2. Gene
  3. Ddb1 - damage-specific DNA binding protein 1 Gene

Ddb1 - damage-specific DNA binding protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 64470 | Gene type: protein coding

About Ddb1

Summary

Enables damaged DNA binding activity. Predicted to be involved in several processes, including cellular protein metabolic process; positive regulation by virus of viral protein levels in host cell; and positive regulation of gluconeogenesis. Predicted to act upstream of or within Wnt signaling pathway; negative regulation of apoptotic process; and proteasomal protein catabolic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of Cul4A-RING E3 ubiquitin Ligase complex and Cul4B-RING E3 ubiquitin Ligase complex. Predicted to be active in nucleus and site of double-strand break. Orthologous to human DDB1 (damage specific DNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ddb1 Products(1)

mRNA Protein Name
NM_171995.2 NP_741992.2 DNA damage-binding protein 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables damaged DNA binding IMP
IMP: Inferred from mutant phenotype
12145536 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA damage-binding protein 1

damage-specific DNA binding protein 1, 127kDa

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14658 Thalidomide Inducer 99.98% Yes
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-133870 Itaconate-alkyne 98.01% Unkown
HY-144981 HQ461 Inhibitor 98.10% Unkown
HY-W181530 NCT02 98.14% Unkown
HY-163944 LL-K12-18 98.42% Unkown
HY-122653A CCT367766 formic 98.10% Unkown
HY-161166 MM-02-57 / Unkown
HY-161633 PROTAC EGFR degrader 11 Degrader 99.20% Unkown
HY-14658S Thalidomide-d4 Inducer 98.00% Unkown
HY-122653 CCT367766 / Unkown
HY-150641 CDK-IN-9 / Unkown
HY-161167 MM-02-08 Degrader / Unkown
HY-161632 PROTAC EGFR degrader 10 Degrader / Unkown
HY-RS03606 DDB1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17951 Ddb1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24422 Ddb1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddb1 NCBI NCBI:1642