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Results for "

PEP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Antibiotic (1) Apoptosis (2) Biochemical Assay Reagents (5) CXCR (1) Endogenous Metabolite (2) FGFR (1) Fluorescent Dye (1) Glycoprotein VI (1) iGluR (2) Interleukin Related (2) Liposome (5) NO Synthase (2) PCSK9 (2) Peptide-Drug Conjugates (PDCs) (1) PKC (5) Prolyl Endopeptidase (PREP) (10) Pyroptosis (1) Pyruvate Kinase (1) RABV (1) Radionuclide-Drug Conjugates (RDCs) (1) Reference Standards (2) Small Interfering RNA (siRNA) (6)
By Research Areas:	Cancer (16) Cardiovascular Disease (2) Infection (3) Inflammation/Immunology (3) Metabolic Disease (3) Neurological Disease (14)
Click Chemistry:	Azide (1)
Oligonucleotides:	Pegylated Lipids (3) Mouse Pre-designed siRNA Sets (3) Human Pre-designed siRNA Sets (3) siRNAs (6)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5366

PEP1	Liposome	Others
PEP1 is a biological active peptide. (PEP1 binds to POPC SLBs at Low Concentration, High Concentration of PEP1 Leads to POPC SLBs Lysis)

HY-P1848

Pep-1 (uncapped)	Interleukin Related	Cancer
Pep-1 (uncapped) is a specific ligand of IL-13Ra2. Pep-1 (uncapped) exerts cell penetrating activity through receptor-mediated endocytosis, can cross the blood-tumor barrier (BTB) and target glioma cells. Pep-1 (uncapped) can enhance the uptake of nanoparticles by tumor cells and enhance the cell penetration ability of nanoparticles, and can be used to develop targeted drug delivery systems for glioma .

HY-P2276

Pep2-8	PCSK9	Cancer
Pep2-8 is a PCSK9 inhibitor with a binding K_D of 0.7 μM and an IC₅₀ of 1.4 μM .

HY-P3496

Pep19-2.5	Pyroptosis	Inflammation/Immunology
Pep19-2.5 is an synthetic and antitoxin peptide, blocks the intracellular endotoxin signaling cascade. Pep19-2.5 inhibits signaling of lipopeptides (LP) and lipopolysaccharides (LPS) mediated by transmembrane and cytosolic pattern recognition receptors (PRRs). The signaling cascades lead to inflammation and cell pyroptosis .

HY-E70395

Prolyl endopeptidase PE; PEP	Biochemical Assay Reagents	Neurological Disease
Prolyl Endopeptidase, highly active in brain and other tissues, catabolizes proline-containing peptides such as substance P, neurotensin, luteinizing hormone-releasing hormone, thyrotropin releasing hormone, bradykinin and angiotensin II. Prolyl Endopeptidase can be used for study of neuropsychiatric diseases such as stress disorder, depression, and schizophrenia .

HY-P1055

Pep2-SVKE	iGluR	Neurological Disease
Pep2-SVKE is an inactive control peptide for pep2-SVKI (HY-P1056). Pep2-SVKE is an inhibitory peptide corresponding to the last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit. Pep2-SVKE does not block AMPA-mediated [ ³H]DA exocytosis. Pep2-SVKE does not bind to GRIP or PICK43 and does not block retention of PICK1 by GST-GluR2 and LTD ^{[1] [2] [3] [4] [5]}.

HY-P10630

Pep63	Amyloid-β	Neurological Disease
Pep63 is a neuroprotective peptide (VFQVRARTVA). Pep63 has a neuroprotective effect on synaptic plasticity and memory. Pep63 can competitively bind with Aβ1-42 oligomers, and can block Aβ fiber formation. Pep63 can be used for Alzheimer’s disease (AD) research .

HY-P10949

pep-10L peptide	Glycoprotein VI	Cardiovascular Disease
Pep-10L peptide is a glycoprotein VI (GPVI) antagonist with K_i values of 180, 225, and 179 μM for CPR, GPO-1, and Type 1 collagen, respectively. Pep-10L peptide has anti-thrombotic effects .

