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Results for "

ADA

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

3

Biochemical Assay Reagents

1

Inhibitory Antibodies

4

Natural
Products

2

Recombinant Proteins

2

Isotope-Labeled Compounds

1

Antibodies

6

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0855
    ADA

    		Biochemical Assay Reagents Others
    ADA is a biological buffer . ADA can serve as a chelator .
    ADA
  • HY-D0855A
    ADA disodium

    		Biochemical Assay Reagents Others
    ADA (disodium) is a buffer salt derived from ADA (adenosine deaminase) and is widely used in biochemical research, especially in the preparation of enzyme buffers.
    ADA disodium
  • HY-103160A
    EHNA hydrochloride
    4 Publications Verification

    		 Adenosine Deaminase Phosphodiesterase (PDE) Influenza Virus Infection Cardiovascular Disease Neurological Disease Cancer
    EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects .
    EHNA hydrochloride
  • HY-W129499
    ADA sodium

    		Biochemical Assay Reagents Others
    ADA (sodium) is a buffer.
    ADA sodium
  • HY-RS00258
    ADA Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ADA Human Pre-designed siRNA Set A contains three designed siRNAs for ADA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ADA Human Pre-designed siRNA Set A
    ADA Human Pre-designed siRNA Set A
  • HY-RS00259
    Ada Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ada Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ada gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ada Mouse Pre-designed siRNA Set A
    Ada Mouse Pre-designed siRNA Set A
  • HY-RS00260
    Ada Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ada Rat Pre-designed siRNA Set A contains three designed siRNAs for Ada gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ada Rat Pre-designed siRNA Set A
    Ada Rat Pre-designed siRNA Set A
  • HY-RS00261
    ADA2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ADA2 Human Pre-designed siRNA Set A contains three designed siRNAs for ADA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ADA2 Human Pre-designed siRNA Set A
    ADA2 Human Pre-designed siRNA Set A
  • HY-103160B
    EHNA

    		Adenosine Deaminase Phosphodiesterase (PDE) Influenza Virus Infection Cardiovascular Disease Neurological Disease Cancer
    EHNA is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects .
    EHNA
  • HY-P991440
    AMG-966

    		TNF Receptor Inflammation/Immunology
    AMG-966 is a human bispecific antibody (bsAb) targeting TNFSF15/TL1A & TNFα. AMG 966 restores the ability of the aglycosylated Fc domain to bind to FcγRIa and FcγRIIa, leading to the formation of antidrug antibodies (ADA). AMG-966 can be used in Crohn's disease and Ulcerative colitis research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
    AMG-966
  • HY-114175A
    Adenosine deaminase, Calf Spleen

    RnADA, Calf Spleen

    		 Adenosine Deaminase Inflammation/Immunology
    Adenosine deaminase, Calf Spleen is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively .
    Adenosine deaminase, Calf Spleen
  • HY-117260
    Coformycin

    		Adenosine Deaminase Bacterial Antibiotic Infection Cancer
    Coformycin, a nucleoside antibiotic, is a potent inhibitor of adenosine deaminase (ADA) from Streptomyces species. Coformycin possesses anti-tumor and anti-bacterial activity .
    Coformycin
  • HY-133216
    Bupirimate

    		Fungal Adenosine Deaminase Infection
    Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew .
    Bupirimate
  • HY-W011552
    2'-O-Methyladenosine

    		Endogenous Metabolite Cardiovascular Disease
    2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
    2'-O-Methyladenosine
  • HY-103159
    1-Deazaadenosine

    		Adenosine Deaminase Cancer
    1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders .
    1-Deazaadenosine
  • HY-103237
    L-Adenosine

    		Adenosine Deaminase Neurological Disease
    L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an Ki value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation .
    L-Adenosine
  • HY-133216R
    Bupirimate (Standard)

    		Reference Standards Fungal Adenosine Deaminase Infection
    Bupirimate (Standard) is the analytical standard of Bupirimate (HY-133216). This product is intended for research and analytical applications. Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew .
    Bupirimate (Standard)
  • HY-116578R
    Metopimazine (Standard)

    		Drug Derivative Inflammation/Immunology
    Metopimazine (Standard) is the analytical standard of Metopimazine. This product is intended for research and analytical applications. Metopimazine (EXP999) is a phenothiazine derivative used to prevent emesis during chemotherapy. Metopimazine belongs to the anti-dopaminergic anti-emetics (ADA) class. Metopimazine can be used for the research of gastroenteritis (GE) .
    Metopimazine (Standard)
  • HY-158009
    SGF29-IN-1

