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  4. TEAD2 Protein, Human (sf9, Depalmitoylated)

TEAD2 Protein, Human (sf9, Depalmitoylated)

Cat. No.: HY-P703247
Handling Instructions Technical Support

TEAD2 Protein, Human (sf9, Depalmitoylated) is the recombinant human-derived TEAD2 protein, expressed by Sf9 insect cells, with tag free tag.

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

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100 μg   Get quote  

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Description

TEAD2 Protein, Human (sf9, Depalmitoylated) is the recombinant human-derived TEAD2 protein, expressed by Sf9 insect cells, with tag free tag.
Background

TEAD2 is a transcription factor that plays a key role in the Hippo signaling pathway, which controls organ size and suppresses tumors by restricting proliferation and promoting apoptosis. The pathway's core involves a kinase cascade where MST1/MST2, complexed with SAV1, phosphorylates and activates LATS1/2 in complex with MOB1, leading to the phosphorylation and inactivation of the oncoproteins YAP1 and WWTR1/TAZ. TEAD2 mediates the gene expression of YAP1 and WWTR1/TAZ, regulating cell proliferation, migration, and epithelial-mesenchymal transition (EMT) induction. It binds to SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and may be involved in neural development gene regulation. Additionally, TEAD2 binds to the M-CAT motif.
Species

Human
Source

Sf9 insect cells
Tag

Tag Free
Accession

Q15562-1 (A217-D447)
Gene ID

8463
Protein Length

Partial
Synonyms
TEF4
Predicted Molecular Mass
26.4 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

TEAD2 Protein, Human (sf9, Depalmitoylated) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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