Gmeb2 - glucocorticoid modulatory element binding protein 2 Gene

Rattus norvegicus

Gene ID: 83635 | Gene type: protein coding

About Gmeb2

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human GMEB2 (glucocorticoid modulatory element binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Gmeb2 Products(2)

mRNA	Protein	Name
NM_001389211.1	NP_001376140.1	glucocorticoid modulatory element-binding protein 2 isoform 2
NM_031803.2	NP_113991.2	glucocorticoid modulatory element-binding protein 2 isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	10894151	RGD
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	14705952	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	10894151	RGD
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	10894151	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	10894151	RGD
involved in regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	14705952	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

glucocorticoid modulatory element-binding protein 2

GMEB-2

Gmeb2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Cross	Gmeb2	O88873	GMEB1	Homo sapiens	Q9Y692-2	Anti Tag CoIP	10894151

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05517	GMEB2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21584	Gmeb2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS28102	Gmeb2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gmeb2	NCBI	NCBI:26205

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