HY-P1057

Pep4c	iGluR	Neurological Disease
Pep4c is an inactive control peptide for Pep2m (HY-P1058). Pep4c lacks functional activity to disrupt Protein Interacting with C Kinase 1 (PICK1)-AMPA receptor (GluA2) or N-ethylmaleimide-sensitive factor (NSF)-GluA2 interactions. Pep4c is used as a negative control in experiments to validate the specificity of Pep2m's effects on AMPA receptor trafficking and synaptic plasticity ^{[1] [2] [3] [4] [5] [6]}.

HY-P1399

Pep2m, myristoylated Myr-PEP2m	PKC	Neurological Disease
Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .

HY-P2276A

Pep2-8 TFA	PCSK9	Cardiovascular Disease Others
Pep2-8 is a peptide which has enhanced the antagonistic activity of proprotein convertase subtilin/ kexin 9 type (PCSK9) .

HY-P10870

Pep1-DNP conjugate 9	Peptide-Drug Conjugates (PDCs) FGFR Apoptosis	Cancer
Pep1-DNP conjugate 9 is a functionalized peptide which is composed of the DNP-Hapten and the FGFR1 binding peptide. Pep1-DNP conjugate 9 exhibits good affinity to FGFR1 with K_D of 5.01 μM. Pep1-DNP conjugate 9 recruits anti-DNP antibodies to the surface of FGFR1-positive cells, inhibits the FGF2-induced proliferation in rat skeletal myoblast cells, and induces apoptosis. Pep1-DNP conjugate 9 exhibits antitumor efficacy in mouse models .

HY-P1054

pep2-EVKI YNVYGIEEVKI	PKC	Neurological Disease
pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively blocks PICK1 interactions, caused the opposite effects on synaptic AMPAR function to PICK1 expression .

HY-P1399A

Pep2m, myristoylated TFA Myr-PEP2m TFA	PKC	Neurological Disease
Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .

HY-E70435

Prolylendopeptidase, myxococcus xanthus PEP-Mx	Biochemical Assay Reagents	Others
Prolylendopeptidase, myxococcus xanthus (PEP-Mx) is an endopeptidase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-106364

Peplomycin Bleomycin PEP; PEPleomycin	Antibiotic	Cancer
Peplomycin (Bleomycin PEP; Pepleomycin) is an antibiotic analogue of Bleomycin (HY-108345), with high antitumor effect and less pulmonary toxicity. Peplomycin induce apoptosis in oral squamous carcinoma cell line SSCKN cells and pulmonary fibrosis in rats .

HY-D1313

PEP azide	Fluorescent Dye	Others
PEP azide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-P11011

Peptide R54 PEP R54; CXCR4 antagonist PEPtide 19	CXCR	Cancer
Peptide R54 (Pep R54; CXCR4 antagonist peptide 19) is an antagonistic peptide targeting CXCR4 with significant anticancer activity. Peptide R54 inhibits CXCR4-dependent cell migration, epithelial-mesenchymal transition, and lung metastasis development, with better serum stability and higher CXCR4 affinity than the lead compound (IC₅₀=20 nM). Peptide R54 synergizes with anti-PD-1 therapy to exert anti-tumor activity in vivo, enhances granzyme activity, and reduces infiltration of Foxp3 cells. Peptide R54 can be used in the study of colon cancer, ovarian cancer, and melanoma .

HY-B0719

Ingenol Mebutate 4 Publications Verification Ingenol 3-angelate; PEP005	PKC	Inflammation/Immunology Cancer
Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with K_is of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.

HY-B0719R

Ingenol Mebutate (Standard) Ingenol 3-angelate (Standard); PEP005 (Standard)	Reference Standards PKC	Inflammation/Immunology Cancer
Ingenol Mebutate (Standard) is the analytical standard of Ingenol Mebutate. This product is intended for research and analytical applications. Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with K_is of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.

HY-137220

Z-Gly-Pro-pNA	Prolyl Endopeptidase (PREP)	Others
Z-Gly-Pro-pNA is a substrate for measuring prolyl endopeptidase (PEP) inhibitory activity .

HY-P10292

*NOTA-Pep-1L*	Radionuclide-Drug Conjugates (RDCs) Interleukin Related	Cancer
NOTA-Pep-1L specifically targets the IL13RA2 receptor for tumor imaging . NOTA-Pep-1L can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-125432

Poststatin	Prolyl Endopeptidase (PREP)	Metabolic Disease
Poststatin is a pecific prolyl endopeptidase (PEP) inhibitor. Poststatin inhibits bradykinin-degrading enzymes in rat urine .

