2. Gene
  3. Wiz - widely-interspaced zinc finger motifs Gene

Wiz - widely-interspaced zinc finger motifs Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 22404 | Gene type: protein coding

About Wiz

Summary

Enables SET domain binding activity and Histone Methyltransferase binding activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication; protein stabilization; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina. Orthologous to human WIZ (WIZ zinc finger). [provided by Alliance of Genome Resources, Apr 2022]

Wiz Products(32)

mRNA Protein Name
NM_001372219.1 NP_001359148.1 protein Wiz isoform 4
NM_001372220.1 NP_001359149.1 protein Wiz isoform 5
NM_001372221.1 NP_001359150.1 protein Wiz isoform 5
NM_001372222.1 NP_001359151.1 protein Wiz isoform 6
NM_001372223.1 NP_001359152.1 protein Wiz isoform 7
NM_001372224.1 NP_001359153.1 protein Wiz isoform 1
NM_001372225.1 NP_001359154.1 protein Wiz isoform 8
NM_001372226.1 NP_001359155.1 protein Wiz isoform 9
NM_001372227.1 NP_001359156.1 protein Wiz isoform 3
NM_001410390.1 NP_001397319.1 protein Wiz isoform 15
NM_001410391.1 NP_001397320.1 protein Wiz isoform 12
NM_001410392.1 NP_001397321.1 protein Wiz isoform 12
NM_001410393.1 NP_001397322.1 protein Wiz isoform 7
NM_001410394.1 NP_001397323.1 protein Wiz isoform 10
NM_001410395.1 NP_001397324.1 protein Wiz isoform 7
NM_001410396.1 NP_001397325.1 protein Wiz isoform 7
NM_001410397.1 NP_001397326.1 protein Wiz isoform 16
NM_001410398.1 NP_001397327.1 protein Wiz isoform 1
NM_001410399.1 NP_001397328.1 protein Wiz isoform 8
NM_001410400.1 NP_001397329.1 protein Wiz isoform 13
NM_001410401.1 NP_001397330.1 protein Wiz isoform 13
NM_001410402.1 NP_001397331.1 protein Wiz isoform 19
NM_001410403.1 NP_001397332.1 protein Wiz isoform 14
NM_001410404.1 NP_001397333.1 protein Wiz isoform 11
NM_001410405.1 NP_001397334.1 protein Wiz isoform 20
NM_001410406.1 NP_001397335.1 protein Wiz isoform 17
NM_001410407.1 NP_001397336.1 protein Wiz isoform 11
NM_001410408.1 NP_001397337.1 protein Wiz isoform 14
NM_001410409.1 NP_001397338.1 protein Wiz isoform 21
NM_001410410.1 NP_001397339.1 protein Wiz isoform 18
NM_011717.5 NP_035847.2 protein Wiz isoform 2
NM_212438.4 NP_997603.3 protein Wiz isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables SET domain binding IPI
IPI: Inferred from physical interaction
16702210 MGI
enables histone methyltransferase binding IPI
IPI: Inferred from physical interaction
16702210 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16702210 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
16702210 MGI
Cellular Component GO Annotation Evidence Reference Source
NOT located in nucleolus IDA
IDA: Inferred from direct assay
16702210 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16702210 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Wiz

widely-interspaced zinc finger-containing protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (13)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-159099 HbF inducer 2 Degrader 99.15% Unkown
HY-159098 dWIZ-1 Degrader / Unkown
HY-163820 WIZ degrader 4 Degrader 99.37% Unkown
HY-162665 WIZ degrader 1 Inducer / Unkown
HY-163818 WIZ degrader 2 Degrader / Unkown
HY-163819 WIZ degrader 3 Degrader / Unkown
HY-169761 (rac)-dWIZ-1 Degrader / Unkown
HY-169955 WIZ degrader 8 Degrader / Unkown
HY-RS15821 WIZ Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-163822 WIZ degrader 5 Degrader / Unkown
HY-163823 WIZ degrader 6 Degrader / Unkown
HY-163824 WIZ degrader 7 Degrader / Unkown
HY-RS22086 Wiz Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wiz NCBI NCBI:58525