Kisspeptin-10 (mouse, rat)

Cat. No.: HY-P1197 Purity: 99.53%: Data Sheet
COA

SDS
Handling Instructions
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Kisspeptin-10 (mouse, rat) is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10 (mouse, rat) is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Kisspeptin-10 (mouse, rat) Chemical Structure

CAS No. : 478507-53-8

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Kisspeptin-10 (mouse, rat):

Kisspeptin-10, human In-stock
Kisspeptin-10 (mouse, rat) (TFA) In-stock

1 Publications Citing Use of MCE Kisspeptin-10 (mouse, rat)

•Head Neck. 2024 Dec 26. [Abstract]

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

GPR54^[1]
Angiogenesis^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	2.5 nM Compound: 1, KP10	Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 NW Ca2+ assay Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 NW Ca2+ assay	[PMID: 25811530]

Molecular Weight

1318.44

Formula

C₆₃H₈₃N₁₇O₁₅

CAS No.

478507-53-8

Appearance

Solid

Color

White to off-white

Sequence Shortening

YNWNSFGLRY-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (37.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.7585 mL	3.7924 mL	7.5847 mL
5 mM	0.1517 mL	0.7585 mL	1.5169 mL
10 mM	0.0758 mL	0.3792 mL	0.7585 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.53%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (247 KB) LCMS (101 KB)

Handling Instructions (2659 KB)

References

[1]. Güvenç M, et al. Ameliorating effect of kisspeptin-10 on methotrexate-induced sperm damages and testicular oxidative stress in rats. Andrologia. 2018 Oct;50(8):e13057. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.7585 mL	3.7924 mL	7.5847 mL	18.9618 mL
	5 mM	0.1517 mL	0.7585 mL	1.5169 mL	3.7924 mL
	10 mM	0.0758 mL	0.3792 mL	0.7585 mL	1.8962 mL
	15 mM	0.0506 mL	0.2528 mL	0.5056 mL	1.2641 mL
	20 mM	0.0379 mL	0.1896 mL	0.3792 mL	0.9481 mL
	25 mM	0.0303 mL	0.1517 mL	0.3034 mL	0.7585 mL
	30 mM	0.0253 mL	0.1264 mL	0.2528 mL	0.6321 mL