HY-172273

DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY	Liposome	Cancer
DSPE-PEG1000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-M2pep can be used for drug delivery .

HY-172273B

DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY	Liposome	Cancer
DSPE-PEG5000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-M2pep can be used for drug delivery .

HY-172273A

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY	Liposome	Cancer
DSPE-PEG2000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-M2pep can be used for drug delivery .

HY-172273C

DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY	Liposome	Cancer
DSPE-PEG3400-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-M2pep can be used for drug delivery .

HY-P0184

Camstatin	NO Synthase	Neurological Disease
Camstatin, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase .

HY-P0184A

Camstatin TFA	NO Synthase	Neurological Disease
Camstatin TFA, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase .

HY-19123

Z-321	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-321 is a prolylendopeptidase (PEP) inhibitor.

HY-P4490

Suc-Ala-Pro-pNA	Prolyl Endopeptidase (PREP)	Others
Suc-Ala-Pro-pNA is a peptide that serves as a substrate to detect the activity and stability of prolyl endopeptidase (PEP) .

HY-113167

2-Phosphoglyceric acid DL-2-phosphoglyceric acid	Endogenous Metabolite	Metabolic Disease
2-Phosphoglyceric acid (DL-2-phosphoglyceric acid) is a glycolysis substrate. It is catalyzed by enolase into phosphoenolpyruvate (PEP) .

HY-RS11083

PREP Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PREP Human Pre-designed siRNA Set A contains three designed siRNAs for PREP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PREP Human Pre-designed siRNA Set A PREP Human Pre-designed siRNA Set A

HY-15114

S 17092 S 17092-1	Prolyl Endopeptidase (PREP) Apoptosis	Neurological Disease
S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC₅₀ of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging .

HY-113951

Prolyl Endopeptidase Inhibitor 1 Boc-Pro-prolinal; (Boc)-Prolyl-prolinal	Prolyl Endopeptidase (PREP)	Neurological Disease
Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) is a potent *prolyl endopeptidase (PEP; PE)* inhibitor, with a K_i value of 15 nM. Prolyl Endopeptidase Inhibitor 1 has anti-amnesic effect .

HY-162452

Prolyl endopeptidase inhibitor 2	Prolyl Endopeptidase (PREP)	Neurological Disease
Prolyl endopeptidase inhibitor 2 (Compound 8) was a proline endopeptidase (PEP) inhibitor with IC₅₀ value 31.11 μM. Prolyl endopeptidase inhibitor 2 can be used in the study of neurodegenerative diseases .

HY-RS17516

Ptpn22 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ptpn22 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn22 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ptpn22 Mouse Pre-designed siRNA Set A Ptpn22 Mouse Pre-designed siRNA Set A

HY-RS17253

Fndc5 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fndc5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fndc5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fndc5 Mouse Pre-designed siRNA Set A Fndc5 Mouse Pre-designed siRNA Set A

HY-N15009

Kynapcin-13	Prolyl Endopeptidase (PREP)	Infection
Kynapcin-13 can non-competitively inhibit the activity of prolyl endopeptidase (PEP) with an IC₅₀ of 76.80 μM. Kynapcin-13 has a little inhibitory effect on other serine proteases .

HY-N15010

Kynapcin-28	Prolyl Endopeptidase (PREP)	Infection
Kynapcin-28 can non-competitively inhibit the activity of prolyl endopeptidase (PEP) with an IC₅₀ of 76.80 μM. Kynapcin-28 has a little inhibitory effect on other serine proteases .

HY-P99792

Ormutivimab NM57; rhRIG	RABV	Infection
Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model .

HY-110124

ML202	Pyruvate Kinase	Cancer
ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), which can affect the cooperativity of phosphoenolpyruvate (PEP) binding, while adenosine diphosphate (ADP) binding almost no effect .

HY-148331

Z-Thioprolyl-Thioproline	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Thioprolyl-Thioproline is a bovine brain prolyl endopeptidase (PEP) inhibitor (IC₅₀=16 µM; K_i=37 µM). Z-Thioprolyl-Thioproline is used in the study of neurological disorders such as memory disorders and cognitive disorders .

