2. Gene
  3. Nkd1 - naked cuticle 1 Gene

Nkd1 - naked cuticle 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Nkd; 2810434J10Rik; 9030215G15Rik

Gene ID: 93960 | Gene type: protein coding

About Nkd1

Summary

Enables PDZ domain binding activity. Involved in negative regulation of convergent extension involved in axis elongation and regulation of Wnt signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of protein Phosphatase type 2A complex. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; retina; and unsegmented mesenchyme. Orthologous to human NKD1 (NKD inhibitor of Wnt signaling pathway 1). [provided by Alliance of Genome Resources, Apr 2022]

Nkd1 Products(2)

mRNA Protein Name
NM_001163660.1 NP_001157132.1 protein naked cuticle homolog 1 isoform 2
NM_027280.3 NP_081556.3 protein naked cuticle homolog 1 isoform 1
Protein Preferred Names Protein Names

protein naked cuticle homolog 1

mNkd

mNkd1

naked cuticle 1 homolog

naked-1

Nkd1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Nkd1 Q99MH6 dsh Drosophila melanogaster P51140
Y2H
11356022
Cross
Nkd1 Q99MH6 dsh Drosophila melanogaster P51140
Pull Down
11356022
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09317 NKD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20308 Nkd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26816 Nkd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nkd1 NCBI NCBI:85407