Search Result

Results for "

16:0(Alkyne)-18:1 PE

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (14) Biochemical Assay Reagents (22) Btk (1) Calcium Channel (1) DNA Stain (1) E3 Ligase Ligand-Linker Conjugates (4) Endogenous Metabolite (1) Fluorescent Dye (27) Histone Acetyltransferase (1) Integrin (1) Interleukin Related (2) Ligands for Target Protein for PROTAC (1) Liposome (2) Mitochondrial Metabolism (1) Oxidative Phosphorylation (1) Phosphatase (1) PROTAC Linkers (16) Ras (1) SARS-CoV (1) Somatostatin Receptor (1) TRP Channel (1)
By Research Areas:	Cancer (36) Cardiovascular Disease (1) Endocrinology (1) Infection (2) Inflammation/Immunology (5) Metabolic Disease (3)
Click Chemistry:	ADC Synthesis (6) Labeling and Fluorescence Imaging (20) DBCO (1) PROTAC Synthesis (16) BCN (1) Tetrazine (2) Alkynes (76)
Oligonucleotides:	Phospholipids (1) Cholesterol (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-151646

Alkyne-PEG5-SNAP Alkyne-PEG5-BG	ADC Linker	Others
Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151645

Alkyne-SNAP	ADC Linker	Others
Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .

HY-151705

Alkyne Cholesterol 1 Publications Verification	Liposome	Metabolic Disease
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-137042

Cyanine5 alkyne Alkyne-Cy5	Oxidative Phosphorylation Mitochondrial Metabolism	Cancer
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P6438

Alkyne-cRGD	Integrin	Others Cancer
Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD undergoes copper-catalyzed azide-alkyne cycloaddition reaction .

HY-131442

Alkyne-phenol 2 Publications Verification Alkyne tyramide; Alk-Ph	Biochemical Assay Reagents	Others
Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins . Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151790

Alkyne-SS-COOH	ADC Linker	Others
Alkyne-SS-COOH is a click chemistry reagent containing an *alkyne* group. Alkyne-SS-COOH can be used for the research of various biochemical .

HY-151665

Alkyne-PEG2-iodide	ADC Linker	Others
Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.

HY-135639

Alkyne-probe 1	Fluorescent Dye	Others
Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135970

**Alkyne-PEG4-SS-PEG4-alkyne**	ADC Linker	Cancer
Alkyne-PEG4-SS-PEG4-alkyne is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Alkyne-PEG4-SS-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140032

Alkyne-ethyl-PEG1-Boc Alkyne-ethyl-PEG1-t-butyl ester	PROTAC Linkers	Cancer
Alkyne-ethyl-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-ethyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W800840

Alkyne sphinganine	Biochemical Assay Reagents	Others
Alkyne Sphinganine a metabolic labeling reagent that contains a terminal alkyne moiety that allows for the subsequent tagging of protein?lipid complexes by click chemistry. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry’, in the presence of a copper (Cu)-containing catalyst allowing for the visualization and proteomic profiling of protein?sphingolipid complexes in living cells.

HY-133399

Alkyne-PEG4-maleimide	PROTAC Linkers	Cancer
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P10758

Alkyne-βAG-TOCA	Somatostatin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Alkyne-βAG-TOCA, an octreotide derivative, targets somatostatin receptor type 2 (SST2) . Alkyne-βAG-TOCA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-162946

Alkyne-P60	Ligands for Target Protein for PROTAC	Cancer
Alkyne-P60 is a potent 15-mer peptide inhibitor of Foxp3. Alkyne-P60 can bind with Foxp3, hinder its nuclear translocation, and diminish Foxp3-mediated inhibition of NFKB and NFAT functions. Alkyne-P60 is a ligand for target protein for PROTAC (HY-162943).

HY-174969C

Alkyne-PEG-Silane (MW 5000)	Biochemical Assay Reagents	Others
Alkyne-PEG-Silane (MW 5000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 5000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 5000) to modify surfaces such as glass and silicon .

