GPR87 Protein-VLP, Human (HEK293)

GPR87, a lysophosphatidic acid (LPA) receptor, crucially activates p53/TP53-dependent survival pathways in response to DNA damage. Its interaction with LPA plays a key role in mediating cellular responses to DNA damage, highlighting its significance in cell survival and DNA damage repair processes. GPR87 Protein-VLP, Human (HEK293) is the recombinant human-derived GPR87 protein, expressed by HEK293, with tag free.Formed in HEK293 cultures, these VLPs concentrate membrane proteins on the cell surface, producing high-concentration proteins ideal for immunization and antibody screening. Given the high immunogenicity of VLPs, the immunization protocol such as antigen dose, schedule, and adjuvant, requires optimization. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.

GPR87, serving as a receptor for lysophosphatidic acid (LPA), plays a crucial role in p53/TP53-dependent survival pathways activated in response to DNA damage. The receptor's engagement with LPA is instrumental in mediating cellular responses to DNA damage, emphasizing its significance in processes related to cell survival and DNA damage repair.

Human

HEK293

Tag Free

Q9BY21 (M1-V358)

53836

Full Length

Solution

Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.