Search Result
Results for "
14:0-14:0(COOH) PC
" in MedChemExpress (MCE) Product Catalog:
11
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P1170
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Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
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Opioid Receptor
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Neurological Disease
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N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
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-
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- HY-157080
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DBM-C5-COOH
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ADC Linker
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Cancer
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Dibromomaleimide-C5-COOH (DBM-C5-COOH) is a bifunctional dibromomaleimide (DBM) linker. Dibromomaleimide-C5-COOH can be used to connect MMAF and to synthesize ADC .
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- HY-W096106
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PROTAC Linkers
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Cancer
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CH2COOH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-122696
-
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PROTAC Linkers
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Cancer
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CH2COOH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-163758
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PROTAC Linkers
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Cancer
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COOH-C3-COGN-C7-COOH is a PEG based linker for PROTAC. COOH-C3-COGN-C7-COOH can be used for synthesis of PROTAC Degrader ARM165 (HY-163677) .
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-
-
- HY-169236
-
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PROTAC Linkers
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Cancer
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COOH-C-PEG2-NHCO-C2-COOH is a PROTAC linker that is used to synthesize PCC16 chloride (HY-169232) .
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-
-
- HY-P10973
-
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CXCR
ERK
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Cancer
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Peptide R analogue 10 (compound 10) is an analog of the CXCR4 antagonist peptide Peptide R (HY-P4111) with stronger antagonistic potency, specificity and plasma stability. Peptide R analogue 10 can inhibit CXCL12-mediated cell migration, ERK phosphorylation and CXCR4 internalization. Peptide R analogue 10 can be used in the study of CXCR4 overexpressing leukemia and colon cancer .
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- HY-P11011
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Pep R54; CXCR4 antagonist peptide 19
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CXCR
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Cancer
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Peptide R54 (Pep R54; CXCR4 antagonist peptide 19) is an antagonistic peptide targeting CXCR4 with significant anticancer activity. Peptide R54 inhibits CXCR4-dependent cell migration, epithelial-mesenchymal transition, and lung metastasis development, with better serum stability and higher CXCR4 affinity than the lead compound (IC50=20 nM). Peptide R54 synergizes with anti-PD-1 therapy to exert anti-tumor activity in vivo, enhances granzyme activity, and reduces infiltration of Foxp3 cells. Peptide R54 can be used in the study of colon cancer, ovarian cancer, and melanoma .
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-
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- HY-N15997
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-
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- HY-132113
-
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PROTAC Linkers
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Cancer
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CH2COOH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
-
- HY-138514
-
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PROTAC Linkers
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Cancer
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CH2COOH-PEG9-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
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- HY-139539
-
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Ligands for E3 Ligase
Autophagy
Apoptosis
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Cancer
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Thalidomide-5-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-COOH can be connected to the ligand for protein by a linker to form PROTACs .
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-
-
- HY-P10964
-
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GHSR
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Endocrinology
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Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research of diseases such as acromegaly caused by excessive growth hormone secretion .
|
-
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- HY-150352
-
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Biochemical Assay Reagents
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Others
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Dextran-COOH is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and other functional materials .
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- HY-156388
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PROTAC Linkers
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Cancer
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SCO-PEG8-COOH is a PROTAC linker and belongs to the PEG class. SCO-PEG8-COOH contains SCO and COOH that can be covalently combined with amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-156387
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PROTAC Linkers
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Cancer
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SCO-PEG4-COOH is a PROTAC linker and belongs to the PEG class. SCO-PEG4-COOH contains SCO and COOH that can be covalently combined with amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-156386
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PROTAC Linkers
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Cancer
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SCO-PEG3-COOH is a PROTAC linker and belongs to the PEG class. SCO-PEG3-COOH contains SCO and COOH that can be covalently combined with amino groups respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-133799
-
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders .
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-
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- HY-145013
-
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LYTACs
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Others
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tri-GalNAc-COOH acetylation is the acetylated and modified form of tri-GalNAc-COOH. tri-GalNAc-COOH acetylation can be used for the synthesis of LYTAC.
