41BBL

By Targets:	CD19 (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990017

Englumafusp alfa CD19-4-1BBL; RO7227166; RG6076	CD19	Cancer
Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion construct comprised of a CD19-specific antibody domain fused to a trimerized extracellular domains of human *41BBL*. Englumafusp alfa promotes CD19-specific 4-1BB cross-linking on the surface of T and NK cells .

HY-RS17085

Tnfsf9 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tnfsf9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfsf9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tnfsf9 Mouse Pre-designed siRNA Set A Tnfsf9 Mouse Pre-designed siRNA Set A

HY-RS14830

TNFSF9 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TNFSF9 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFSF9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TNFSF9 Human Pre-designed siRNA Set A TNFSF9 Human Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area

HY-P990017

Englumafusp alfa CD19-4-1BBL; RO7227166; RG6076	CD19	Cancer
Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion construct comprised of a CD19-specific antibody domain fused to a trimerized extracellular domains of human *41BBL*. Englumafusp alfa promotes CD19-specific 4-1BB cross-linking on the surface of T and NK cells .

Recombinant Proteins Recommended:

Species:	Human (2) Mouse (4) Rat (2) Cynomolgus (2)
Tag:	His (4) Fc (6)
Source:	HEK293 (8) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P7446

	4-1BBL/TNFSF9 Protein, Mouse (HEK293, His) rMu4-1BB Ligand/TNFSF9, His; 4-1BBL; CD137L; 4-1BB Ligand; TNFSF9	Mouse	HEK293
	4-1BBL (4-1BB ligand) is a type II membrane protein of the TNF superfamily, is expressed on antigen-presenting cells. 4-1BB with 4-1BBL can induce T-cell expansion, cytokine induction, differentiation, and upregulation of anti-apoptotic genes as well as protect T cells from activation-induced cell death (AICD). 4-1BBL stimulates T cell proliferation and induces effective anti-tumor immune responses. 4-1BBL is an immunostimulant molecule that interacts with the 4-1BB high-affinity receptor during the antigen presentation, providing costimulatory signals to both CD4+ and CD8+ T cells through the activation of NF-kB, c-Jun, and p38 downstream pathways, triggering pleiotropic effects on the immune system. 4-1BBL/TNFSF9 Protein, Mouse (HEK293, His) is a recombinant protein with a N-Terminal His label, It consists of 206 amino acids (R104-E309) and is produced in HEK293 cells.

HY-P78069

	4-1BBL/TNFSF9 Trimer Protein, Human (Biotinylated, HEK293, Fc) 41BB Ligand; 4-1BB Ligand; 4-1BBL; CD137L; TNFSF9	Human	HEK293
	4-1BBL (4-1BB ligand) is a type II membrane protein of the TNF superfamily, is expressed on antigen-presenting cells. 4-1BB with 4-1BBL can induce T-cell expansion, cytokine induction, differentiation, and upregulation of anti-apoptotic genes as well as protect T cells from activation-induced cell death (AICD). 4-1BBL stimulates T cell proliferation and induces effective anti-tumor immune responses. 4-1BBL is an immunostimulant molecule that interacts with the 4-1BB high-affinity receptor during the antigen presentation, providing costimulatory signals to both CD4+ and CD8+ T cells through the activation of NF-kB, c-Jun, and p38 downstream pathways, triggering pleiotropic effects on the immune system. 4-1BBL/TNFSF9 Trimer Protein, Human (Biotinylated, HEK293, Fc) is a biotinylated recombinant protein with a N-Terminal Fc label, It consists of 184 amino acids (R71-E254) and is produced in HEK293 cells.

HY-P7113

	4-1BBL/TNFSF9 Protein, Human rHu4-1BBL/TNFSF9; CD137L	Human	E. coli
	4-1BBL (4-1BB ligand) is a type II membrane protein of the TNF superfamily, is expressed on antigen-presenting cells. 4-1BB with 4-1BBL can induce T-cell expansion, cytokine induction, differentiation, and upregulation of anti-apoptotic genes as well as protect T cells from activation-induced cell death (AICD). 4-1BBL stimulates T cell proliferation and induces effective anti-tumor immune responses. 4-1BBL is an immunostimulant molecule that interacts with the 4-1BB high-affinity receptor during the antigen presentation, providing costimulatory signals to both CD4+ and CD8+ T cells through the activation of NF-kB, c-Jun, and p38 downstream pathways, triggering pleiotropic effects on the immune system. 4-1BBL/TNFSF9 Protein, Human is a recombinant protein consisting of 184 amino acids (R71-E254) and is produced in E. coli.

