CHURC1 - churchill domain containing 1 Gene

Homo sapiens

Also known as chch; My015; C14orf52

Gene ID: 91612 | Gene type: protein coding

About CHURC1

Cytogenetic location: 14q23.3 Genomic coordinates (GRCh38): 14:64,914,455-64,935,368 (from NCBI)

This gene has 8 transcripts (splice variants) and 175 orthologues. Ubiquitous expression in fat (RPKM 18.1), brain (RPKM 17.2) and 25 other tissues.

Summary

Predicted to enable zinc ion binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated. [provided by Alliance of Genome Resources, Apr 2022]

CHURC1 Products(3)

mRNA	Protein	Name
NM_001204064.2	NP_001190993.2	protein Churchill isoform 3
NM_001386928.1	NP_001373857.1	protein Churchill isoform 2
NM_145165.4	NP_660148.4	protein Churchill isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CHURC1 Protein Structure

Churchill

0
100
139 a.a.

Protein Preferred Names

Protein Names

protein Churchill

CHURC1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CHURC1	Q8WUH1	ZNF581	Homo sapiens	Q9P0T4	Y2H Prey Pooling	32296183
Intra	CHURC1	Q8WUH1	ZNF581	Homo sapiens	Q9P0T4	Validated Y2H	32296183
Intra	CHURC1	Q8WUH1	ZNF581	Homo sapiens	Q9P0T4	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Gastrojejunal Ulcer

Acute Gastrojejunal Ulcer With Hemorrhage	Acute Gastrojejunal Ulcer With Hemorrhage And Obstruction
Acute Gastrojejunal Ulcer With Hemorrhage And Perforation	Acute Gastrojejunal Ulcer With Hemorrhage And Perforation, With Obstruction
Acute Gastrojejunal Ulcer With Hemorrhage, With Perforation And With Obstruction	Acute Gastrojejunal Ulcer With Perforation
Acute Gastrojejunal Ulcer With Perforation And Obstruction	Acute Gastrojejunal Ulcer With Perforation, With Obstruction
Acute Gastrojejunal Ulcer Without Hemorrhage And Without Perforation	Acute Gastrojejunal Ulcer Without Hemorrhage, Without Perforation And Without Obstruction
Acute Gastrojejunal Ulcer Without Mention Of Hemorrhage Or Perforation, Without Mention Of Obstruction	Acute Gastrojejunal Ulcer, With Hemorrhage, With Obstruction
Chronic Gastrojejunal Ulcer Without Hemorrhage And Without Perforation	Chronic Gastrojejunal Ulcer Without Hemorrhage, Without Perforation And Without Obstruction
Chronic Gastrojejunal Ulcer Without Mention Of Hemorrhage Or Perforation, Without Mention Of Obstruction	Marginal Ulcer

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02701	CHURC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CHURC1	VGNC	VGNC:27355
Rattus norvegicus	CHURC1	RGD	RGD:1305116
Canis familiaris	CHURC1	VGNC	VGNC:39262
Mus musculus	CHURC1	MGD	MGI:1923684

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