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-
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- HY-149750
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-
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- HY-W045598
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ADC Linker
PROTAC Linkers
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Cancer
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Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C16-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs
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-
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- HY-D2110
-
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Fluorescent Dye
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Others
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TAMRA-PEG8-COOH is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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- HY-W034599
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ADC Linker
PROTAC Linkers
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Cancer
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Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-C14-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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- HY-D2109
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Fluorescent Dye
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Others
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TAMRA-PEG4-COOH is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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- HY-D2108
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Fluorescent Dye
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Others
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TAMRA-PEG3-COOH is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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-
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- HY-D2881
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Rhodamine B-PEG-COOH (MW 400)
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Fluorescent Dye
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Others
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RB-PEG-COOH (MW 400) (Rhodamine B-PEG-COOH (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 400) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
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- HY-D2881C
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Rhodamine B-PEG-COOH (MW 2000)
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Fluorescent Dye
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Others
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RB-PEG-COOH (MW 2000) (Rhodamine B-PEG-COOH (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 2000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
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- HY-D2881D
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Rhodamine B-PEG-COOH (MW 3400)
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Fluorescent Dye
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Others
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RB-PEG-COOH (MW 3400) (Rhodamine B-PEG-COOH (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 3400) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
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-
-
- HY-D2881H
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Rhodamine B-PEG-COOH (MW 10000)
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Fluorescent Dye
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Others
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RB-PEG-COOH (MW 10000) (Rhodamine B-PEG-COOH (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 10000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
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- HY-D2881B
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Rhodamine B-PEG-COOH (MW 1000)
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Fluorescent Dye
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Others
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RB-PEG-COOH (MW 1000) (Rhodamine B-PEG-COOH (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 1000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
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- HY-D2881A
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Rhodamine B-PEG-COOH (MW 600)
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Fluorescent Dye
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Others
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RB-PEG-COOH (MW 600) (Rhodamine B-PEG-COOH (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 600) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
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- HY-D2881E
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Rhodamine B-PEG-COOH (MW 5000)
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Fluorescent Dye
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Others
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RB-PEG-COOH (MW 5000) (Rhodamine B-PEG-COOH (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 5000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
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- HY-149751
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Biochemical Assay Reagents
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Others
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Methylthiomcresol-C5-COOH (Compound F4) is a hapten that can be conjugated to carrier proteins for antigen design. Methylthiomcresol-C5-COOH designed antigen can be applied in ELISA to detect the residual amount of fenthion in white wine samples .
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- HY-149749
-
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Biochemical Assay Reagents
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Others
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Methylthiomcresol-C3-COOH (Compound F2) is a hapten that can be conjugated to carrier proteins for antigen design. Methylthiomcresol-C3-COOH designed antigen can be applied in ELISA to detect the residual amount of fenthion in white wine samples .
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- HY-168662
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Ligands for Target Protein for PROTAC
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Cancer
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Palbociclib-CH2COOH is a Ligands for Target Protein for PROTACs. Palbociclib-CH2COOH can serve as an active control for the target protein ligand of CPD-39 (HY-168664) and CPD-10 (HY-168660) .
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- HY-P5568
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RP 71955
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HIV
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Infection
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RP 71955 is an antimicrobial peptide against HIV-1 .
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- HY-D1883
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Fluorescent Dye
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Others
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Cy7.5-COOH (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
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- HY-133699
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide-PEG4-COOH is a E3 ligase ligand-linker conjugate. Pomalidomide-PEG4-COOH contains the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology (extracted from patent WO2017184995A1) .
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- HY-135045
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VH032-C4-COOH
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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(S,R,S)-AHPC-C4-COOH (VH032-C4-COOH) (linker 45) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-targeted PROTAC .
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- HY-151790
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ADC Linker
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Others
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Alkyne-SS-COOH is a click chemistry reagent containing an alkyne group. Alkyne-SS-COOH can be used for the research of various biochemical .
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- HY-130952
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-
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- HY-49223
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-
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- HY-W835383
-
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Fluorescent Dye
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Others
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Sulfo-Cy5.5-COOH is a sulfonated Cy5.5 fluorescent dye containing a sulfonic acid group and a carboxylic acid group. The fluorescence wavelength of Sulfo-Cy5.5-COOH is in the near-infrared region and has strong penetrating power.
