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  4. TSPAN8 Protein, Mouse (HEK293, His)

TSPAN8 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TSPAN8 protein, expressed by HEK293, with N-His tag.

For research use only. We do not sell to patients.

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Description

TSPAN8 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TSPAN8 protein, expressed by HEK293, with N-His tag.
Background

TSPAN8 plays an important role in promoting tumor metastasis by activating the EGFR/AKT pathway[1].
TSPAN8 alleviates high-glucose-induced autophagy and apoptosis in HK-2 cells by targeting mTORC2[2].
TSPAN8 forms protein complexes mediated by TSPAN8 through interactions with itself and various other cell signaling molecules. These protein complexes help to construct tetraspan-rich microdomains (TEMs), which effectively mediate intracellular signaling transduction. In addition, TSPAN8 plays a crucial role in regulating biological functions such as leukocyte migration, angiogenesis, and wound repair[3].
Species

Mouse
Source

HEK293
Tag

N-His
Accession

Q8R3G9-1 (G106-N203)
Gene ID

216350
Molecular Construction
N-term
His
(G106-N203)
Accession # Q8R3G9-1
C-term
Synonyms
Tetraspanin-8; Tspan8; Tspan-8
Predicted Molecular Mass
12.8 kDa
Molecular Weight

Approximately 15-19 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Glycosylation
Yes
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

TSPAN8 Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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TSPAN8 Protein, Mouse (HEK293, His)
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