HY-RS17643

Prep Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Prep Mouse Pre-designed siRNA Set A contains three designed siRNAs for Prep gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Prep Mouse Pre-designed siRNA Set A Prep Mouse Pre-designed siRNA Set A

HY-141436

Sucrosofate potassium Sucrose octasulfate potassium	Biochemical Assay Reagents	Cancer
Sucrosofate (Sucrose octasulfate) potassium is a sucrose acid that can be used to prepare liposomes to deliver Irinotecan (HY-16562). Irinotecan is an inhibitor of topoisomerase Topo I and is commonly used in colon and rectal cancer research. Sucrosofate nanoliposome preparation loaded with Irinotecan, also known as PEP02 or MM-398 .

HY-W712327

D-Xylulose 5-phosphate sodium	Biochemical Assay Reagents	Others
D-Xylulose 5-phosphate (sodium) is a pentose phosphate ester and an essential intermediate metabolite in the pentose phosphate pathway (PPP) and the non-oxidative phase of the pentose phosphate pathway. D-xylulose-5-phosphate can be efficiently synthesized through the phosphorylation of D-xylulose catalyzed by D-xylulokinase (XKS1 from Saccharomyces cerevisiae), with ATP regeneration facilitated by the phosphoenolpyruvate (PEP)/pyruvate kinase (PK) system .

HY-141436R

Sucrosofate potassium (Standard) Sucrose octasulfate potassium (Standard)	Biochemical Assay Reagents Reference Standards	Cancer
Sucrosofate (potassium) (Standard) is the analytical standard of Sucrosofate (potassium). This product is intended for research and analytical applications. Sucrosofate (Sucrose octasulfate) potassium is a sucrose acid that can be used to prepare liposomes to deliver Irinotecan (HY-16562). Irinotecan is an inhibitor of topoisomerase Topo I and is commonly used in colon and rectal cancer research. Sucrosofate nanoliposome preparation loaded with Irinotecan, also known as PEP02 or MM-398 .

HY-P2819A

Phosphofructokinase,Bacillus stearothermophilus	Endogenous Metabolite	Metabolic Disease
Phosphofructokinase from Bacillus stearothermophilus is a key enzyme in sugar metabolism that catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate during glycolysis. The enzyme's ability to bind fructose-6-phosphate can be inhibited by phosphoenolpyruvate (PEP), thereby regulating the rate of glycolysis. Phosphofructokinase from Bacillus stearothermophilus can be used for the measurement of fructose-6-phosphate levels .

HY-RS11424

PTPN22 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PTPN22 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN22 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PTPN22 Human Pre-designed siRNA Set A PTPN22 Human Pre-designed siRNA Set A

HY-RS09965

PAEP Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PAEP Human Pre-designed siRNA Set A contains three designed siRNAs for PAEP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PAEP Human Pre-designed siRNA Set A PAEP Human Pre-designed siRNA Set A

Cat. No.	Product Name	Type

HY-D1313

PEP azide

Fluorescent Dyes/Probes

PEP azide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

Cat. No.	Product Name	Type

HY-172273

DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY	Drug Delivery
DSPE-PEG1000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-M2pep can be used for drug delivery .

HY-172273B

DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY	Drug Delivery
DSPE-PEG5000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-M2pep can be used for drug delivery .

HY-172273A

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY	Drug Delivery
DSPE-PEG2000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-M2pep can be used for drug delivery .

HY-172273C

DSPE-PEG3400-Mal-Cys-YEQDPWGVKWWY	Drug Delivery
DSPE-PEG3400-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG3400-M2pep can be used for drug delivery .

Cat. No.	Product Name	Target	Research Area

HY-P5366

PEP1	Liposome	Others
PEP1 is a biological active peptide. (PEP1 binds to POPC SLBs at Low Concentration, High Concentration of PEP1 Leads to POPC SLBs Lysis)

HY-P1848

Pep-1 (uncapped)	Interleukin Related	Cancer
Pep-1 (uncapped) is a specific ligand of IL-13Ra2. Pep-1 (uncapped) exerts cell penetrating activity through receptor-mediated endocytosis, can cross the blood-tumor barrier (BTB) and target glioma cells. Pep-1 (uncapped) can enhance the uptake of nanoparticles by tumor cells and enhance the cell penetration ability of nanoparticles, and can be used to develop targeted drug delivery systems for glioma .

