2. Gene
  3. Sort1 - sortilin 1 Gene

Sort1 - sortilin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Nt3; Nts3

Gene ID: 83576 | Gene type: protein coding

About Sort1

Summary

Predicted to enable several functions, including nerve growth factor binding activity; nerve growth factor receptor activity; and Neurotensin Receptor activity, non-G protein-coupled. Involved in positive regulation of epithelial cell apoptotic process. Located in several cellular components, including dendrite; neuronal cell body; and plasma membrane. Is integral component of membrane. Orthologous to human SORT1 (sortilin 1). [provided by Alliance of Genome Resources, Apr 2022]

Sort1 Products(1)

mRNA Protein Name
NM_031767.1 NP_113955.1 sortilin precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of epithelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
22555848 RGD
Cellular Component GO Annotation Evidence Reference Source
located in dendrite IDA
IDA: Inferred from direct assay
12746864 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
12746864 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sortilin

NTR3

glycoprotein 110

gp110

neurotensin receptor 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120821 Endosidin-2 Modulator 99.17% Unkown
HY-153686 BVFP Inhibitor 98.12% Unkown
HY-RS13575 SORT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W747072 3-Sulfo-taurocholic Acid Disodium Salt ≥99.0% Unkown
HY-132975 PrDiAzK Inhibitor / Unkown
HY-153687 SORT-PGRN interaction inhibitor 2 Inhibitor / Unkown
HY-159868 SORT1-IN-1 Inhibitor / Unkown
HY-159875 SORT1-IN-2 Inhibitor / Unkown
HY-159876 SORT1-IN-3 Inhibitor / Unkown
HY-159877 SORT1-IN-4 Inhibitor / Unkown
HY-159878 SORT1-IN-5 Inhibitor / Unkown
HY-D1581 BODIPY 505/515-8-C3-COOH 99.92% Unkown
HY-RS21049 Sort1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27567 Sort1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sort1 NCBI NCBI:6272