HY-P76705

	4-1BBL/TNFSF9 Protein, Rat (HEK293, His) Tumor necrosis factor ligand superfamily member 9; CD137L; 4-1BB Ligand	Rat	HEK293
	4-1BBL (4-1BB ligand) is a type II membrane protein of the TNF superfamily, is expressed on antigen-presenting cells. 4-1BB with 4-1BBL can induce T-cell expansion, cytokine induction, differentiation, and upregulation of anti-apoptotic genes as well as protect T cells from activation-induced cell death (AICD). 4-1BBL stimulates T cell proliferation and induces effective anti-tumor immune responses. 4-1BBL is an immunostimulant molecule that interacts with the 4-1BB high-affinity receptor during the antigen presentation, providing costimulatory signals to both CD4+ and CD8+ T cells through the activation of NF-kB, c-Jun, and p38 downstream pathways, triggering pleiotropic effects on the immune system. 4-1BBL/TNFSF9 Protein, Rat (HEK293, His) is a recombinant protein with a N-Terminal His label, It consists of 203 amino acids (P106-G308) and is produced in HEK293 cells.

HY-P77287

	4-1BBL/TNFSF9 Protein, Cynomolgus (HEK293, Fc) Tumor necrosis factor ligand superfamily member 9; CD137L; 4-1BB Ligand	Cynomolgus	HEK293
	4-1BBL (4-1BB ligand) is a type II membrane protein of the TNF superfamily, is expressed on antigen-presenting cells. 4-1BB with 4-1BBL can induce T-cell expansion, cytokine induction, differentiation, and upregulation of anti-apoptotic genes as well as protect T cells from activation-induced cell death (AICD). 4-1BBL stimulates T cell proliferation and induces effective anti-tumor immune responses. 4-1BBL is an immunostimulant molecule that interacts with the 4-1BB high-affinity receptor during the antigen presentation, providing costimulatory signals to both CD4+ and CD8+ T cells through the activation of NF-kB, c-Jun, and p38 downstream pathways, triggering pleiotropic effects on the immune system. 4-1BBL/TNFSF9 Protein, Cynomolgus (HEK293, Fc) is a recombinant protein with a N-Terminal Fc label, It consists of 184 amino acids (R68-E251) and is produced in HEK293 cells.

HY-P700160AF

	Animal-Free 4-1BBL/TNFSF9 Protein, Mouse (His) 41BB Ligand; 4-1BB Ligand; 4-1BBL; CD137L; TNFSF9	Mouse	E. coli
	4-1BBL/TNFSF9 Protein, a cytokine, binds TNFRSF9, inducing proliferation in activated peripheral blood T-cells.It's implicated in activation-induced cell death (AICD) and contributes to cognate interactions between T-cells and B-cells/macrophages.Functioning as a homotrimer enhances its biological activity.Animal-Free 4-1BBL/TNFSF9 Protein, Mouse (His) is the recombinant mouse-derived animal-Free4-1BBL/TNFSF9 protein, expressed by E.coli , with C-His labeled tag.This product is for cell culture use only.

HY-P7447

	4-1BB/TNFRSF9 Protein, Mouse (HEK293, Fc, solution) rMu4-1BB/TNFRSF9, C-Fc; CD137; 4-1 BB; TNFRSF-9	Mouse	HEK293
	4-1BB (CD137; TNFRSF9), a receptor of TNFSF9/4-1BBL, belongs to the tumor necrosis factor (TNF) receptor superfamily. 4-1BB is helpful for T cell activation and development, and also induces peripheral mononuclear cell proliferation and migration to the tumor microenvironment. 4-1BB is also involved in enhancing Nrf2 and NF-κB pathway mediated apoptosis of endothelial cells. Mouse 4-1BB protein is a surface glycoprotein with a transmembrane domain (188-208 a.a.). 4-1BB/TNFRSF9 Protein, Mouse (HEK293, Fc, solution) is the extracellular part (V24-L187) of 4-1BB protein, produced by HEK293 cells with C-terminal Fc-tag.