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- HY-134700
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PROTAC Linkers
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Cancer
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DSPE-PEG14-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138498
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PROTAC Linkers
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Cancer
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F-PEG2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130348
-
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PROTAC Linkers
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Cancer
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OPSS-PEG8-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138314
-
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PROTAC Linkers
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Cancer
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m-PEG16-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141799
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Ligands for Target Protein for PROTAC
WDR5
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Cancer
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Dimethyl-F-OICR-9429-COOH a ligand for WD40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1 intermediate 19. Dimethyl-F-OICR-9429-COOH can be used in the synthesis of PROTACs .
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- HY-157262
-
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Others
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Infection
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Methyl isonicotinate-(CH2)2-COOH (hapten 2b) is a hapten that can be activated with NHS and DCC. Methyl isonicotinate-(CH2)2-COOH has more immunogenicity and hydrophobicity .
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- HY-131717
-
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Ligands for E3 Ligase
Autophagy
Apoptosis
|
Cancer
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Thalidomide-NH-CH2-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937) .
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- HY-D1883B
-
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Fluorescent Dye
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Others
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Cy7.5-COOH bromide, a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH bromide can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
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- HY-141593
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- HY-156494
-
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ADC Linker
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Cancer
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Me-Tet-PEG9-COOH is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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- HY-156475
-
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ADC Linker
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Cancer
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Me-Tet-PEG2-COOH is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-COOH can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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- HY-156492
-
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ADC Linker
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Cancer
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Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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- HY-156493
-
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ADC Linker
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Cancer
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Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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- HY-W026082
-
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Biochemical Assay Reagents
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Inflammation/Immunology
|
4-Ketobenztriazine-CH2COOH (compound BA) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 4-Ketobenztriazine-CH2COOH can be combined with carrier proteins and used in antigen design .
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- HY-46859
-
-
- HY-D1883A
-
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Fluorescent Dye
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Others
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Cy7.5-COOH TEA (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH TEA can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
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- HY-D2795A
-
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Fluorescent Dye
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Others
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FITC-PEG-COOH (MW 1000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG-COOH (MW 1000) can be used for fluorescent labeling and imaging .
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-
- HY-D2795
-
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Fluorescent Dye
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Others
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FITC-PEG-COOH (MW 400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG-COOH (MW 400) can be used for fluorescent labeling and imaging .
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- HY-D2795C
-
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Fluorescent Dye
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Others
|
FITC-PEG-COOH (MW 10000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG-COOH (MW 10000) can be used for fluorescent labeling and imaging .
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-
- HY-D2795B
-
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Fluorescent Dye
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Others
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FITC-PEG-COOH (MW 5000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG-COOH (MW 5000) can be used for fluorescent labeling and imaging .
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-
- HY-169094
-
-
- HY-136005
-
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E3 Ligase Ligand-Linker Conjugates
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Others
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VH032-C7-COOH is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH032-C7-COOH contains an E3 ligase ligand and an alkyl linker with a terminal amine for conjugation of target protein ligands .
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- HY-W584518
-
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E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.
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- HY-157260
-
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Others
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Infection
|
Propylbenzene-(CH2)2-COOH (2c) is a hapten with high titer and inhibition ratio .
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- HY-W591338B
-
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PROTAC Linkers
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Cancer
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HO-PEG-CH2COOH (MW 35000) is a PROTAC linker belonging to the PEG class. HO-PEG-CH2COOH (MW 35000) can be used to synthesize PROTAC molecule .
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- HY-153959
-
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E3 Ligase Ligand-Linker Conjugates
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Cancer
|
Thalidomide-O-amido-C11-COOH (compound IMiD acid 1) is an E3 ligase ligand and linker CRBN (Cereblon) conjugate. Thalidomide-O-amido-C11-COOH can be used to synthesize PROTAC that target the degradation of DOT1L .
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- HY-145790
-
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Biochemical Assay Reagents
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Cancer
|
Difluorocyclooctyne-CH2-COOH is a Difluorinated cyclooctyne (DIFO) analogue that can be used for imaging glycans on live cells. Difluorinated cyclooctyne (DIFO) reagents rapidly reacts with azides in living cells without the need for copper catalysis . Difluorocyclooctyne-CH2-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W591338A
-
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PROTAC Linkers
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Others
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HO-PEG-CH2COOH (MW 10000) is a PEG polymer with -COOH that can be used as a PROTAC linker to the synthesis of PROTACs .