HY-174969A

Alkyne-PEG-Silane (MW 2000)	Biochemical Assay Reagents	Others
Alkyne-PEG-Silane (MW 2000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 2000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 2000) to modify surfaces such as glass and silicon .

HY-174969B

Alkyne-PEG-Silane (MW 3400)	Biochemical Assay Reagents	Others
Alkyne-PEG-Silane (MW 3400) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 3400) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 3400) to modify surfaces such as glass and silicon .

HY-174969

Alkyne-PEG-Silane (MW 1000)	Biochemical Assay Reagents	Others
Alkyne-PEG-Silane (MW 1000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 1000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 1000) to modify surfaces such as glass and silicon .

HY-113803

4-Hydroxynonenal alkyne 4-HNE Alkyne	Biochemical Assay Reagents	Cancer
4-Hydroxynonenal alkyne (4-HNE alkyne) is a click chemical reagent containing alkynes. 4-Hydroxynonenal alkyne induces heme oxygenase and cell apoptosis in colon cancer (RKO) cells .

HY-137073

*Cy7 alkyne* chloride**	Fluorescent Dye	Others
Cy7 alkyne chloride is a dye derivative of Cyanine 7 (Cy7) containing an alkyne functional group (Ex/Em = 740/770 nm). The alkyne functionality of Cy7 alkyne chloride can react with molecules containing the azide functionality to form covalent bonds .

HY-145472

Sphingosine (d18:1) alkyne	Biochemical Assay Reagents	Cancer
Sphingosine (d18:1) alkyne (compound 2b) is an alkyne-labeled Sphingosine (d18:1) that can be used in click chemistry reactions .

HY-176161

13-OxoODE alkyne 13-Keto-9(Z),11(E)-ODE Alkyne; 13-KODE Alkyne	Biochemical Assay Reagents	Others
13-OxoODE alkyne (13-Keto-9(Z),11(E)-ODE alkyne) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1588

BODIPY-X-Alkyne	Fluorescent Dye	Others
BODIPY-X-Alkyne is an alkyne-modified BODIPY derivative (Ex=526 nm, Em=540 nm). BODIPY-X-Alkyne can react with azides via a copper-catalyzed click reaction .

HY-151643

beta-Glc-TEG-Alkyne	ADC Linker	Others
beta-Glc-TEG-Alkyne is a click chemistry reagent containing an *alkynes* group. beta-Glc-TEG-Alkyne can be used for the research of various biochemical .

HY-151649

Biotin-PEG(4)-SS-Alkyne	ADC Linker	Others
Biotin-PEG(4)-SS-Alkyne is a click chemistry reagent containing an *alkyne* group. Biotin-PEG(4)-SS-Alkyne can be used for the research of various biochemical .

HY-151751

BDP TMR alkyne	Fluorescent Dye	Others
BDP TMR alkyne is an alkyne-containing click chemistry reagent that can click chemistry with azides. BDP TMR alkyne has the fluorophore BDP and can be used for oligonucleotide labeling and amino acid sequencing .

HY-D1348

BDP R6G alkyne	Fluorescent Dye	Others
BDP R6G alkyne is an alkyne modified BDP R6G. BDP R6G is a bright and photostable dye (BDP R6G: Ex=530 nm, Em=545 nm). BDP R6G alkyne can be used for labeling using Click chemistry.

HY-151728

Trisulfo-Cy3-Alkyne	Fluorescent Dye	Others
Trisulfo-Cy3-Alkyne is a water soluble cyanine linker containing an alkyne group, which enables Click Chemistry to attach trisulfo-Cy3 to various azide-bearing molecules. Trisulfo-Cyanine3 is a fluorophore which is compatible with a wide range of fluorescent scanners, imagers, microscopes, etc. It is a bright and photostable dye and can be easily detected in gels by naked eye in low amounts (nmol). Reagent grade, for research use only . Trisulfo-Cy3-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1664

BDP 558/568 alkyne	Fluorescent Dye	Others
BDP 558/568 alkyne is a borondipyrromethene dye. BDP 558/568 alkyne possesses high quantum yield. BDP 558/568 alkyne is a terminal alkyne for copper-catalyzed Click chemistry. (λ_ex=558 nm, λ_em=568 nm) .

