Focused and target libraries

Focused and target libraries( 7 )

• Cysteine Protease Focused Library

  A compound library can be used for the efficient discovery of novel cysteine protease inhibitors.

  9000 compounds HY-L925

• CNS MPO Lead-like Library

  The CNS multi-parameter optimization (MPO) tool can probabilistically evaluates drug properties, covering ADME, BBB penetration, and safety. This compound library is screened for molecules with an MPO score >5.

  24,816compounds HY-L920

• RNA Binding Library

  5,000 small molecule compounds with potential RNA interaction activity. Powered by AI models (AUROC of 0.82 and high accuracy with ACC of 0.76).

  5,619compounds HY-L917

• Ion Channel Lead-like Compound Library

  An ion channel lead-like compound library constructed through ligand-based AI screening models, with potential hERG toxic compounds excluded.

  9000compounds HY-L923

• MCE CNS BBB Lead-like Library

  The CNS BBB Library is a collection of blood-brain barrier permeable compounds predicted by AI algorithms, with predicted value greater than 0.75.

  27,503compounds HY-L919

• GPCR Targeted Diversity Library

  A compound library can be used for efficient discovery of novel molecule targeting GPCR protein.

  7000compounds HY-L928

• Norepinephrine Transporter (NET) Compound Library

  Norepinephrine Transporter (NET) Compound Library is obtained by virtual screening based on HY-L901 50K Diversity Library. It can be applied in new drug discovery targeting noradrenaline transporter (NET).

  650compounds HY-L906