HY-P4119A

Pep-1-Cysteamine TFA	Peptides	Others
Pep-1-Cysteamine TFA is a chimeric cell-penetrating peptide (CPP) with a primary amphipathicity. Pep-1-Cysteamine TFA has the ability to translocate across biological membranes and introduce active proteins inside cells .

HY-P2276

Pep2-8	PCSK9	Cancer
Pep2-8 is a PCSK9 inhibitor with a binding K_D of 0.7 μM and an IC₅₀ of 1.4 μM .

HY-P3496

Pep19-2.5	Pyroptosis	Inflammation/Immunology
Pep19-2.5 is an synthetic and antitoxin peptide, blocks the intracellular endotoxin signaling cascade. Pep19-2.5 inhibits signaling of lipopeptides (LP) and lipopolysaccharides (LPS) mediated by transmembrane and cytosolic pattern recognition receptors (PRRs). The signaling cascades lead to inflammation and cell pyroptosis .

HY-P1055

Pep2-SVKE	iGluR	Neurological Disease
Pep2-SVKE is an inactive control peptide for pep2-SVKI (HY-P1056). Pep2-SVKE is an inhibitory peptide corresponding to the last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit. Pep2-SVKE does not block AMPA-mediated [ ³H]DA exocytosis. Pep2-SVKE does not bind to GRIP or PICK43 and does not block retention of PICK1 by GST-GluR2 and LTD ^{[1] [2] [3] [4] [5]}.

HY-P4119

Pep-1-Cysteamine	Peptides	Others
Pep-1-Cysteamine is a chimeric cell-penetrating peptide (CPP) with a primary amphipathicity. Pep-1-Cysteamine has the ability to translocate across biological membranes and introduce active proteins inside cells .

HY-P10630

Pep63	Amyloid-β	Neurological Disease
Pep63 is a neuroprotective peptide (VFQVRARTVA). Pep63 has a neuroprotective effect on synaptic plasticity and memory. Pep63 can competitively bind with Aβ1-42 oligomers, and can block Aβ fiber formation. Pep63 can be used for Alzheimer’s disease (AD) research .

HY-P10949

pep-10L peptide	Glycoprotein VI	Cardiovascular Disease
Pep-10L peptide is a glycoprotein VI (GPVI) antagonist with K_i values of 180, 225, and 179 μM for CPR, GPO-1, and Type 1 collagen, respectively. Pep-10L peptide has anti-thrombotic effects .

HY-P1057

Pep4c	iGluR	Neurological Disease
Pep4c is an inactive control peptide for Pep2m (HY-P1058). Pep4c lacks functional activity to disrupt Protein Interacting with C Kinase 1 (PICK1)-AMPA receptor (GluA2) or N-ethylmaleimide-sensitive factor (NSF)-GluA2 interactions. Pep4c is used as a negative control in experiments to validate the specificity of Pep2m's effects on AMPA receptor trafficking and synaptic plasticity ^{[1] [2] [3] [4] [5] [6]}.

HY-P1399

Pep2m, myristoylated Myr-PEP2m	PKC	Neurological Disease
Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .

HY-P2276A

Pep2-8 TFA	PCSK9	Cardiovascular Disease Others
Pep2-8 is a peptide which has enhanced the antagonistic activity of proprotein convertase subtilin/ kexin 9 type (PCSK9) .

HY-P10870

Pep1-DNP conjugate 9	Peptide-Drug Conjugates (PDCs) FGFR Apoptosis	Cancer
Pep1-DNP conjugate 9 is a functionalized peptide which is composed of the DNP-Hapten and the FGFR1 binding peptide. Pep1-DNP conjugate 9 exhibits good affinity to FGFR1 with K_D of 5.01 μM. Pep1-DNP conjugate 9 recruits anti-DNP antibodies to the surface of FGFR1-positive cells, inhibits the FGF2-induced proliferation in rat skeletal myoblast cells, and induces apoptosis. Pep1-DNP conjugate 9 exhibits antitumor efficacy in mouse models .

