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Results for "

4’-Methylguanosine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Bacterial (1) Biochemical Assay Reagents (2) CD38 (1) CFTR (2) Cholecystokinin Receptor (1) DNA/RNA Synthesis (8) Drug Derivative (1) Endogenous Metabolite (11) Ferroportin (1) Isotope-Labeled Compounds (3) MMP (1) Nucleoside Antimetabolite/Analog (27) Orthopoxvirus (1) Vasopressin Receptor (1) Virus Protease (1)
By Research Areas:	Cancer (17) Infection (6) Inflammation/Immunology (3) Metabolic Disease (3)
Oligonucleotides:	Nucleotides and their Analogs (8) A (2) Nucleosides and their Analogs (17) Nucleoside Phosphoramidites (1) G (24) Cap Analogs (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113136

1-Methylguanosine 2 Publications Verification N1-Methylguanosine	Endogenous Metabolite	Cancer
1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker .

HY-113136S

*1-Methylguanosine-d3* N1-Methylguanosine-d₃	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
1-Methylguanosine-d₃ (N1-Methylguanosine-d₃) is deuterium labeled 1-Methylguanosine (HY-113136). 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker .

HY-111647

N2-Methylguanosine	Nucleoside Antimetabolite/Analog Endogenous Metabolite	Others
N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA .

HY-122524S

*7-Methylguanosine-d3*	Nucleoside Antimetabolite/Analog Endogenous Metabolite	Inflammation/Immunology
7-Methylguanosine-d₃ is the deuterium labeled 7-Methylguanosine . 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC₅₀ value of 87.8 ± 7.5 μM .

HY-122524

7-Methylguanosine 1 Publications Verification	Nucleoside Antimetabolite/Analog Endogenous Metabolite DNA/RNA Synthesis	Others
7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects .

HY-W091784

3'-O-Methylguanosine	Endogenous Metabolite Orthopoxvirus Nucleoside Antimetabolite/Analog	Infection
3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis .

HY-152615

4’-Methylguanosine	Nucleoside Antimetabolite/Analog	Others
4’-Methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-111647R

*N2-Methylguanosine* (Standard)**	Nucleoside Antimetabolite/Analog Endogenous Metabolite	Others
N2-Methylguanosine (Standard) is the analytical standard of N2-Methylguanosine (HY-111647). This product is intended for research and analytical applications. N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA .

HY-111647S1

*N2-Methylguanosine-d3*	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog Endogenous Metabolite	Others
N2-Methylguanosine-d₃ is deuterium labeled N2-Methylguanosine (HY-111647). N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA .

HY-154242

8-Methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
8-Methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W013260S1

*2'-O-Methylguanosine-d3*	Isotope-Labeled Compounds Apoptosis Nucleoside Antimetabolite/Analog	Others
2'-O-Methylguanosine-d₃ is deuterium labeled 2'-O-Methylguanosine (HY-W013260). 2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells.

HY-W013260

2'-O-Methylguanosine	Nucleoside Antimetabolite/Analog Apoptosis DNA/RNA Synthesis	Infection Cancer
2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells .

HY-128139

2'-C-Methylguanosine 2'-C-beta-Methylguanosine	Nucleoside Antimetabolite/Analog	Others
2'-C-Methylguanosine (2'-C-beta-Methylguanosine) is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-154406

2′-Deoxy-N-methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
2’-Deoxy-N2-methylguanosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154147

2’-Deoxy-N1-methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
2’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152593

3’-Deoxy-N1-methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
3’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-153251

*DMT-2'-O-Methylguanosine* phosphoramidite**	DNA/RNA Synthesis	Others
DMT-2'-O-Methylguanosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-173169

*7-Methylguanosine* 5′-monophosphate** 7-Methylguanylic acid; 7-Methyl-GMP; m7GMP	Nucleoside Antimetabolite/Analog	Others
7-Methylguanosine 5′-monophosphate (7-Methylguanylic acid) is a building block of nucleic acid .

HY-141472

*7-Methylguanosine* 5'-diphosphate sodium** 7-Methyl-GDP sodium; m7GDP sodium	Endogenous Metabolite	Others
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues .

HY-160693

*2′-O-Methylguanosine* 5′-monophosphate**	DNA/RNA Synthesis	Others
2′-O-Methylguanosine 5′-monophosphate is the nucleotide complex group (pGm) of the ribosome and is primarily used for DNA conjugation. Today's antibodies recognize pGm, in descending order of importance, as the parent base, the methylated ribose moiety, and the phosphate group. 2′-O-Methylguanosine 5′-monophosphate can also be used to prepare RNA vaccines as a 5′-terminal nucleotide to block the RNA molecule .

