2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Neurotrophic Factors
  5. Neuropoietin
  6. Neuropoietin Protein, Mouse

Neurogenin, a protein associated with elevated platelet counts and splenomegaly, is involved in neuronal precursor development and maturation. By binding to the CNTF receptor complex (including CNTF alpha chain, LIFR and IL6ST), neurogenin may affect signaling pathways related to cell differentiation. Neuropoietin Protein, Mouse is the recombinant mouse-derived Neuropoietin protein, expressed by E. coli , with tag free.

For research use only. We do not sell to patients.

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Description

Neurogenin, a protein associated with elevated platelet counts and splenomegaly, is involved in neuronal precursor development and maturation. By binding to the CNTF receptor complex (including CNTF alpha chain, LIFR and IL6ST), neurogenin may affect signaling pathways related to cell differentiation. Neuropoietin Protein, Mouse is the recombinant mouse-derived Neuropoietin protein, expressed by E. coli , with tag free.
Background

Neuropoietin, a protein associated with increased platelet count and splenomegaly, potentially plays a crucial role in neuronal precursor development and maturation. It exerts its effects by binding to the tripartite CNTF receptor complex, which comprises the CNTF alpha chain, LIFR, and IL6ST. This interaction, observed in vitro, suggests Neuropoietin's involvement in signaling pathways associated with cellular differentiation and maturation processes. The protein's dual roles in platelet regulation and neurodevelopment underscore its versatility and potential significance in diverse physiological contexts.
Species

Mouse
Source

E. coli
Tag

Tag Free
Accession

P83714 (A23-A204)
Gene ID

244218  [NCBI]
Molecular Construction
N-term
Neuropoietin (A23-A204)
Accession # P83714
C-term
Protein Length

Full Length of Mature Protein
Synonyms
Cardiotrophin-2; Ctf2; CT-2; Neuropoietin; Np; Gm494
Predicted Molecular Mass
19.7 kDa
Molecular Weight

Approximately 20 kDa, based on SDS-PAGE under reducing conditions.
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Neuropoietin Protein, Mouse Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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