HY-151680

*TAMRA alkyne, 6-isomer*	DNA Stain	Others
TAMRA alkyne, 6-isomer is a linker of TAMRA which is a xanthene dye with orange emission that is commonly used for oligonucleotide labeling and amino acid sequencing. The addition of the alkyne groups allows for it to be reacted with an azide for copper-catalyzed Click Chemistry .

HY-W440998

DSPE-alkyne	Liposome	Others
DSPE-alkyne is a phospholipid . DSPE-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-138749

Biotin alkyne	PROTAC Linkers	Cancer
Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-120317

CPTH2-Alkyne	Histone Acetyltransferase	Others
CPTH2-Alkyne is a cell active analog of CPTH2 (HY-W013274). CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy .

HY-114354

BODIPY FL alkyne BOD FL Alkyne	Fluorescent Dye	Others
BODIPY FL alkyne (BOD FL alkyne) is a green-fluorescent dye (Ex=503 nm; Em=512 nm), a bright and photostable fluorophore which emits in fluorescein (FAM) channel. BODIPY FL alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.

HY-170757A

*Spermidine-alkyne* trihydrochloride**	Biochemical Assay Reagents	Others
Spermidine-alkyne trihydrochloride is a Spermidine (HY-B1776) derivative endowed with an alkyne handle. Spermidine-alkyne trihydrochloride is a Spermidine probe, which can be used for the determination of the Spermidine binding to cellular proteins .

HY-170757

Spermidine-alkyne	Biochemical Assay Reagents	Others
Spermidine-alkyne is a Spermidine (HY-B1776) derivative endowed with an alkyne handle. Spermidine-alkyne is a Spermidine probe, which can be used for the determination of the Spermidine binding to cellular proteins .

HY-163212

PreQ1-alkyne	Biochemical Assay Reagents	Others
PreQ1-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-155639

Tyramide alkyne 1 Publications Verification	Biochemical Assay Reagents	Others
Tyramide alkyne is an alternative labeling substrate that can be coupled to detection or enrichment moieties via a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) “click” reaction. Tyramide alkyne can be used for ascorbate peroxidase 2 (APEX2) labeling .

HY-W190984A

Desthiobiotin-PEG1-alkyne	Biochemical Assay Reagents	Others
Desthiobiotin-PEG1-alkyne is a PEG derivative composed of desthiobiotin, 1 PEG unit and alkyne. Desthiobiotin-PEG1-alkyne is a click chemistry reagent. It contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an azide group.

HY-115715A

EN219-alkyne	Fluorescent Dye	Cancer
EN219-alkyne is an alkyne-functionalized EN219 probe. EN219 (HY-P0287A) is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC₅₀ of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination . EN219-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151757

Trisulfo-Cy5-Alkyne	Fluorescent Dye	Others
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .

HY-D2114

TAMRA-PEG8-Alkyne	Fluorescent Dye	Others
TAMRA-PEG8-Alkyne is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2113

TAMRA-PEG3-Alkyne	Fluorescent Dye	Others
TAMRA-PEG3-Alkyne is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-120666

TAMRA-PEG4-Alkyne	Fluorescent Dye	Others
TAMRA-PEG4-Alkyne is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-161390

SPC-alkyne	Interleukin Related	Inflammation/Immunology Cancer
SPC-alkyne (compound 9) is an alkynyl derivative. SPC-alkyne suppresses IL-2 production and AP-1 and NFAT reporters .

