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  4. MMP-8
  5. MMP-8 Protein, Mouse (242a.a, HEK293, His)

MMP-8 protein degrades different fibrillar collagens, such as type I, II, and III. It is implicated in the breakdown of collagen fibers during uterine involution. MMP-8 Protein, Mouse (242a.a, HEK293, His) is the recombinant mouse-derived MMP-8 protein, expressed by HEK293, with C-His labeled tag.

For research use only. We do not sell to patients.

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50 μg Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
100 μg   Get quote  
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  • Biological Activity

  • Technical Parameters

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Description

MMP-8 protein degrades different fibrillar collagens, such as type I, II, and III. It is implicated in the breakdown of collagen fibers during uterine involution. MMP-8 Protein, Mouse (242a.a, HEK293, His) is the recombinant mouse-derived MMP-8 protein, expressed by HEK293, with C-His labeled tag.

Background

MMP-8 protein has the capacity to degrade various types of fibrillar collagens, including type I, II, and III. It is suggested that MMP-8 may be involved in the breakdown of collagen fibers during the process of uterine involution.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

O70138 (F21-G262)

Gene ID

17394

Molecular Construction
N-term
MMP-8 (F21-G262)
Accession # O70138
His
C-term
Synonyms
Neutrophil collagenase; MMP-8; PMNL-CL; CLG1
Predicted Molecular Mass
28.9 kDa.
Molecular Weight

Approximately 35-40 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

Glycosylation
Yes
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Appearance

Solution.

Formulation

Supplied as 0.2 μm filtered solution of 25 mM MES, 150 mM NaCl, 20% Glycerol, pH5.5 with trehalose as protectant.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

MMP-8 Protein, Mouse (242a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
MMP-8 Protein, Mouse (242a.a, HEK293, His)
Cat. No.:
HY-P704792
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