HY-P1054

pep2-EVKI YNVYGIEEVKI	PKC	Neurological Disease
pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively blocks PICK1 interactions, caused the opposite effects on synaptic AMPAR function to PICK1 expression .

HY-P1399A

Pep2m, myristoylated TFA Myr-PEP2m TFA	PKC	Neurological Disease
Pep2m, myristoylated TFA (Myr-Pep2m TFA) is a cell-permeable peptide. Pep2m, myristoylated TFA can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC) .

HY-P10374

Pep42	Peptides	Cancer
Pep42, a cyclic peptide ligand of GPR78, internalizes selectively into highly metastatic human melanoma cells through a receptor-mediated process .

HY-P11011

Peptide R54 PEP R54; CXCR4 antagonist PEPtide 19	CXCR	Cancer
Peptide R54 (Pep R54; CXCR4 antagonist peptide 19) is an antagonistic peptide targeting CXCR4 with significant anticancer activity. Peptide R54 inhibits CXCR4-dependent cell migration, epithelial-mesenchymal transition, and lung metastasis development, with better serum stability and higher CXCR4 affinity than the lead compound (IC₅₀=20 nM). Peptide R54 synergizes with anti-PD-1 therapy to exert anti-tumor activity in vivo, enhances granzyme activity, and reduces infiltration of Foxp3 cells. Peptide R54 can be used in the study of colon cancer, ovarian cancer, and melanoma .

HY-113871

*R-PEP-27*	Peptides	Others
R-PEP-27 is an active compound.

HY-P10292

*NOTA-Pep-1L*	Radionuclide-Drug Conjugates (RDCs) Interleukin Related	Cancer
NOTA-Pep-1L specifically targets the IL13RA2 receptor for tumor imaging . NOTA-Pep-1L can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-125432

Poststatin	Prolyl Endopeptidase (PREP)	Metabolic Disease
Poststatin is a pecific prolyl endopeptidase (PEP) inhibitor. Poststatin inhibits bradykinin-degrading enzymes in rat urine .

HY-P0184

Camstatin	NO Synthase	Neurological Disease
Camstatin, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase .

HY-P0184A

Camstatin TFA	NO Synthase	Neurological Disease
Camstatin TFA, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase .

HY-P4490

Suc-Ala-Pro-pNA	Prolyl Endopeptidase (PREP)	Others
Suc-Ala-Pro-pNA is a peptide that serves as a substrate to detect the activity and stability of prolyl endopeptidase (PEP) .

Cat. No.	Product Name	Target	Research Area

HY-P99792

Ormutivimab NM57; rhRIG	RABV	Infection
Ormutivimab (rhRIG) is a recombinant human monoclonal antibody, targeting rabies virus. Ormutivimab neutralizes a variety of rabies virus strains. Ormutivimab exhibits potent potency against rabies post-exposure prophylaxis (PEP) model .

Species:	Human (3) Mouse (1) E.coli (1)
Tag:	His (3) SUMO (1) Tag Free (2) Strep (1)
Source:	Sf9 insect cells (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P73692

	Prolyl Endopeptidase/PREP Protein, Mouse (sf9, His) Prolyl endoPEPtidase; PE; Prep; PEP	Mouse	Sf9 insect cells
	The prolyl endopeptidase (PREP) protein is an enzyme capable of cleaving peptide bonds at the C-terminus of prolyl residues within peptides, particularly peptides up to about 30 amino acids in length.This enzymatic activity suggests a role for PREP in selective processing of peptides, particularly toward proline-containing substrates.Prolyl Endopeptidase/PREP Protein, Mouse (sf9, His) is the recombinant mouse-derived Prolyl Endopeptidase/PREP protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P703584

	PREP Protein, Human PEP	Human	E. coli
	PREP Protein, Human is the recombinant human-derived PREP, expressed by E. coli , with tag Free labeled tag. ,

HY-P71458

	PpsA Protein, E.coli (His-SUMO) ppsA; pps; b1702; JW1692Phosphoenolpyruvate synthase; PEP synthase; EC 2.7.9.2; Pyruvate; water dikinase	E.coli	E. coli
	The PpsA protein plays a crucial role in cellular metabolism by catalyzing the conversion of pyruvate to phosphoenolpyruvate, a key step in glycolysis and gluconeogenesis. This enzyme activity is the basis for the interconversion of metabolic intermediates and contributes to the regulation of intracellular energy production and utilization. PpsA Protein, E.coli (His-SUMO) is the recombinant E. coli-derived PpsA protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P702054

