2. Gene
  3. Frs2 - fibroblast growth factor receptor substrate 2 Gene

Frs2 - fibroblast growth factor receptor substrate 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 314850 | Gene type: protein coding

About Frs2

Summary

Predicted to enable Fibroblast Growth Factor receptor binding activity; neurotrophin TrkA receptor binding activity; and transmembrane receptor protein tyrosine kinase adaptor activity. Involved in cellular response to Fibroblast Growth Factor stimulus and positive regulation of vascular associated smooth muscle cell proliferation. Predicted to be located in adherens junction and plasma membrane. Predicted to be active in cell-cell junction and cytoplasm. Orthologous to human FRS2 (Fibroblast Growth Factor receptor substrate 2). [provided by Alliance of Genome Resources, Apr 2022]

Frs2 Products(1)

mRNA Protein Name
NM_001108097.4 NP_001101567.2 fibroblast growth factor receptor substrate 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to fibroblast growth factor stimulus IMP
IMP: Inferred from mutant phenotype
28947594 RGD
involved in positive regulation of vascular associated smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
28947594 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor receptor substrate 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-158248 FGFR4-IN-19 Inhibitor / Unkown
HY-172916 LC-SF-14 Inhibitor / Unkown
HY-RS05112 FRS2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22174 Frs2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28696 Frs2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Frs2 NCBI NCBI:10818