HY-172507

*3'-O-Methylguanosine-5'-diphosphate*	Biochemical Assay Reagents	Others
3'-O-Methylguanosine-5'-diphosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-152610

3′-C-Methylguanosine	Nucleoside Antimetabolite/Analog	Others
3′-C-Methylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-152652

5’(R)-C-Methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
5’(R)-C-Methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-172002

*3'-O-Methylguanosine-5'-O-triphosphate sodium* 3'-O-Methyl GTP sodium	Drug Derivative	Metabolic Disease
3'-O-Methylguanosine-5'-O-triphosphate (3'-O-Methyl GTP) sodium is a methylated derivative of Guanosine 5'-triphosphate (HY-W010737). 3'-O-Methylguanosine-5'-O-triphosphate has been used as a chain termination reagent in the preparation of early RNA polymerase II elongation intermediates.

HY-172512

*3'-O-Methylguanosine-5'-monophosphate* 3'-OMe-GMP	Biochemical Assay Reagents	Others
3'-O-Methylguanosine-5'-monophosphate (3'-OMe-GMP) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-152467

8-Aza-2’-beta-C-methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
8-Aza-2’-beta-C-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152428

3’-Deoxy-3’-α-C-methylguanosine	Nucleoside Antimetabolite/Analog	Others
3’-Deoxy-3’-α-C-methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-21286

N2-Isobutyryl-2'-O-methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
N2-Isobutyryl-2'-O-methylguanosine (N2-IBU-2'-OME-RG) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154482

N2-iso-Butyroyl-3’-O-methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
N2-iso-Butyroyl-3’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-152545

N1,N2-Dimethyl-2’-O-methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
N1,N2-Dimethyl-2’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-154483

N2-iso-Butyroyl-5’-O-(4,4’-dimethoxytrityl)-3’-O-methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
N2-iso-Butyroyl-5’-O-(4,4’-dimethoxytrityl)-3’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-152547

N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine	Nucleoside Antimetabolite/Analog	Cancer
N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-111648

6-O-Methyl Guanosine	Nucleoside Antimetabolite/Analog	Inflammation/Immunology
6-O-Methyl Guanosine is a modified nucleoside . 6-O-Methyl Guanosine (6-methylguanosine) inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line .

HY-21586B

*7-Methyl-guanosine-5'-triphosphate sodium* m7GTP sodium	Nucleoside Antimetabolite/Analog	Others
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-21586

*7-Methyl-guanosine-5'-triphosphate disodium* m7GTP disodium	Nucleoside Antimetabolite/Analog	Metabolic Disease
7-Methyl-guanosine-5'-triphosphate (m7GTP) disodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate disodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-145969A

β-S-ARCA triammonium	DNA/RNA Synthesis	Cancer
β-S-ARCA (triammonium) is a mRNA 7-methylguanosine (m ⁷G) cap analog carrying a phosphorothioate (PS) moiety. mRNA incorporating β-S-ARCA (triammonium) can prolong cellular half-life and increase protein expression. β-S-ARCA (triammonium) can be used in research of mRNA-based anti-cancer vaccines .

HY-145969

β-S-ARCA	DNA/RNA Synthesis	Others
β-S-ARCA is a mRNA 7-methylguanosine (m ⁷G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines .

HY-139100

*N7-Methyl-guanosine-5'-triphosphate-5'-adenosine* m7GpppA	DNA/RNA Synthesis	Infection
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-P10828

MAPI	Virus Protease	Infection Inflammation/Immunology
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .

HY-113137

N2,N2-Dimethylguanosine 3 Publications Verification	Endogenous Metabolite	Cancer
N2,N2-Dimethylguanosine is a methylated nucleoside present in RNA and a structural modification component of tRNA. N2,N2-Dimethylguanosine hinders reverse transcriptase-mediated cDNA synthesis and is one of the key modifications that affect sequencing efficiency in high-throughput RNA sequencing. N2,N2-Dimethylguanosine can selectively remove one of the methyl groups through AlkB mutant enzymes (such as D135S/L118V) and convert it into N2-methylguanosine, thereby reducing the hindrance to reverse transcription .

HY-160745

2'-O-methyladenosine 5'-phosphate	DNA/RNA Synthesis	Others
2'-O-methyladenosine 5'-phosphate is the nucleotide complex group of ribosomes and is mainly used for DNA conjugation. 2'-O-methyladenosine 5'-phosphate is used to prepare RNA vaccines and is the main part of the RNA molecule, while the 5'-end is blocked by 2'-O-Methylguanosine 5'-monophosphate .

