2. Search Result
Search Result
Results for "

Acyl CoA synthetase

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

3

Natural
Products

3

Recombinant Proteins

5

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W015444
    2-Hydroxyoctanoic acid

    		Endogenous Metabolite Metabolic Disease
    2-Hydroxyoctanoic acid is a medium chain acyl-CoA synthetase inhibitor with a Ki of 500 μM .
    2-Hydroxyoctanoic acid
  • HY-136615
    5-Hydroxydecanoate sodium

    		Potassium Channel Neurological Disease
    5-Hydroxydecanoate sodium is a selective ATP-sensitive K + (KATP) channel blocker (IC50 of ~30 μM). 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity .
    5-Hydroxydecanoate sodium
  • HY-117651
    2-Fluoropalmitic acid

    		Acyltransferase Cancer
    2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines .
    2-Fluoropalmitic acid
  • HY-173432
    LIBX-A401

    		Small Interfering RNA (siRNA) Others
    LIBX-A401 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4) (IC50 = 0.38 μM). LIBX-A401 has selectivity for ACSL4 over ACSL3 (IC50 over 50 μM) and PPARγ (IC50 over 10 μM) .
    LIBX-A401
  • HY-141699
    FATP1-IN-1
    1 Publications Verification

    		 FATP Metabolic Disease
    FATP1-IN-1 (compound 5k) is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC50 values of 0.046 μM or 0.60 μM, respectively .
    FATP1-IN-1
  • HY-N6707
    Triacsin C
    5 Publications Verification

    WS 1228A; FR 900190

    		 Parasite Infection Cardiovascular Disease
    Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C exhibits highly inhibitory effect against rotavirus replication .
    Triacsin C
  • HY-148104
    ACSS2-IN-2
    1 Publications Verification

    		 Acetyl-CoA synthetase Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer .
    ACSS2-IN-2
  • HY-177705
    ACSL5-IN-2

    		Drug Derivative Metabolic Disease Cancer
    ACSL5-IN-2 (Compound B) is an Acyl CoA synthetase 5 (ACSL5) inhibitor. ACSL5-IN-2 can block the conversion of long-chain fatty acids (such as palmitic acid and oleic acid) into acyl-CoA, and intervene in the fatty acid metabolism pathway. ACSL5-IN-2 can inhibit cancer cells growth. ACSL5-IN-2 can be used for the research of cancer and metabolic disease, such as colon cancer and dysfunction-associated Steatohepatitis .
    ACSL5-IN-2
  • HY-177704
    ACSL5-IN-1

    		Drug Derivative Metabolic Disease Cancer
    ACSL5-IN-1 (Compound A) is an Acyl CoA synthetase 5 (ACSL5) inhibitor. ACSL5-IN-1 can block the conversion of long-chain fatty acids (such as palmitic acid and oleic acid) into acyl-CoA, and intervene in the fatty acid metabolism pathway. ACSL5-IN-1 can inhibit cancer cells growth. ACSL5-IN-1 can be used for the research of cancer and metabolic disease, such as colon cancer and dysfunction-associated Steatohepatitis .
    ACSL5-IN-1
  • HY-W015444R
    2-Hydroxyoctanoic acid (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    2-Hydroxyoctanoic acid (Standard) is the analytical standard of 2-Hydroxyoctanoic acid. This product is intended for research and analytical applications. 2-Hydroxyoctanoic acid is a medium chain acyl-CoA synthetase inhibitor with a Ki of 500 μM[1].
    2-Hydroxyoctanoic acid (Standard)
  • HY-175328
    LIBX-A403

    		Ferroptosis Neurological Disease Cancer
    LIBX-A403 (Compound 21) is a highly selective acyl-CoA synthetase long-chain family member 4 (ACSL4) inhibitor (IC50=0.049 μM). LIBX-A403 blocks ACSL4-mediated ferroptosis-promoting phospholipid remodeling. LIBX-A403 is promising for research of cancers (e.g., triple-negative breast cancer) and neurodegenerative diseases (e.g., Parkinson’s disease) .
    LIBX-A403

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: