2. Gene
  3. C1qbp - complement C1q binding protein Gene

C1qbp - complement C1q binding protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Habp1; gC1qR

Gene ID: 29681 | Gene type: protein coding

About C1qbp

Summary

Enables Adrenergic Receptor binding activity; complement component C1q complex binding activity; and protein kinase C binding activity. Predicted to be involved in several processes, including positive regulation of cell migration; regulation of gene expression; and regulation of intracellular signal transduction. Located in cytoplasm; extracellular space; and nucleus. Is active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 33. Orthologous to human C1QBP (complement C1q binding protein). [provided by Alliance of Genome Resources, Apr 2022]

C1qbp Products(1)

mRNA Protein Name
NM_019259.2 NP_062132.2 complement component 1 Q subcomponent-binding protein, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables adrenergic receptor binding IDA
IDA: Inferred from direct assay
10409668 RGD
enables complement component C1q complex binding IDA
IDA: Inferred from direct assay
9414106 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10409668 RGD
enables protein kinase C binding IDA
IDA: Inferred from direct assay
11698413 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in GABA-ergic synapse EXP
EXP: Inferred from Experiment
23622064 RGD
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
23622064 RGD
located in cytoplasm IDA
IDA: Inferred from direct assay
10409668 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
9414106 RGD
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
23622064 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23622064 RGD
is active in presynaptic active zone EXP
EXP: Inferred from Experiment
23622064 RGD
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
23622064 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement component 1 Q subcomponent-binding protein, mitochondrial

GC1q-R protein

complement component 1, q subcomponent binding protein

glycoprotein gC1qBP

C1qbp Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
C1qbp O35796 ADRA1B Mesocricetus auratus P18841
Y2H
10409668
Cross
C1qbp O35796 ADRA1B Mesocricetus auratus P18841
Confocal
10409668
Cross
C1qbp O35796 ADRA1B Mesocricetus auratus P18841
Anti Bait CoIP
10409668
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01720 C1QBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17652 C1qbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24112 C1qbp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990844 Anti-GC1q R/C1QBP Antibody (60.11) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C1qbp NCBI NCBI:708
Mus musculus C1qbp NCBI NCBI:12261