2. Gene
  3. Sp4 - trans-acting transcription factor 4 Gene

Sp4 - trans-acting transcription factor 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HF-1b; HF1-b; 5730497N03Rik

Gene ID: 20688 | Gene type: protein coding

About Sp4

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Acts upstream of or within regulation of heart contraction. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Orthologous to human SP4 (Sp4 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Sp4 Products(2)

mRNA Protein Name
NM_001166385.2 NP_001159857.2 transcription factor Sp4 isoform 2
NM_009239.4 NP_033265.4 transcription factor Sp4 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within regulation of heart contraction IMP
IMP: Inferred from mutant phenotype
11007485 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Sp4

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-156276 SP4e Activator 99.72% Unkown
HY-156277 SP4f Activator 99.77% Unkown
HY-RS13607 SP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18331 Sp4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24810 Sp4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sp4 NCBI NCBI:6671