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  4. GIPR Protein, Cynomolgus (HEK293, His, Avi)

GIPR Protein, Cynomolgus (HEK293, His, Avi)

Cat. No.: HY-P703685
Handling Instructions Technical Support

GIPR Protein, Cynomolgus (HEK293, His, Avi) is the recombinant cynomolgus-derived GIPR protein, expressed by HEK293, with C-His & Avi tag.

For research use only. We do not sell to patients.

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Description

GIPR Protein, Cynomolgus (HEK293, His, Avi) is the recombinant cynomolgus-derived GIPR protein, expressed by HEK293, with C-His & Avi tag.
Background

The GIPR protein functions as a receptor for glucose-dependent insulinotropic polypeptide (GIP). Its activity is mediated by G proteins, specifically those that activate adenylyl cyclase. Notably, GIPR has the potential to form homodimers and heterodimers with GLP1R, suggesting a possible interaction between receptors associated with incretin hormones.
Species

Cynomolgus
Source

HEK293
Tag

C-8*His;Avi
Accession

XP_005589662 (G26-Q138)
Protein Length

Partial
Predicted Molecular Mass
15.9 kDa
Molecular Weight

Approximately 28-40 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

GIPR Protein, Cynomolgus (HEK293, His, Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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