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  3. Fluorescent Dye
  4. Golgi-P

Golgi-P is a near-infrared Golgi-targeted fluorescent probe specifically used for the detection of Golgi polarity in living cells and living tissues. Golgi-P exhibits a significant polarity-dependent spectral behavior, with its emission wavelength shifting redward with polarity (Ex/Em: 700 nm/780-825 nm). Golgi-P achieves near-infrared fluorescence imaging directly in the brain tissue of depressed mice. Golgi-P combines polarity sensing with Golgi-targeting functionality, providing a new tool for the molecular diagnosis of depression.

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Golgi-P

Golgi-P Chemical Structure

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Description

Golgi-P is a near-infrared Golgi-targeted fluorescent probe specifically used for the detection of Golgi polarity in living cells and living tissues. Golgi-P exhibits a significant polarity-dependent spectral behavior, with its emission wavelength shifting redward with polarity (Ex/Em: 700 nm/780-825 nm). Golgi-P achieves near-infrared fluorescence imaging directly in the brain tissue of depressed mice. Golgi-P combines polarity sensing with Golgi-targeting functionality, providing a new tool for the molecular diagnosis of depression[1].

Molecular Weight

680.01

Formula

C36H37BClF2NO5S
SMILES

CC1(C)C(C=CC=C2)=C2N(CCC(C[C@@](C(O)=O)([H])CS)=O)/C1=C/C=C3CCCC(/C=C/C4=[O+][B-](F)(OC(C5=CC=CC=C5)=C4)F)=C\3Cl
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Room temperature in continental US; may vary elsewhere.
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Golgi-P Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Golgi-PFluorescent DyeGolgi apparatuspolarity sensingnear-infrared fluorescencedepression diagnosisBDNFin vivo imagingfluorescent probeInhibitorinhibitorinhibit

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