HY-133496

Folate-PEG3-alkyne	PROTAC Linkers	Cancer
Folate-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Folate-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130913

5-FAM-Alkyne	Phosphatase	Others
5-FAM-Alkyne is a high selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP) . 5-FAM-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140922

Biotin-PEG4-alkyne 1 Publications Verification	PROTAC Linkers	Cancer
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-136046

PTAD-PEG4-alkyne	ADC Linker	Cancer
PTAD-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PTAD-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name

HY-L908

Lead-like Covalent Screening Library

1,262 compounds

Small molecule covalent inhibitors, or irreversible inhibitors, are a type of inhibitors that exert their biological functions by irreversibly binding to target through covalent bonds. Compared with non-covalent inhibitors, covalent inhibitors have obvious advantages in bioactivity, such that covalent warheads can target rare residues of a particular target protein, thus leading to the development of highly selective inhibitors and achieving a more complete and continued target occupancy in living systems. In recent years, the distinct strengths of covalent inhibitors in overcoming drug resistance had been recognized. However, toxicity can be a real challenge related to this class of therapeutics due to their potential for off-target reactivity and has led to these drugs being disfavored as a drug class. The drug design and optimization of covalent inhibitors has become a hot spot in drug discovery.

MCE Lead-like Covalent Screening Library offers a valuable resource of 1,049 lead-like compounds with commonly used covalent warheads. These warheads, such as acrylamide, activated terminal alkyne, acyloxymethyl ketone, and boronic acid, are capable of reacting with specific amino acid residues, including cysteine, lysine, serine, and histidine. The inclusion of these reactive warheads in the library allows researchers to explore the potential of covalent inhibition, a powerful approach in drug discovery.

Cat. No.	Product Name	Type

HY-137042

Cyanine5 alkyne

Alkyne-Cy5

Fluorescent Dyes/Probes

Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1588

BODIPY-X-Alkyne	Fluorescent Dyes/Probes
BODIPY-X-Alkyne is an alkyne-modified BODIPY derivative (Ex=526 nm, Em=540 nm). BODIPY-X-Alkyne can react with azides via a copper-catalyzed click reaction .

HY-151751

BDP TMR alkyne	Fluorescent Dyes/Probes
BDP TMR alkyne is an alkyne-containing click chemistry reagent that can click chemistry with azides. BDP TMR alkyne has the fluorophore BDP and can be used for oligonucleotide labeling and amino acid sequencing .

HY-120317

CPTH2-Alkyne	Fluorescent Dyes/Probes
CPTH2-Alkyne is a cell active analog of CPTH2 (HY-W013274). CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy .

HY-114354

BODIPY FL alkyne BOD FL Alkyne	Fluorescent Dyes/Probes
BODIPY FL alkyne (BOD FL alkyne) is a green-fluorescent dye (Ex=503 nm; Em=512 nm), a bright and photostable fluorophore which emits in fluorescein (FAM) channel. BODIPY FL alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.

HY-135639

Alkyne-probe 1	Fluorescent Dyes/Probes
Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-137073

*Cy7 alkyne* chloride**	Fluorescent Dyes/Probes
Cy7 alkyne chloride is a dye derivative of Cyanine 7 (Cy7) containing an alkyne functional group (Ex/Em = 740/770 nm). The alkyne functionality of Cy7 alkyne chloride can react with molecules containing the azide functionality to form covalent bonds .

HY-D1348

BDP R6G alkyne	Fluorescent Dyes/Probes
BDP R6G alkyne is an alkyne modified BDP R6G. BDP R6G is a bright and photostable dye (BDP R6G: Ex=530 nm, Em=545 nm). BDP R6G alkyne can be used for labeling using Click chemistry.

HY-D1664

BDP 558/568 alkyne	Fluorescent Dyes/Probes
BDP 558/568 alkyne is a borondipyrromethene dye. BDP 558/568 alkyne possesses high quantum yield. BDP 558/568 alkyne is a terminal alkyne for copper-catalyzed Click chemistry. (λ_ex=558 nm, λ_em=568 nm) .

HY-151757

Trisulfo-Cy5-Alkyne	Fluorescent Dyes/Probes
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .

HY-D2114

TAMRA-PEG8-Alkyne	Fluorescent Dyes/Probes
TAMRA-PEG8-Alkyne is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2113

TAMRA-PEG3-Alkyne	Fluorescent Dyes/Probes
TAMRA-PEG3-Alkyne is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1593

BODIPY TMR-X alkyne	Fluorescent Dyes/Probes
BODIPY TMR-X alkyne, an orange-fluorescent dye, is an alkyne modified BODIPY TMR-X. BODIPY TMR-X alkyne can react with azides by the copper-catalyzed click reaction. BODIPY TMR-X alkyne is not sensitive to pH.

HY-D1860

Cy3 alkyne chloride

Fluorescent Dyes/Probes

Cy3 alkyne chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing a sulfonate ion and an alkyne functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy3 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

HY-D2230

Cy3.5 alkyne	Fluorescent Dyes/Probes
Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .

HY-151753

Trisulfo-Cy5.5-Alkyne	Fluorescent Dyes/Probes
Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.

HY-D1924

ATTO 390 alkyne	Fluorescent Dyes/Probes
ATTO 390 alkyne is an alkyne derivative of ATTO 390 with maximum excitation/emission wavelengths: 390/476 nm. ATTO 390 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2139

Cy3-PEG3-Alkyne	Fluorescent Dyes/Probes
Cy3-PEG3-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2141

Cy3-PEG8-Alkyne	Fluorescent Dyes/Probes
Cy3-PEG8-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 8 PEG units. Cy3-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2140

Cy3-PEG4-Alkyne	Fluorescent Dyes/Probes
Cy3-PEG4-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 4 PEG units. Cy3-PEG4-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151704

ICG-alkyne	Fluorescent Dyes/Probes
ICG-alkyne is a click chemistry reagent containing an azide group .

HY-163140

BODIPY-phenyl-amide-alkyne	Fluorescent Dyes/Probes
BODIPY-phenyl-amide-alkyne (compound 6) is an alkyne-containing OFF-to-ON fluorophore. BODIPY-phenyl-amide-alkyne is a BODIPY derivative that can be conjugated to protein IL-33 Y143azidoPhe via CuAAC reaction .

HY-151756

diSulfo-Cy3 alkyne	Fluorescent Dyes/Probes
diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an alkyne group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase .

HY-D1862

Cy7.5 alkyne chloride

Fluorescent Dyes/Probes

Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

Cat. No.	Product Name	Type

HY-151705

Alkyne Cholesterol 1 Publications Verification	Drug Delivery
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-W074785

Carboxyl diazirine alkyne	Biochemical Assay Reagents
Carboxyl diazirine alkyne is a protein cross-linking compound. Carboxyl diazirine alkyne play crucial roles in the research on the inhibition and labeling of FTO protein by fluorescein derivatives .

HY-174969C

Alkyne-PEG-Silane (MW 5000)

Drug Delivery

Alkyne-PEG-Silane (MW 5000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 5000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 5000) to modify surfaces such as glass and silicon .

HY-174969A

Alkyne-PEG-Silane (MW 2000)

Drug Delivery

Alkyne-PEG-Silane (MW 2000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 2000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 2000) to modify surfaces such as glass and silicon .

HY-174969B

Alkyne-PEG-Silane (MW 3400)

Drug Delivery

Alkyne-PEG-Silane (MW 3400) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 3400) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 3400) to modify surfaces such as glass and silicon .

HY-174969

Alkyne-PEG-Silane (MW 1000)

Drug Delivery

Alkyne-PEG-Silane (MW 1000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 1000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 1000) to modify surfaces such as glass and silicon .

HY-W440998

DSPE-alkyne	Drug Delivery
DSPE-alkyne is a phospholipid . DSPE-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W190984A

Desthiobiotin-PEG1-alkyne	Drug Delivery
Desthiobiotin-PEG1-alkyne is a PEG derivative composed of desthiobiotin, 1 PEG unit and alkyne. Desthiobiotin-PEG1-alkyne is a click chemistry reagent. It contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an azide group.