    		Others Cancer
    SGF29-IN-1 (Compound Cpd_DC60) is a selective inhibitor for Spt-Ada-Gcn5 acetyltransferase (SAGA)–associated factor 29 (SGF29)-Tudor domain. SGF29-IN-1 exhibits activity against leukemia .
    SGF29-IN-1
  • HY-P5201S
    VTSEGAGLQLQK-13C6,15N2

    		Isotope-Labeled Compounds Others
    VTSEGAGLQLQK- 13C6, 15N2 is the 13C and 15N labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA). VTSEGAGLQLQK can be used to bind anti-drug antibodies (ADA) in plasma and quantitatively analyze the therapeutic effect .
    VTSEGAGLQLQK-13C6,15N2
  • HY-W011552R
    2'-O-Methyladenosine (Standard)

    		Reference Standards Endogenous Metabolite Cardiovascular Disease
    2'-O-Methyladenosine (Standard) is the analytical standard of 2'-O-Methyladenosine. This product is intended for research and analytical applications. 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
    2'-O-Methyladenosine (Standard)
  • HY-W753672
    2'-O-Methyladenosine-d3

    		Isotope-Labeled Compounds Cardiovascular Disease
    2'-O-Methyl Adenosine-d3 is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities .
    2'-O-Methyladenosine-d3
  • HY-17377
    Vicriviroc maleate

    SCH-417690 maleate; SCH-D maleate

    		 CCR HIV Infection Endocrinology Cancer
    Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC90s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570).
    Vicriviroc maleate
  • HY-105017
    Evodenoson

    ATL 313; DE 112

    		 Adenosine Receptor Infection Inflammation/Immunology
    Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenoson’s primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenoson’s protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α) .
    Evodenoson
  • HY-137294
    BTPTT-4F

    Y6

    		 Endogenous Metabolite Others
    BTPTT-4F (Y6) is a non-fullerene acceptor-donor-acceptor (A-D-A) type small molecular acceptor (SMA) characterized by its flexible alkyl chains and centrally fused ring structure. Featuring a ladder-type electron-deficient core, BTPTT-4F can be effectively blended with PM6, showcasing significant potential for enhancing the performance of organic photovoltaic applications. Its tailored optical properties and adjustable electronic energy levels contribute to improved thermal and photochemical stability, making it a promising candidate for next-generation high-performance organic solar cells.
    BTPTT-4F
  • HY-N7368
    Hibifolin

    		Adenosine Deaminase Bacterial Caspase Infection Neurological Disease Inflammation/Immunology Cancer
    Hibifolin is a flavonol glycoside that can be isolated from Helicteres isora. Hibifolin is an inhibitor of adenosine deaminase (ADA) (Ki = 49.92 μM). Hibifolin protects neurons against β-amyloid-induced neurotoxicity. Hibifolin possesses a potent protective activity against cell death induced by aggregated Aβ. Hibifolin can abolish Aβ-induced caspase-3 and caspase-7 activation. Hibifolin induces Akt phosphorylation in cortical neurons. Hibifolin is also a natural sortase A (SrtA) inhibitor (IC50 = 31.2 μM) through direct binding to SrtA protein. Hibifolin attenuates the pathogenic behavior of Staphylococcus aureus including adhesion, invasion, and biofilm formation. Hibifolin improves the survival of pneumonia induced by Staphylococcus aureus in mouse model and alleviates pathological damage. Hibifolin shows a synergistic antibacterial effect with Cefotaxime (HY-A0088A) .
    Hibifolin
  • HY-N7368R
    Hibifolin (Standard)

    		Reference Standards Adenosine Deaminase Bacterial Caspase Neurological Disease Inflammation/Immunology Cancer
    Hibifolin (Standard) is the analytical standard of Hibifolin. This product is intended for research and analytical applications. Hibifolin is a flavonol glycoside that can be isolated from Helicteres isora. Hibifolin is an inhibitor of adenosine deaminase (ADA) (Ki = 49.92 μM). Hibifolin protects neurons against β-amyloid-induced neurotoxicity. Hibifolin possesses a potent protective activity against cell death induced by aggregated Aβ. Hibifolin can abolish Aβ-induced caspase-3 and caspase-7 activation. Hibifolin induces Akt phosphorylation in cortical neurons. Hibifolin is also a natural sortase A (SrtA) inhibitor (IC50 = 31.2 μM) through direct binding to SrtA protein. Hibifolin attenuates the pathogenic behavior of Staphylococcus aureus including adhesion, invasion, and biofilm formation. Hibifolin improves the survival of pneumonia induced by Staphylococcus aureus in mouse model and alleviates pathological damage. Hibifolin shows a synergistic antibacterial effect with Cefotaxime (HY-A0088A) .
    Hibifolin (Standard)

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