2. Gene
  3. Foxp3 - forkhead box P3 Gene

Foxp3 - forkhead box P3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1562112

Gene ID: 317382 | Gene type: protein coding

About Foxp3

Summary

Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; NFAT protein binding activity; and enzyme binding activity. Involved in several processes, including establishment of endothelial blood-brain barrier; negative regulation of defense response to virus; and response to rapamycin. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nucleus. Used to study intrahepatic cholangiocarcinoma. Biomarker of Korean hemorrhagic fever; asthma; bronchiolitis obliterans; hypertension; and hypothyroidism. Human ortholog(s) of this gene implicated in Human papillomavirus infectious disease; colorectal cancer; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Orthologous to human FOXP3 (forkhead box P3). [provided by Alliance of Genome Resources, Apr 2022]

Foxp3 Products(1)

mRNA Protein Name
NM_001108250.1 NP_001101720.1 forkhead box protein P3
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in establishment of endothelial blood-brain barrier IEP
IEP: Inferred from expression pattern
31027862 RGD
involved in negative regulation of defense response to virus IMP
IMP: Inferred from mutant phenotype
17878294 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
19998507 RGD
involved in response to rapamycin IEP
IEP: Inferred from expression pattern
24507682 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

forkhead box protein P3

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13624A Epirubicin hydrochloride 99.16% Yes
HY-13624 Epirubicin 98.45% Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-148808 Zelasudil Inhibitor 99.33% Phase 2
Pre-clinical Phase
Bioactive Molecules (19)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-126675A AS2863619 99.94% Unkown
HY-124131 DS-437 Inhibitor 98.00% Unkown
HY-W107024 BMS-986260 Inhibitor 99.95% Unkown
HY-126675 AS2863619 free base 99.87% Unkown
HY-P1453A CMD178 TFA Inhibitor 99.71% Unkown
HY-RS05075 FOXP3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-P1684 Peptide P60 Inhibitor / Unkown
HY-P1453 CMD178 Inhibitor / Unkown
HY-160040A Cobitolimod sodium Agonist / Unkown
HY-15091 Anisperimus / Unkown
HY-159692 AZD8701 Inhibitor / Unkown
HY-159692A AZD8701 sodium Inhibitor / Unkown
HY-160040 Cobitolimod Agonist / Unkown
HY-162600 CDK8-IN-15 Inhibitor / Unkown
HY-162943 P60-L3-VHL / Unkown
HY-P10808 RSRGVFF Inhibitor / Unkown
HY-162946 Alkyne-P60 / Unkown
HY-RS16899 Foxp3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23341 Foxp3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991180 TRX-518 Ligand / Unkown
HY-P991392 TGTB227 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxp3 NCBI NCBI:50943