2. Gene
  3. Aars2 - alanyl-tRNA synthetase 2, mitochondrial Gene

Aars2 - alanyl-tRNA synthetase 2, mitochondrial Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm89; Aarsl; AlaRS

Gene ID: 224805 | Gene type: protein coding

About Aars2

Summary

Predicted to enable several functions, including ATP binding activity; catalytic activity, acting on a tRNA; and tRNA binding activity. Predicted to be involved in mitochondrial alanyl-tRNA aminoacylation and tRNA modification. Predicted to act upstream of or within translation. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 8. Orthologous to human AARS2 (alanyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Aars2 Products(2)

mRNA Protein Name
NM_001358000.1 NP_001344929.1 alanine--tRNA ligase, mitochondrial isoform 2
NM_198608.2 NP_941010.2 alanine--tRNA ligase, mitochondrial isoform 1 precursor
Protein Preferred Names Protein Names

alanine--tRNA ligase, mitochondrial

alanyl-tRNA synthetase, mitochondrial

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00029 AARS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00026 AAR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21465 Aars2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27983 Aars2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aars2 NCBI NCBI:57505