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- HY-134744
-
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PROTAC Linkers
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Cancer
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Boc-Pyrrolidine-PEG2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138509
-
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PROTAC Linkers
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Cancer
|
NHS ester-PEG13-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138511
-
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PROTAC Linkers
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Cancer
|
NHS ester-PEG7-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-136055
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VH032-C5-COOH
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E3 Ligase Ligand-Linker Conjugates
HIF/HIF Prolyl-Hydroxylase
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Cancer
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(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a Kd of 185 nM, has the potential for the study of anemia and ischemic diseases .
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- HY-131717A
-
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Ligands for E3 Ligase
Autophagy
Apoptosis
|
Cancer
|
Thalidomide-NH-CH2-COOH TFA is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-CH2-COOH TFA can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937) .
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- HY-D1040
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Cyanine 5.5 carboxylic acid
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Fluorescent Dye
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Others
|
Cy5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH can be used for bioimaging and disease diagnosis .
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- HY-D1040A
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Cyanine 5.5 carboxylic acid chloride
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Fluorescent Dye
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Others
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Cy5.5-COOH (Cyanine 5.5 carboxylic acid) chloride is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH chloride possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH chloride can be used for bioimaging and disease diagnosis .
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-
- HY-138778
-
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E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
Thalidomide-Propargyne-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology . Thalidomide-Propargyne-PEG1-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-138776
-
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E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
|
Cancer
|
Thalidomide-Propargyne-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology . Thalidomide-Propargyne-PEG3-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-138777
-
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E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
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Cancer
|
Thalidomide-Propargyne-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology . Thalidomide-Propargyne-PEG2-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-170706
-
|
Liposome
|
Cancer
|
DSPE-PEG(2000)-COOH is a PEGylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530) .
|
-
- HY-120537
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
m-PEG5-CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG5-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-W888710C
-
Folate-PEG-COOH (MW 1000)
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Biochemical Assay Reagents
|
Others
|
FA-PEG-COOH (MW 1000) (Folate-PEG-COOH (MW 1000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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-
- HY-W888710A
-
Folate-PEG-COOH (MW 400)
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Biochemical Assay Reagents
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Others
|
FA-PEG-COOH (MW 400) (Folate-PEG-COOH (MW 400)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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-
- HY-W888710D
-
Folate-PEG-COOH (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
FA-PEG-COOH (MW 2000) (Folate-PEG-COOH (MW 2000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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-
- HY-W888710E
-
Folate-PEG-COOH (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
FA-PEG-COOH (MW 3400) (Folate-PEG-COOH (MW 3400)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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-
- HY-W888710B
-
Folate-PEG-COOH (MW 600)
|
Biochemical Assay Reagents
|
Others
|
FA-PEG-COOH (MW 600) (Folate-PEG-COOH (MW 600)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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-
- HY-W888710H
-
Folate-PEG-COOH (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
FA-PEG-COOH (MW 5000) (Folate-PEG-COOH (MW 5000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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-
- HY-W888710I
-
Folate-PEG-COOH (MW 10000)
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Biochemical Assay Reagents
|
Others
|
FA-PEG-COOH (MW 10000) (Folate-PEG-COOH (MW 10000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
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-
- HY-148484
-
|
Drug Derivative
|
Others
|
Pomalidomide-5'-PEG5-C2-COOH is an active compound. Pomalidomide-5'-PEG5-C2-COOH can be used for the research of various biochemical .
|
-
- HY-138773
-
-
- HY-138775
-
-
- HY-138774
-
-
- HY-153013
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis .
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-
- HY-131184
-
|
PROTAC Linkers
|
Inflammation/Immunology
|
N-Boc-piperazine-C3-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-N-piperazine-C3-COOH can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183) .
