2. Gene
  3. Def6 - differentially expressed in FDCP 6 Gene

Def6 - differentially expressed in FDCP 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ibp; Slat; Slat2; Slat6; 2410003F05Rik; 6430538D02Rik

Gene ID: 23853 | Gene type: protein coding

About Def6

Summary

Located in cell-cell junction. Is expressed in several structures, including heart; hemolymphoid system; lung; metanephros; and musculature. Used to study systemic lupus erythematosus. Orthologous to human DEF6 (DEF6 guanine nucleotide exchange factor). [provided by Alliance of Genome Resources, Apr 2022]

Def6 Products(1)

mRNA Protein Name
NM_027185.3 NP_081461.2 differentially expressed in FDCP 6
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17403664 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
23793062 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

differentially expressed in FDCP 6

DEF-6

IRF-4-binding protein

IRF4-binding protein

SWAP-70-like adapter of T-cells

Def6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Def6 Q8C2K1 Itga7 Mus musculus Q61738-6
IF
17403664
Intra
Def6 Q8C2K1 Itga7 Mus musculus Q61738-6
Y2H
17403664
Intra
Def6 Q8C2K1 Itga7 Mus musculus Q61738-6
Anti Tag CoIP
17403664
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03671 DEF6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03677 DEFA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21321 Def6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27840 Def6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Def6 NCBI NCBI:50619