2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. Lotamilast (Standard)

Lotamilast (Standard) is the analytical standard of Lotamilast. This product is intended for research and analytical applications. Lotamilast (RVT-501; E6005) is a selective phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 2.8 nM.

For research use only. We do not sell to patients.

Lotamilast (Standard) Chemical Structure

Lotamilast (Standard) Chemical Structure

CAS No. : 947620-48-6

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Description
Molecular Weight

472.49

Formula

C26H24N4O5
CAS No.
SMILES

O=C(C1=CC=C(C(OC)=O)C=C1)NC2=CC=CC(C3=C4C(C=C(OC)C(OC)=C4)=NC(NC)=N3)=C2
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Lotamilast (Standard) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lotamilast (Standard)947620-48-6Phosphodiesterase (PDE)Inhibitorinhibitorinhibit

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