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-
- HY-168941A
-
-
- HY-168941
-
-
Cat. No. |
Product Name |
Type |
-
- HY-D2110
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG8-COOH is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2109
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG4-COOH is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2108
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG3-COOH is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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-
- HY-D2881
-
Rhodamine B-PEG-COOH (MW 400)
|
Dyes
|
RB-PEG-COOH (MW 400) (Rhodamine B-PEG-COOH (MW 400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 400) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2881C
-
Rhodamine B-PEG-COOH (MW 2000)
|
Dyes
|
RB-PEG-COOH (MW 2000) (Rhodamine B-PEG-COOH (MW 2000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 2000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2881D
-
Rhodamine B-PEG-COOH (MW 3400)
|
Dyes
|
RB-PEG-COOH (MW 3400) (Rhodamine B-PEG-COOH (MW 3400)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 3400) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2881H
-
Rhodamine B-PEG-COOH (MW 10000)
|
Dyes
|
RB-PEG-COOH (MW 10000) (Rhodamine B-PEG-COOH (MW 10000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 10000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2881B
-
Rhodamine B-PEG-COOH (MW 1000)
|
Dyes
|
RB-PEG-COOH (MW 1000) (Rhodamine B-PEG-COOH (MW 1000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 1000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2881A
-
Rhodamine B-PEG-COOH (MW 600)
|
Dyes
|
RB-PEG-COOH (MW 600) (Rhodamine B-PEG-COOH (MW 600)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 600) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D2881E
-
Rhodamine B-PEG-COOH (MW 5000)
|
Dyes
|
RB-PEG-COOH (MW 5000) (Rhodamine B-PEG-COOH (MW 5000)) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG-COOH (MW 5000) can be used for fluorescent labeling and imaging (Ex/Em = 546/610 nm) .
|
-
- HY-D1883
-
|
Fluorescent Dyes/Probes
|
Cy7.5-COOH (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-D1883B
-
|
Fluorescent Dyes/Probes
|
Cy7.5-COOH bromide, a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH bromide can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-D1883A
-
|
Fluorescent Dyes/Probes
|
Cy7.5-COOH TEA (compound 8f), a cyanine dye, is a highly fluorescent compound (Abs/Em = 781/808 nm). Cy7.5-COOH TEA can be used as a fluorescent probe in a wide-range of applications such as DNA sequencing, flow cytometry and in vivo imaging .
|
-
- HY-D2795A
-
|
Fluorescent Dyes/Probes
|
FITC-PEG-COOH (MW 1000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG-COOH (MW 1000) can be used for fluorescent labeling and imaging .
|
-
- HY-D2795
-
|
Fluorescent Dyes/Probes
|
FITC-PEG-COOH (MW 400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG-COOH (MW 400) can be used for fluorescent labeling and imaging .
|
-
- HY-D2795C
-
|
Fluorescent Dyes/Probes
|
FITC-PEG-COOH (MW 10000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG-COOH (MW 10000) can be used for fluorescent labeling and imaging .
|
-
- HY-D2795B
-
|
Fluorescent Dyes/Probes
|
FITC-PEG-COOH (MW 5000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a COOH. FITC-PEG-COOH (MW 5000) can be used for fluorescent labeling and imaging .
|
-
- HY-D1040
-
Cyanine 5.5 carboxylic acid
|
Fluorescent Dyes/Probes
|
Cy5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH can be used for bioimaging and disease diagnosis .
|
-
- HY-D1040A
-
Cyanine 5.5 carboxylic acid chloride
|
Fluorescent Dyes/Probes
|
Cy5.5-COOH (Cyanine 5.5 carboxylic acid) chloride is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH chloride possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH chloride can be used for bioimaging and disease diagnosis .
|
Cat. No. |
Product Name |
Type |
-
- HY-150352
-
|
Carbohydrates
|
Dextran-COOH is a dextran derivative with carboxyl (–COOH) functional groups introduced into the molecular chain. Dextran-COOH can be covalently coupled with a variety of bioactive molecules, drugs, small molecule ligands, fluorescent probes and other functional materials .