HY-P1108A

Astressin 2B TFA	CFTR	Others
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B TFA antagonizes CRF2-mediated inhibition of gastric emptying .

HY-P1108

Astressin 2B	CFTR	Others
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B antagonizes CRF2-mediated inhibition of gastric emptying .

HY-P2592

Ro 23-7014	Cholecystokinin Receptor	Others
Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .

HY-P4521

*Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt*	MMP	Others
Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt is a MMP12 substrate, and can be used to detect MMP12 enzyme activity .

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .

HY-125628

Kahalalide A	Endogenous Metabolite	Infection
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

Cat. No.	Product Name	Target	Research Area

HY-P1108A

Astressin 2B TFA	CFTR	Others
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B TFA antagonizes CRF2-mediated inhibition of gastric emptying .

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-P10828

MAPI	Virus Protease	Infection Inflammation/Immunology
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .

HY-P4756

*N-(2-Carbamoyl-ethyl)-Val-Leu-anilide*	Peptides	Others
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1108

Astressin 2B	CFTR	Others
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B antagonizes CRF2-mediated inhibition of gastric emptying .

HY-P2592

Ro 23-7014	Cholecystokinin Receptor	Others
Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .

HY-P4521

*Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt*	MMP	Others
Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt is a MMP12 substrate, and can be used to detect MMP12 enzyme activity .

HY-125628

Kahalalide A	Endogenous Metabolite	Infection
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113136

1-Methylguanosine 2 Publications Verification N1-Methylguanosine	Infection Structural Classification Natural Products Other disease Classification of Application Fields Source classification Disease markers Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker .

HY-122524

7-Methylguanosine 1 Publications Verification	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Nucleoside Antimetabolite/Analog Endogenous Metabolite DNA/RNA Synthesis
7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects .

HY-W091784

3'-O-Methylguanosine	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Orthopoxvirus Nucleoside Antimetabolite/Analog
3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis .

HY-113137

N2,N2-Dimethylguanosine 3 Publications Verification	Structural Classification Natural Products Other disease Classification of Application Fields Source classification Disease markers Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
N2,N2-Dimethylguanosine is a methylated nucleoside present in RNA and a structural modification component of tRNA. N2,N2-Dimethylguanosine hinders reverse transcriptase-mediated cDNA synthesis and is one of the key modifications that affect sequencing efficiency in high-throughput RNA sequencing. N2,N2-Dimethylguanosine can selectively remove one of the methyl groups through AlkB mutant enzymes (such as D135S/L118V) and convert it into N2-methylguanosine, thereby reducing the hindrance to reverse transcription .

HY-A0248A

Polymyxin B1 1 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-111647R

*N2-Methylguanosine* (Standard)**	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Nucleoside Antimetabolite/Analog Endogenous Metabolite
N2-Methylguanosine (Standard) is the analytical standard of N2-Methylguanosine (HY-111647). This product is intended for research and analytical applications. N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA .

HY-141472

*7-Methylguanosine* 5'-diphosphate sodium** 7-Methyl-GDP sodium; m7GDP sodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues .

Cat. No.	Product Name	Chemical Structure

HY-113136S

*1-Methylguanosine-d3*
1-Methylguanosine-d₃ (N1-Methylguanosine-d₃) is deuterium labeled 1-Methylguanosine (HY-113136). 1-Methylguanosine is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker .

HY-122524S

*7-Methylguanosine-d3*
7-Methylguanosine-d₃ is the deuterium labeled 7-Methylguanosine . 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC₅₀ value of 87.8 ± 7.5 μM .

HY-111647S1

*N2-Methylguanosine-d3*
N2-Methylguanosine-d₃ is deuterium labeled N2-Methylguanosine (HY-111647). N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA .

Cat. No.	Product Name		Classification

HY-111647

N2-Methylguanosine		Nucleosides and their Analogs G
N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA .

HY-W013260

2'-O-Methylguanosine		Nucleosides and their Analogs G
2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells .

HY-154147

2’-Deoxy-N1-methylguanosine		Nucleosides and their Analogs G
2’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152615

4’-Methylguanosine		Nucleosides and their Analogs G
4’-Methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154242

8-Methylguanosine		Nucleosides and their Analogs G
8-Methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154406

2′-Deoxy-N-methylguanosine		Nucleosides and their Analogs G
2’-Deoxy-N2-methylguanosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152593

3’-Deoxy-N1-methylguanosine		Nucleosides and their Analogs G
3’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-153251

*DMT-2'-O-Methylguanosine* phosphoramidite**		Nucleoside Phosphoramidites G
DMT-2'-O-Methylguanosine phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.

