2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK FLT3
  4. SB1578

SB1578 (CT-1578) is a selective JAK2 and FLT3 inhibitor with an IC50 of 46 nM and 60 nM, respectively. SB1578 exhibits high selectivity for other kinase targets. SB1578 can be used for the study of non-oncology indication rheumatoid arthritis.

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SB1578

SB1578 Chemical Structure

CAS No. : 937273-04-6

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SB1578 Related Antibodies

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Description

SB1578 (CT-1578) is a selective JAK2 and FLT3 inhibitor with an IC50 of 46 nM and 60 nM, respectively. SB1578 exhibits high selectivity for other kinase targets. SB1578 can be used for the study of non-oncology indication rheumatoid arthritis[1].

IC50 & Target[1]

JAK2

46 nM (IC50)

FLT3

60 nM (IC50)

Molecular Weight

462.54

Formula

C26H30N4O4
CAS No.
SMILES

N1(CCCC1)CCOC2=CC=C3C=C2COC/C=C/COCC4=CC=C(O4)C5=CC=N/C(N5)=N/3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SB1578 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB1578937273-04-6CT-1578SB 1578SB-1578CT1578CT 1578JAKFLT3Janus kinaseCluster of differentiation antigen 135CD135Fms like tyrosine kinase 3JAK2 and FLT3 inhibitornon-oncology indication rheumatoid arthritisInhibitorinhibitorinhibit

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