|
-
- HY-145790
-
|
Indicators
|
Difluorocyclooctyne-CH2-COOH is a Difluorinated cyclooctyne (DIFO) analogue that can be used for imaging glycans on live cells. Difluorinated cyclooctyne (DIFO) reagents rapidly reacts with azides in living cells without the need for copper catalysis . Difluorocyclooctyne-CH2-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W888710C
-
Folate-PEG-COOH (MW 1000)
|
Drug Delivery
|
FA-PEG-COOH (MW 1000) (Folate-PEG-COOH (MW 1000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710A
-
Folate-PEG-COOH (MW 400)
|
Drug Delivery
|
FA-PEG-COOH (MW 400) (Folate-PEG-COOH (MW 400)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710D
-
Folate-PEG-COOH (MW 2000)
|
Drug Delivery
|
FA-PEG-COOH (MW 2000) (Folate-PEG-COOH (MW 2000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710E
-
Folate-PEG-COOH (MW 3400)
|
Drug Delivery
|
FA-PEG-COOH (MW 3400) (Folate-PEG-COOH (MW 3400)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710B
-
Folate-PEG-COOH (MW 600)
|
Drug Delivery
|
FA-PEG-COOH (MW 600) (Folate-PEG-COOH (MW 600)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710H
-
Folate-PEG-COOH (MW 5000)
|
Drug Delivery
|
FA-PEG-COOH (MW 5000) (Folate-PEG-COOH (MW 5000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-W888710I
-
Folate-PEG-COOH (MW 10000)
|
Drug Delivery
|
FA-PEG-COOH (MW 10000) (Folate-PEG-COOH (MW 10000)) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .
|
-
- HY-168941A
-
|
3D Bioprinting
|
HS-PEG-COOH (Mn 3500) is a bi-functional PEG derivative. HS-PEG-COOH (Mn 3500) is used to synthesize PEG hydrogels .
|
-
- HY-168941
-
|
3D Bioprinting
|
HS-PEG-COOH (Mn 7500) is a bi-functional PEG derivative. HS-PEG-COOH (Mn 7500) is used to synthesize PEG hydrogels .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1170
-
Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
|
Opioid Receptor
|
Neurological Disease
|
N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
|
-
- HY-P10973
-
|
CXCR
ERK
|
Cancer
|
Peptide R analogue 10 (compound 10) is an analog of the CXCR4 antagonist peptide Peptide R (HY-P4111) with stronger antagonistic potency, specificity and plasma stability. Peptide R analogue 10 can inhibit CXCL12-mediated cell migration, ERK phosphorylation and CXCR4 internalization. Peptide R analogue 10 can be used in the study of CXCR4 overexpressing leukemia and colon cancer .
|
-
- HY-P11011
-
Pep R54; CXCR4 antagonist peptide 19
|
CXCR
|
Cancer
|
Peptide R54 (Pep R54; CXCR4 antagonist peptide 19) is an antagonistic peptide targeting CXCR4 with significant anticancer activity. Peptide R54 inhibits CXCR4-dependent cell migration, epithelial-mesenchymal transition, and lung metastasis development, with better serum stability and higher CXCR4 affinity than the lead compound (IC50=20 nM). Peptide R54 synergizes with anti-PD-1 therapy to exert anti-tumor activity in vivo, enhances granzyme activity, and reduces infiltration of Foxp3 cells. Peptide R54 can be used in the study of colon cancer, ovarian cancer, and melanoma .
|
-
- HY-P10964
-
|
GHSR
|
Endocrinology
|
Tezusomant is a growth hormone receptor antagonist. Tezusomant is promising for research of diseases such as acromegaly caused by excessive growth hormone secretion .
|
-
- HY-P5568
-
RP 71955
|
HIV
|
Infection
|
RP 71955 is an antimicrobial peptide against HIV-1 .
|
-
- HY-P10940
-
|
Peptides
|
Others
|
Ac-RFAAKAA-COOH is a heptapeptide with one reactive Lys residue. Ac-RFAAKAA-COOH can be used for detecting skin sensitizing components in cosmetics and other substances
|
-
- HY-P10940A
-
|
Peptides
|
Others
|
Ac-RFAAKAA-COOH TFA is a heptapeptide with one reactive Lys residue. Ac-RFAAKAA-COOH TFA can be used for detecting skin sensitizing components in cosmetics and other substances .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
|
Classification |
-
- HY-156492
-
|
|
ADC Synthesis
Tetrazine
|
Me-Tet-PEG4-COOH is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-151790
-
|
|
Alkynes
|
Alkyne-SS-COOH is a click chemistry reagent containing an alkyne group. Alkyne-SS-COOH can be used for the research of various biochemical .
|
-
- HY-156494
-
|
|
ADC Synthesis
Tetrazine
|
Me-Tet-PEG9-COOH is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156475
-
|
|
Tetrazine
ADC Synthesis
|
Me-Tet-PEG2-COOH is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-COOH can use its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156493
-
|
|
ADC Synthesis
Tetrazine
|
Me-Tet-PEG5-COOH is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-COOH can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
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