Hsf2bp - heat shock transcription factor 2 binding protein Gene

Mus musculus

Also known as Meilb2; 4932437G14Rik

Gene ID: 74377 | Gene type: protein coding

About Hsf2bp

Summary

Involved in meiosis I and spermatogenesis. Located in chromosome. Is expressed in several structures, including genitourinary system; nervous system; sensory organ; surface ectoderm; and thymus. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 19. Orthologous to human HSF2BP (heat shock transcription factor 2 binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Hsf2bp Products(1)

mRNA	Protein	Name
NM_028902.1	NP_083178.1	heat shock factor 2-binding protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	23707421	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in double-strand break repair involved in meiotic recombination	IDA IDA: Inferred from direct assay	30760716	MGI
involved in female meiosis I	IMP IMP: Inferred from mutant phenotype	32845237	MGI
involved in male meiosis I	IDA IDA: Inferred from direct assay	30760716	MGI
involved in spermatogenesis	IDA IDA: Inferred from direct assay	31242413	MGI
involved in spermatogenesis	IMP IMP: Inferred from mutant phenotype	30760716	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in chromosome	IDA IDA: Inferred from direct assay	30760716	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

heat shock factor 2-binding protein

meiotic localizer of BRCA2

Hsf2bp Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Hsf2bp	Q9D4G2	Bnc1	Mus musculus	O35914	IF	23707421

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06410	HSF2BP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21866	Hsf2bp Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hsf2bp	NCBI	NCBI:11077

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