2. Gene
  3. Rnf146 - ring finger protein 146 Gene

Rnf146 - ring finger protein 146 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Iduna; 2610509H23Rik

Gene ID: 68031 | Gene type: protein coding

About Rnf146

Summary

Predicted to enable poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of hydrogen peroxide-induced cell death; positive regulation of canonical Wnt signaling pathway; and protein ubiquitination. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm and nucleus. Is expressed in genitourinary system. Used to study cleidocranial dysplasia. Orthologous to human RNF146 (ring finger protein 146). [provided by Alliance of Genome Resources, Apr 2022]

Rnf146 Products(5)

mRNA Protein Name
NM_001110196.1 NP_001103666.1 E3 ubiquitin-protein ligase RNF146
NM_001110197.1 NP_001103667.1 E3 ubiquitin-protein ligase RNF146
NM_001110198.1 NP_001103668.1 E3 ubiquitin-protein ligase RNF146
NM_001284279.1 NP_001271208.1 E3 ubiquitin-protein ligase RNF146
NM_026518.4 NP_080794.2 E3 ubiquitin-protein ligase RNF146
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF146

RING-type E3 ubiquitin transferase RNF146

Rnf146 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Rnf146 Q9CZW6 UBE2D1 Homo sapiens P51668
X-Ray Diffraction
25327252
Cross
Rnf146 Q9CZW6 UBE2D1 Homo sapiens P51668
NMR
25327252
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-135782 iso-ADP ribose / Unkown
HY-162175 TAMRA-isoADPr / Unkown
HY-RS12056 RNF146 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20592 Rnf146 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27100 Rnf146 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf146 NCBI NCBI:81847