agomir		MicroRNAs miRNA agomirs
hsa-miR-548ad-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01637A

hsa-miR-548ad-5p antagomir		MicroRNAs miRNA antagomirs
hsa-miR-548ad-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Name
Email *

	Sorry, but the email address you supplied was invalid.