	Vps29 Protein, Human VPS29; Vacuolar protein sorting-associated protein 29; hVPS29; PEP11 homolog; Vesicle protein sorting 29	Human	E. coli
	The Vps29 protein is an important component of the reverse transcriptase cargo-selective complex (CSC), which prevents mispairing of transmembrane cargo proteins leading to lysosomal degradation. It coordinates retrograde transport from endosomes to the trans-Golgi network through distinct pathways involving the SNX-BAR, SNX3, and SNX27 retrosome complexes. Vps29 Protein, Human is the recombinant human-derived Vps29 protein, expressed by E. coli , with tag free.

HY-P702055

	Vps29 Protein, Human (His, StrepⅡ) VPS29; Vacuolar protein sorting-associated protein 29; hVPS29; PEP11 homolog; Vesicle protein sorting 29	Human	E. coli
	The Vps29 protein is an important component of the reverse transcriptase cargo-selective complex (CSC), which prevents mispairing of transmembrane cargo proteins leading to lysosomal degradation. It coordinates retrograde transport from endosomes to the trans-Golgi network through distinct pathways involving the SNX-BAR, SNX3, and SNX27 retrosome complexes. Vps29 Protein, Human (His, Strep) is the recombinant human-derived Vps29 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag.

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81801

	VPS26 Antibody (YA1546) HB58; Hbeta58; hVPS26; PEP8A; VPS 26; VPS26A	WB, ICC/IF, IP	Human, Mouse, Rat
	VPS26 Antibody (YA1546) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1546), targeting VPS26, with a predicted molecular weight of 38 kDa (observed band size: 38 kDa). VPS26 Antibody (YA1546) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

HY-P82700

	VPS18 Antibody (YA2445) hVPS18; PEP3; vps18	WB, ICC/IF, FC	Human, Mouse, Rat
	VPS18 Antibody (YA2445) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2445), targeting VPS18, with a predicted molecular weight of 110 kDa (observed band size: 100 kDa). VPS18 Antibody (YA2445) can be used for WB, ICC/IF, FC experiment in human, mouse, rat background.

HY-P82692

	VPS11 Antibody (YA2437) END1; hVPS11; PEP5; PP3476; RNF108; vps11	WB, IHC-P, FC	Human, Mouse
	VPS11 Antibody (YA2437) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2437), targeting VPS11, with a predicted molecular weight of 108 kDa (observed band size: 108 kDa). VPS11 Antibody (YA2437) can be used for WB, IHC-P, FC experiment in human, mouse background.

HY-P82448

	Glycodelin Antibody (YA2193) GdA; GdF; GdS; Glycodelin A; Glycodelin; Glycodelin F; Glycodelin S; PAEG; PAEP; PEG; PEP; Placental protein 14; PP14	WB	Human
	Glycodelin Antibody (YA2193) is a non-conjugated IgG antibody, targeting Glycodelin, with a predicted molecular weight of 21 kDa (observed band size: 24 kDa). Glycodelin Antibody (YA2193) can be used for WB experiment in human background.

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-D1313

PEP azide		Azide
PEP azide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

Cat. No.	Product Name		Classification

HY-172273

DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY		Pegylated Lipids
DSPE-PEG1000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-M2pep can be used for drug delivery .

HY-172273B

DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY		Pegylated Lipids
DSPE-PEG5000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-M2pep can be used for drug delivery .

HY-172273A

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY		Pegylated Lipids
DSPE-PEG2000-M2pep is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-M2pep can be used for drug delivery .

HY-RS11083

PREP Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PREP Human Pre-designed siRNA Set A contains three designed siRNAs for PREP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17516

Ptpn22 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ptpn22 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn22 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17253

Fndc5 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Fndc5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fndc5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17643

Prep Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Prep Mouse Pre-designed siRNA Set A contains three designed siRNAs for Prep gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS11424

PTPN22 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PTPN22 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN22 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS09965

PAEP Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PAEP Human Pre-designed siRNA Set A contains three designed siRNAs for PAEP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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