2. Gene
  3. Cd19 - CD19 molecule Gene

Cd19 - CD19 molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 365367 | Gene type: protein coding

About Cd19

Summary

Predicted to be involved in several processes, including B cell activation; B cell receptor signaling pathway; and positive regulation of phosphatidylinositol 3-kinase activity. Predicted to act upstream of or within positive regulation of release of sequestered calcium ion into cytosol. Predicted to be integral component of plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human CD19 (CD19 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd19 Products(1)

mRNA Protein Name
NM_001013237.4 NP_001013255.2 B-lymphocyte antigen CD19 precursor
Protein Preferred Names Protein Names

B-lymphocyte antigen CD19

CD19 antigen

Related Agents

Approval
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9963 Blinatumomab Inhibitor 98.78% Unkown
HY-P99113 Inebilizumab Inhibitor 99.00% Unkown
HY-P99338 Tisagenlecleucel / Unkown
Clinical Phase
Inhibitory Antibodies (6)
Cat. No. Product Name Effect
Purity Phase
HY-P99711 Loncastuximab Inhibitor ≥99.0% Phase 3
HY-P99761 Obexelimab Inhibitor ≥99.0% Phase 3
HY-P99285 Denintuzumab Inhibitor ≥99.0% Phase 2
HY-P990729 Budoprutug / Phase 2
HY-P99868 Duvortuxizumab ≥99.0% Phase 1
HY-P990694 Zeripatamig ≥99.0% Phase 1
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153084 CD19 CAR mRNA (Mouse) / Unkown
HY-153084A CD19 CAR mRNA (Human) / Unkown
HY-153233 CD19 car mRNA (Mouse)-LNP ≥90.0% Unkown
HY-153234 CD19 car circRNA-LNP / Unkown
HY-153085 CD19 CAR circRNA / Unkown
Inhibitory Antibodies (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99113A Inebilizumab (FUT8-KO) 97% Unkown
HY-P99976 Anti-Mouse CD19 Antibody (1D3) Inhibitor 95.00% Unkown
HY-P990017 Englumafusp alfa Inhibitor 99.93% Unkown
HY-P990349 Anti-CD19 Antibody Inhibitor / Unkown
HY-P99914 Emfizatamab / Unkown
HY-P99577 Taplitumomab / Unkown
HY-P991231 DI-B4 Inhibitor / Unkown
HY-P990571 Coltuximab Inhibitor / Unkown
HY-P990870 Anti-CD19 Antibody (4G7) / Unkown
HY-P991176 RG-6333 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd19 NCBI NCBI:930
Macaca fascicularis Cd19 NCBI NCBI:102145514
Mus musculus Cd19 NCBI NCBI:12478
Macaca mulatta Cd19 NCBI NCBI:705211