HY-W190984

Desthiobiotin-PEG4-alkyne	Biochemical Assay Reagents
Desthiobiotin-PEG4-alkyne is a biotinylated biochemical reagent, which can be utilized in conjunction with click chemistry for the selective labeling and enrichment of certain tRNAs .

Cat. No.	Product Name	Target	Research Area

HY-P6438

Alkyne-cRGD	Integrin	Others Cancer
Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD undergoes copper-catalyzed azide-alkyne cycloaddition reaction .

HY-P10758

Alkyne-βAG-TOCA	Somatostatin Receptor	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Alkyne-βAG-TOCA, an octreotide derivative, targets somatostatin receptor type 2 (SST2) . Alkyne-βAG-TOCA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-162946

Alkyne-P60	Ligands for Target Protein for PROTAC	Cancer
Alkyne-P60 is a potent 15-mer peptide inhibitor of Foxp3. Alkyne-P60 can bind with Foxp3, hinder its nuclear translocation, and diminish Foxp3-mediated inhibition of NFKB and NFAT functions. Alkyne-P60 is a ligand for target protein for PROTAC (HY-162943).

Cat. No.	Product Name		Classification

HY-151646

Alkyne-PEG5-SNAP Alkyne-PEG5-BG		Labeling and Fluorescence Imaging Alkynes
Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151645

Alkyne-SNAP		Alkynes Labeling and Fluorescence Imaging
Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .

HY-151705

Alkyne Cholesterol 1 Publications Verification		Alkynes Labeling and Fluorescence Imaging
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-137042

Cyanine5 alkyne Alkyne-Cy5		Alkynes Labeling and Fluorescence Imaging
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P6438

Alkyne-cRGD		Alkynes
Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD undergoes copper-catalyzed azide-alkyne cycloaddition reaction .

HY-131442

Alkyne-phenol 2 Publications Verification Alkyne tyramide; Alk-Ph		Labeling and Fluorescence Imaging Alkynes
Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins . Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151790

Alkyne-SS-COOH		Alkynes
Alkyne-SS-COOH is a click chemistry reagent containing an *alkyne* group. Alkyne-SS-COOH can be used for the research of various biochemical .

HY-151665

Alkyne-PEG2-iodide		Alkynes
Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.

HY-135639

Alkyne-probe 1		Labeling and Fluorescence Imaging Alkynes
Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135970

**Alkyne-PEG4-SS-PEG4-alkyne**		ADC Synthesis Alkynes
Alkyne-PEG4-SS-PEG4-alkyne is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Alkyne-PEG4-SS-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140032

Alkyne-ethyl-PEG1-Boc Alkyne-ethyl-PEG1-t-butyl ester		PROTAC Synthesis Alkynes
Alkyne-ethyl-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-ethyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-133399

Alkyne-PEG4-maleimide		PROTAC Synthesis Alkynes
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P10758

Alkyne-βAG-TOCA		Alkynes
Alkyne-βAG-TOCA, an octreotide derivative, targets somatostatin receptor type 2 (SST2) . Alkyne-βAG-TOCA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-162946

Alkyne-P60		Alkynes
Alkyne-P60 is a potent 15-mer peptide inhibitor of Foxp3. Alkyne-P60 can bind with Foxp3, hinder its nuclear translocation, and diminish Foxp3-mediated inhibition of NFKB and NFAT functions. Alkyne-P60 is a ligand for target protein for PROTAC (HY-162943).

HY-113803

4-Hydroxynonenal alkyne 4-HNE Alkyne		Alkynes
4-Hydroxynonenal alkyne (4-HNE alkyne) is a click chemical reagent containing alkynes. 4-Hydroxynonenal alkyne induces heme oxygenase and cell apoptosis in colon cancer (RKO) cells .

HY-145472

Sphingosine (d18:1) alkyne		Alkynes
Sphingosine (d18:1) alkyne (compound 2b) is an alkyne-labeled Sphingosine (d18:1) that can be used in click chemistry reactions .

HY-151643

beta-Glc-TEG-Alkyne		Alkynes
beta-Glc-TEG-Alkyne is a click chemistry reagent containing an *alkynes* group. beta-Glc-TEG-Alkyne can be used for the research of various biochemical .

