2. Gene
  3. Sp4 - Sp4 transcription factor Gene

Sp4 - Sp4 transcription factor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as HF-1b

Gene ID: 25162 | Gene type: protein coding

About Sp4

Summary

Enables DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of heart contraction. Located in nucleus. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Orthologous to human SP4 (Sp4 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Sp4 Products(1)

mRNA Protein Name
NM_012761.2 NP_036893.1 transcription factor Sp4
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
15572681 RGD
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
12746457 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Sp4

HF-1b zinc finger protein

trans-acting transcription factor 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-156276 SP4e Activator 99.72% Unkown
HY-156277 SP4f Activator 99.77% Unkown
HY-RS13607 SP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18331 Sp4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24810 Sp4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sp4 NCBI NCBI:6671
Mus musculus Sp4 NCBI NCBI:20688