HY-160693

*2′-O-Methylguanosine* 5′-monophosphate**		Nucleotides and their Analogs G
2′-O-Methylguanosine 5′-monophosphate is the nucleotide complex group (pGm) of the ribosome and is primarily used for DNA conjugation. Today's antibodies recognize pGm, in descending order of importance, as the parent base, the methylated ribose moiety, and the phosphate group. 2′-O-Methylguanosine 5′-monophosphate can also be used to prepare RNA vaccines as a 5′-terminal nucleotide to block the RNA molecule .

HY-172507

*3'-O-Methylguanosine-5'-diphosphate*		Nucleotides and their Analogs G
3'-O-Methylguanosine-5'-diphosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-152610

3′-C-Methylguanosine		Nucleosides and their Analogs G
3′-C-Methylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-152652

5’(R)-C-Methylguanosine		Nucleosides and their Analogs G
5’(R)-C-Methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-172002

*3'-O-Methylguanosine-5'-O-triphosphate sodium* 3'-O-Methyl GTP sodium		Nucleotides and their Analogs G
3'-O-Methylguanosine-5'-O-triphosphate (3'-O-Methyl GTP) sodium is a methylated derivative of Guanosine 5'-triphosphate (HY-W010737). 3'-O-Methylguanosine-5'-O-triphosphate has been used as a chain termination reagent in the preparation of early RNA polymerase II elongation intermediates.

HY-172512

*3'-O-Methylguanosine-5'-monophosphate* 3'-OMe-GMP		Nucleotides and their Analogs G
3'-O-Methylguanosine-5'-monophosphate (3'-OMe-GMP) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-152467

8-Aza-2’-beta-C-methylguanosine		Nucleosides and their Analogs G
8-Aza-2’-beta-C-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152428

3’-Deoxy-3’-α-C-methylguanosine		Nucleosides and their Analogs G
3’-Deoxy-3’-α-C-methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-21286

N2-Isobutyryl-2'-O-methylguanosine		Nucleosides and their Analogs G
N2-Isobutyryl-2'-O-methylguanosine (N2-IBU-2'-OME-RG) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154482

N2-iso-Butyroyl-3’-O-methylguanosine		Nucleosides and their Analogs G
N2-iso-Butyroyl-3’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-152545

N1,N2-Dimethyl-2’-O-methylguanosine		Nucleosides and their Analogs G
N1,N2-Dimethyl-2’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-154483

N2-iso-Butyroyl-5’-O-(4,4’-dimethoxytrityl)-3’-O-methylguanosine		Nucleosides and their Analogs G
N2-iso-Butyroyl-5’-O-(4,4’-dimethoxytrityl)-3’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-152547

N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine		Nucleosides and their Analogs G
N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .

HY-111648

6-O-Methyl Guanosine		Nucleosides and their Analogs G
6-O-Methyl Guanosine is a modified nucleoside . 6-O-Methyl Guanosine (6-methylguanosine) inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line .

HY-21586B

*7-Methyl-guanosine-5'-triphosphate sodium* m7GTP sodium		Nucleotides and their Analogs G
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-21586

*7-Methyl-guanosine-5'-triphosphate disodium* m7GTP disodium		Nucleotides and their Analogs G
7-Methyl-guanosine-5'-triphosphate (m7GTP) disodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate disodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-145969A

β-S-ARCA triammonium		Cap Analogs
β-S-ARCA (triammonium) is a mRNA 7-methylguanosine (m ⁷G) cap analog carrying a phosphorothioate (PS) moiety. mRNA incorporating β-S-ARCA (triammonium) can prolong cellular half-life and increase protein expression. β-S-ARCA (triammonium) can be used in research of mRNA-based anti-cancer vaccines .

HY-145969

β-S-ARCA		Cap Analogs
β-S-ARCA is a mRNA 7-methylguanosine (m ⁷G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines .

HY-139100

*N7-Methyl-guanosine-5'-triphosphate-5'-adenosine* m7GpppA		Nucleotides and their Analogs A
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-160745

2'-O-methyladenosine 5'-phosphate		Nucleotides and their Analogs A
2'-O-methyladenosine 5'-phosphate is the nucleotide complex group of ribosomes and is mainly used for DNA conjugation. 2'-O-methyladenosine 5'-phosphate is used to prepare RNA vaccines and is the main part of the RNA molecule, while the 5'-end is blocked by 2'-O-Methylguanosine 5'-monophosphate .

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