2. Gene
  3. Mettl3 - methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Gene

Mettl3 - methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 361035 | Gene type: protein coding

About Mettl3

Summary

Predicted to enable several functions, including S-adenosyl-L-methionine binding activity; mRNA (N6-adenosine)-methyltransferase activity; and protein heterodimerization activity. Predicted to be involved in several processes, including RNA metabolic process; gamete generation; and regulation of translation. Predicted to be located in nuclear speck. Predicted to be part of RNA N6-methyladenosine methyltransferase complex. Predicted to be active in nucleus. Orthologous to human METTL3 (methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]

Mettl3 Products(1)

mRNA Protein Name
NM_001024794.1 NP_001019965.1 N6-adenosine-methyltransferase catalytic subunit
Protein Preferred Names Protein Names

N6-adenosine-methyltransferase catalytic subunit

N6-adenosine-methyltransferase 70 kDa subunit

methyltransferase-like 3

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-156677 STC-15 Inhibitor 99.90% Phase 1
Pre-clinical Phase
Bioactive Molecules (24)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-134836 STM2457 Inhibitor 99.86% Unkown
HY-162080 METTL1-WDR4-IN-1 Inhibitor 98.87% Unkown
HY-115717 UZH2 Inhibitor 98.91% Unkown
HY-156773 STM3006 Inhibitor 98.71% Unkown
HY-160415A WD6305 TFA Inhibitor 99.81% Unkown
HY-W037893 METTL3 activator-1 Activator 99.38% Unkown
HY-153625 STM2120 Inhibitor 99.92% Unkown
HY-158404 METTL3-IN-8 Inhibitor 99.81% Unkown
HY-P10387A RSM3 TFA Inhibitor 98.83% Unkown
HY-P10387 RSM3 Inhibitor 95.73% Unkown
HY-159604 METTL3-IN-9 Inhibitor 95.30% Unkown
HY-134673B UZH1b Inhibitor 99.75% Unkown
HY-158403 METTL3-IN-7 Inhibitor / Unkown
HY-148467 METTL3-IN-1 Inhibitor / Unkown
HY-148468 METTL3-IN-2 Inhibitor / Unkown
HY-174873 AF151 Degrader / Unkown
HY-174874 POI-4 / Unkown
HY-160415 WD6305 Inhibitor / Unkown
HY-W125425 Methyl piperazine-2-carboxylate Activator / Unkown
HY-154997 7OQL Inhibitor / Unkown
HY-162930 PROTAC METTL3 degrader 1 Degrader / Unkown
HY-148469 METTL3-IN-3 Inhibitor / Unkown
HY-156759 METTL3-IN-5 Inhibitor / Unkown
HY-168878 EP652 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mettl3 NCBI NCBI:56339