HY-151649

Biotin-PEG(4)-SS-Alkyne		Alkynes
Biotin-PEG(4)-SS-Alkyne is a click chemistry reagent containing an *alkyne* group. Biotin-PEG(4)-SS-Alkyne can be used for the research of various biochemical .

HY-151751

BDP TMR alkyne		Labeling and Fluorescence Imaging
BDP TMR alkyne is an alkyne-containing click chemistry reagent that can click chemistry with azides. BDP TMR alkyne has the fluorophore BDP and can be used for oligonucleotide labeling and amino acid sequencing .

HY-151728

Trisulfo-Cy3-Alkyne		Labeling and Fluorescence Imaging Alkynes
Trisulfo-Cy3-Alkyne is a water soluble cyanine linker containing an alkyne group, which enables Click Chemistry to attach trisulfo-Cy3 to various azide-bearing molecules. Trisulfo-Cyanine3 is a fluorophore which is compatible with a wide range of fluorescent scanners, imagers, microscopes, etc. It is a bright and photostable dye and can be easily detected in gels by naked eye in low amounts (nmol). Reagent grade, for research use only . Trisulfo-Cy3-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151680

*TAMRA alkyne, 6-isomer*		Alkynes Labeling and Fluorescence Imaging
TAMRA alkyne, 6-isomer is a linker of TAMRA which is a xanthene dye with orange emission that is commonly used for oligonucleotide labeling and amino acid sequencing. The addition of the alkyne groups allows for it to be reacted with an azide for copper-catalyzed Click Chemistry .

HY-145469

Linoleic acid alkyne		Alkynes
Linoleic acid alkyne is an ω-alkyne derivative of Linoleic acid (HY-N0729). Linoleic acid alkyne can be used to synthesize other alkyne-containing products,such as glycerophospholipids, for click chemistry .

HY-138749

Biotin alkyne		PROTAC Synthesis Alkynes
Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-120317

CPTH2-Alkyne		Alkynes
CPTH2-Alkyne is a cell active analog of CPTH2 (HY-W013274). CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy .

HY-158594

Docosahexaenoic acid alkyne DHA-Alkyne; FA 22:8		Alkynes
Docosahexaenoic acid alkyne (FA 22:8) is the ω-alkyne derivative of Docosahexaenoic acid (HY-B2167) .

HY-170757

Spermidine-alkyne		Alkynes
Spermidine-alkyne is a Spermidine (HY-B1776) derivative endowed with an alkyne handle. Spermidine-alkyne is a Spermidine probe, which can be used for the determination of the Spermidine binding to cellular proteins .

HY-163212

PreQ1-alkyne		Alkynes
PreQ1-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-115715A

EN219-alkyne		Alkynes
EN219-alkyne is an alkyne-functionalized EN219 probe. EN219 (HY-P0287A) is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC₅₀ of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination . EN219-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151757

Trisulfo-Cy5-Alkyne		Alkynes Labeling and Fluorescence Imaging
Trisulfo-Cy5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5-Alkyne is a near infrared (NIR) fluorescent dye .

HY-D2114

TAMRA-PEG8-Alkyne		Labeling and Fluorescence Imaging Alkynes
TAMRA-PEG8-Alkyne is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2113

TAMRA-PEG3-Alkyne		Labeling and Fluorescence Imaging Alkynes
TAMRA-PEG3-Alkyne is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-120666

TAMRA-PEG4-Alkyne		PROTAC Synthesis Alkynes
TAMRA-PEG4-Alkyne is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-161390

SPC-alkyne		Alkynes
SPC-alkyne (compound 9) is an alkynyl derivative. SPC-alkyne suppresses IL-2 production and AP-1 and NFAT reporters .

