1. Gene
  2. Akr1d1 - aldo-keto reductase family 1, member D1 Gene

Akr1d1 - aldo-keto reductase family 1, member D1 Gene

Mus musculus
Gene ID: 208665 | Gene type: protein coding

About Akr1d1

Summary

Predicted to enable 3-oxo-5-beta-steroid 4-dehydrogenase activity; alditol:NADP+ 1-oxidoreductase activity; and ketosteroid monooxygenase activity. Predicted to be involved in cellular hormone metabolic process; Cholesterol catabolic process; and digestion. Predicted to act upstream of or within bile acid biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; heart; hemolymphoid system gland; and nervous system. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 2. Orthologous to human AKR1D1 (aldo-keto reductase family 1 member D1). [provided by Alliance of Genome Resources, Apr 2022]

Akr1d1 Products(1)

mRNA Protein Name
NM_145364.2 NP_663339.1 aldo-keto reductase family 1 member D1
Protein Preferred Names Protein Names

aldo-keto reductase family 1 member D1

3-oxo-5-beta-steroid 4-dehydrogenase

delta(4)-3-ketosteroid 5-beta-reductase

delta(4)-3-oxosteroid 5-beta-reductase

Orthologs Information

Species Symbol Source ID
Homo sapiens Akr1d1 NCBI NCBI:6718