Fabp1 - fatty acid binding protein 1 Gene

Rattus norvegicus

Also known as SCP; p14; SCP.; Fabplg; L-FABP

Gene ID: 24360 | Gene type: protein coding

About Fabp1

Summary

Enables several functions, including long-chain fatty acid transporter activity; monocarboxylic acid binding activity; and phospholipid binding activity. Involved in several processes, including intestinal absorption; long-chain fatty acid transport; and positive regulation of fatty acid beta-oxidation. Located in several cellular components, including apical cortex; cytosol; and peroxisomal matrix. Part of protein-containing complex. Orthologous to human FABP1 (fatty acid binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Fabp1 Products(1)

mRNA	Protein	Name
NM_012556.2	NP_036688.1	fatty acid-binding protein, liver

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables bile acid binding	IMP IMP: Inferred from mutant phenotype	12479568	RGD
enables fatty acid binding	IDA IDA: Inferred from direct assay	3478711	RGD
enables fatty acid binding	IPI IPI: Inferred from physical interaction	10666570	RGD
enables heterocyclic compound binding	IDA IDA: Inferred from direct assay	1939124	RGD
enables heterocyclic compound binding	IPI IPI: Inferred from physical interaction	1939124	RGD
enables long-chain fatty acid transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	15035630	RGD
enables oleic acid binding	IPI IPI: Inferred from physical interaction	1939124	RGD
enables phospholipid binding	IMP IMP: Inferred from mutant phenotype	12479568	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	24140341	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in intestinal absorption	IDA IDA: Inferred from direct assay	10666570	RGD
involved in long-chain fatty acid transport	IMP IMP: Inferred from mutant phenotype	15035630	RGD
involved in positive regulation of fatty acid beta-oxidation	IDA IDA: Inferred from direct assay	16262600	RGD
involved in positive regulation of hydrolase activity	IDA IDA: Inferred from direct assay	16262600	RGD
involved in response to vitamin B3	IEP IEP: Inferred from expression pattern	19878707	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in apical cortex	IDA IDA: Inferred from direct assay	10666570	RGD
located in peroxisomal matrix	IDA IDA: Inferred from direct assay	16262600	RGD
part of protein-containing complex	IDA IDA: Inferred from direct assay	22303004	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

fatty acid-binding protein, liver

Z-protein	fatty acid binding protein 1, liver
liver-type fatty acid-binding protein	squalene- and sterol-carrier protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-158127	FABP1-IN-1	Inhibitor	99.95%	Unkown
HY-149831	ZLY28	Modulator	99.95%	Unkown
HY-172883	ABP/PPAR modulator 1	Modulator	/	Unkown
HY-127049	Arachidonic acid-biotin		/	Unkown
HY-161892	FABP4-IN-4	Inhibitor	/	Unkown
HY-RS04656	FABP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS17252	Fabp1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS23706	Fabp1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Fabp1	NCBI	NCBI:2168
Mus musculus	Fabp1	NCBI	NCBI:14080

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