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AZD8205

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-171689

    AZD 8205

    Antibody-Drug Conjugates (ADCs) Cancer
    Puxitatug samrotecan (AZD8205) is an antibody-drug conjugate (ADC) targeting B7-H4. Puxitatug samrotecan is composed of the Puxitatug (HY-P990059) antibody targeting B7-H4, randomly conjugated to the Puxitatug samrotecan drug-linker (HY-163487) by reducing inter-chain cysteines. Puxitatug samrotecan has anti-tumor activity and can be used in the study of cancers expressing B7-H4 .
    Puxitatug samrotecan
  • HY-163487

    AZD8205 drug-linker

    Drug-Linker Conjugates for ADC Cancer
    Puxitatug samrotecan drug-linker (AZD8205 drug-linker) is part of the anti-B7-H4 antibody-conjugated active molecule ADC (drug-linker conjugate for ADC). Puxitatug samrotecan drug-linker contains a degradable ADC linker and a topoisomerase I inhibitor Exatecan (HY-13631) .
    Puxitatug samrotecan drug-linker

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