Ythdf1 - YTH N6-methyladenosine RNA binding protein 1 Gene

Mus musculus

Also known as 8030473O16; 2210410K23Rik

Gene ID: 228994 | Gene type: protein coding

About Ythdf1

Summary

Enables N6-methyladenosine-containing RNA binding activity. Involved in several processes, including learning or memory; regulation of long-term synaptic potentiation; and regulation of translation. Located in cytoplasm. Is expressed in future spinal cord and spinal cord. Orthologous to human YTHDF1 (YTH N6-methyladenosine RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ythdf1 Products(1)

mRNA	Protein	Name
NM_173761.3	NP_776122.1	YTH domain-containing family protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables N6-methyladenosine-containing RNA reader activity	IDA IDA: Inferred from direct assay	30401835	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in learning	IMP IMP: Inferred from mutant phenotype	30401835	MGI
involved in mRNA destabilization	IMP IMP: Inferred from mutant phenotype	32943573	MGI
involved in memory	IMP IMP: Inferred from mutant phenotype	30401835	MGI
involved in positive regulation of translation	IDA IDA: Inferred from direct assay	30401835	MGI
NOT involved in positive regulation of translational initiation	IMP IMP: Inferred from mutant phenotype	32943573	MGI
involved in regulation of antigen processing and presentation	IMP IMP: Inferred from mutant phenotype	30728504	MGI
involved in regulation of axon guidance	IMP IMP: Inferred from mutant phenotype	30843071	MGI
involved in regulation of long-term synaptic potentiation	IMP IMP: Inferred from mutant phenotype	30401835	MGI
involved in regulation of mRNA stability	IMP IMP: Inferred from mutant phenotype	32943573	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	32943573	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

YTH domain-containing family protein 1

DACA-1 homolog	YTH domain family 1
YTH domain family protein 1	dermatomyositis associated with cancer putative autoantigen 1 homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-168610	YTH-IN-1	Inhibitor	98.66%	Unkown
HY-176848	SKLB-Y13	Inhibitor	/	Unkown
HY-RS15937	YTHDF1 Human Pre-designed siRNA Set A	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ythdf1	NCBI	NCBI:54915

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