HY-133496

Folate-PEG3-alkyne		PROTAC Synthesis Alkynes
Folate-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Folate-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130913

5-FAM-Alkyne		Labeling and Fluorescence Imaging Alkynes
5-FAM-Alkyne is a high selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP) . 5-FAM-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140922

Biotin-PEG4-alkyne 1 Publications Verification		Alkynes PROTAC Synthesis
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-136046

PTAD-PEG4-alkyne		Alkynes ADC Synthesis
PTAD-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PTAD-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-136075

HyNic-PEG4-alkyne		Alkynes ADC Synthesis
HyNic-PEG4-alkyne is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . HyNic-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-136101

Bocaminooxyacetamide-PEG3-alkyne		ADC Synthesis Alkynes
Bocaminooxyacetamide-PEG3-alkyne is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Bocaminooxyacetamide-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-133870

Itaconate-alkyne 2 Publications Verification ITalk		Alkynes
Itaconate-alkyne (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. Itaconate-alkyne, a functional analogue of Itaconate, exhibits comparable antiinflammatory effect with Itaconate and enables the labeling of bona fide targets of Itaconate . Itaconate-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-128522

ARS-1323-alkyne		Alkynes
ARS-1323-alkyne is a covalent inhibitor probe that covalently binds to the Switch-II pocket (S-IIP) of the KRAS G12C mutant protein. ARS-1323-alkyne visualizes the covalent modification of KRAS G12C and quantitatively measures the binding efficiency of the inhibitor to the target. ARS-1323-alkyne can be used to validate the target occupancy of KRAS G12C inhibitors and the synergistic mechanism of combination therapy, providing tool support for the development of combination treatment strategies .

HY-133430

DBCO-PEG4-alkyne		DBCO Alkynes ADC Synthesis
DBCO-PEG4-alkyne is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-137018

*27-Alkyne* cholesterol**		Alkynes
27-Alkyne cholesterol is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as click chemistry, in the presence of a copper-containing catalyst. Alkyne cholesterol represents a versatile, sensitive, and easy-to-use tool for tracking cellular cholesterol metabolism and localization as it allows for manifold detection methods including mass spectrometry, and fluorescence microscopy.

HY-136205

IA-Alkyne Iodoacetamide-Alkyne; N-Hex-5-ynyl-2-iodo-acetamide		Alkynes
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-133437

BCN-PEG4-alkyne		PROTAC Synthesis Alkynes BCN
BCN-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-alkyne is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D1593

BODIPY TMR-X alkyne		Labeling and Fluorescence Imaging Alkynes
BODIPY TMR-X alkyne, an orange-fluorescent dye, is an alkyne modified BODIPY TMR-X. BODIPY TMR-X alkyne can react with azides by the copper-catalyzed click reaction. BODIPY TMR-X alkyne is not sensitive to pH.

HY-D1860

*Cy3 alkyne* chloride**		Alkynes
Cy3 alkyne chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing a sulfonate ion and an alkyne functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy3 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

HY-D2230

Cy3.5 alkyne		Alkynes
Cy3.5 alkyne, a fluorescent dye, is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Cy3.5 alkyne can be used for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition .

HY-W423080

*TAMRA alkyne,5-isomer*		Alkynes
TAMRA alkyne, 5-isomer (Compound 3) is an alkyne derivative of TAMRA and can be used for the enrichment, in-gel fluorescence detection, and identification of O-GlcNAc-modified proteins. TAMRA alkyne, 5-isomer contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Azide groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .

HY-W615166

Thalidomide-NH-C2-alkyne		Alkynes
Thalidomide-NH-C2-alkyne contains an E3 ligase ligand with an alkyl linker, and a terminal alkyne. Thalidomide-NH-C2-alkyne is ready for conjugation to target proteins for PROTAC R&D.

Cat. No.	Product Name		Classification

HY-151705

Alkyne Cholesterol 1 Publications Verification		Cholesterol
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an *alkyne* group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization .

HY-W440998

DSPE-alkyne		Phospholipids
DSPE-alkyne is a phospholipid . DSPE-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

16:0(Alkyne)-18:1 PE

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Click Chemistry

Oligonucleotides

Natural
Products