HY-P704596

	4-1BBL/TNFSF9 Protein, Mouse (HEK293, Fc) rMu4-1BB Ligand/TNFSF9, His; 4-1BBL; CD137L; 4-1BB Ligand; TNFSF9	Mouse	HEK293
	4-1BBL/TNFSF9 Protein, a cytokine, binds TNFRSF9, inducing proliferation in activated peripheral blood T-cells. It's implicated in activation-induced cell death (AICD) and contributes to cognate interactions between T-cells and B-cells/macrophages. Functioning as a homotrimer enhances its biological activity. 4-1BBL/TNFSF9 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived 4-1BBL/TNFSF9 protein, expressed by HEK293, with C-hFc labeled tag.

HY-P76704

	4-1BBL/TNFSF9 Protein, Rat (HEK293, Fc) Tumor necrosis factor ligand superfamily member 9; CD137L; 4-1BB Ligand	Rat	HEK293
	4-1BBL (4-1BB ligand) is a type II membrane protein of the TNF superfamily, is expressed on antigen-presenting cells. 4-1BB with 4-1BBL can induce T-cell expansion, cytokine induction, differentiation, and upregulation of anti-apoptotic genes as well as protect T cells from activation-induced cell death (AICD). 4-1BBL stimulates T cell proliferation and induces effective anti-tumor immune responses. 4-1BBL is an immunostimulant molecule that interacts with the 4-1BB high-affinity receptor during the antigen presentation, providing costimulatory signals to both CD4+ and CD8+ T cells through the activation of NF-kB, c-Jun, and p38 downstream pathways, triggering pleiotropic effects on the immune system. 4-1BBL/TNFSF9 Protein, Rat (HEK293, Fc) is a recombinant protein with a N-Terminal Fc label, It consists of 203 amino acids (P106-G308) and is produced in HEK293 cells.

HY-P77288

	4-1BBL/TNFSF9 Protein, Cynomolgus (Biotinylated, HEK293, Fc) Tumor necrosis factor ligand superfamily member 9; CD137L; 4-1BB Ligand	Cynomolgus	HEK293
	4-1BBL (4-1BB ligand) is a type II membrane protein of the TNF superfamily, is expressed on antigen-presenting cells. 4-1BB with 4-1BBL can induce T-cell expansion, cytokine induction, differentiation, and upregulation of anti-apoptotic genes as well as protect T cells from activation-induced cell death (AICD). 4-1BBL stimulates T cell proliferation and induces effective anti-tumor immune responses. 4-1BBL is an immunostimulant molecule that interacts with the 4-1BB high-affinity receptor during the antigen presentation, providing costimulatory signals to both CD4+ and CD8+ T cells through the activation of NF-kB, c-Jun, and p38 downstream pathways, triggering pleiotropic effects on the immune system. 4-1BBL/TNFSF9 Protein, Cynomolgus (Biotinylated, HEK293, Fc) is a biotinylated recombinant protein with a N-Terminal Fc label, It consists of 184 amino acids (R68-E251) and is produced in HEK293 cells.

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HY-P84309

	4-1BBL Antibody (YA4006) CD137L; TNLG5A; 4-1BB-L	IHC-P, ICC/IF, FC, ELISA	Human
	4-1BBL Antibody (YA4006) is a mouse-derived and non-conjugated IgG2b antibody, targeting to TNFSF9. It can be applicated for IHC-P, ICC/IF, FC, ELISA assays, in the background of human.

HY-P84953

	4-1BBL Antibody TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL
	4-1BBL Antibody is a non-conjugated antibody, targeting to 4-1BBL/CD137L.

HY-P81584

	4-1BBL Antibody (YA1329) TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL	FC, ELISA	Human
	4-1BBL Antibody (YA1329) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1329), targeting 4-1BB Ligand. 4-1BBL Antibody (YA1329) can be used for FC, ELISA experiment in human background.

HY-P82571

	4-1BBL Antibody (YA2316) TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL	WB, IP	Human
	4-1BBL Antibody (YA2316) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2316), targeting 4 1BBL, with a predicted molecular weight of 27 kDa (observed band size: 25-32 kDa). 4-1BBL Antibody (YA2316) can be used for WB, IP experiment in human background.

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HY-RS17085

Tnfsf9 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Tnfsf9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfsf9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14830

TNFSF9 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TNFSF9 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFSF9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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