2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. OPC-4392

OPC-4392 is a orally active presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. OPC 4392 reverses the Reserpine (HY-N0480)-induced dopamine accumulation, inhibits Apomorphine (HY-12723)-induced stereotypic and climbing behaviors in mouse models. OPC-4392 can be used as antipsychotic agent.

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OPC-4392

OPC-4392 Chemical Structure

CAS No. : 111073-34-8

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Description

OPC-4392 is a orally active presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. OPC 4392 reverses the Reserpine (HY-N0480)-induced dopamine accumulation, inhibits Apomorphine (HY-12723)-induced stereotypic and climbing behaviors in mouse models. OPC-4392 can be used as antipsychotic agent[1][2].

Molecular Weight

391.51

Formula

C24H29N3O2
CAS No.
SMILES

CC(C(C)=CC=C1)=C1N(CC2)CCN2CCCOC3=CC=C(C=CC4=O)C(N4)=C3
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Purity & Documentation
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OPC-4392 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OPC-4392111073-34-8OPC4392OPC 4392Dopamine Receptordopamine autoreceptorD2antipsychoticInhibitorinhibitorinhibit

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